| Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning N Rocha, C Kuijl, R Van Der Kant, L Janssen, D Houben, H Janssen, ... Journal of Cell Biology 185 (7), 1209-1225, 2009 | 738 | 2009 |
| Amyloid-β-independent regulators of tau pathology in Alzheimer disease R van der Kant, LSB Goldstein, R Ossenkoppele Nature Reviews Neuroscience 21 (1), 21-35, 2020 | 422 | 2020 |
| Cellular functions of the amyloid precursor protein from development to dementia R Van Der Kant, LSB Goldstein Developmental cell 32 (4), 502-515, 2015 | 298 | 2015 |
| The probabilistic model of Alzheimer disease: the amyloid hypothesis revised GB Frisoni, D Altomare, DR Thal, F Ribaldi, R van der Kant, ... Nature Reviews Neuroscience 23 (1), 53-66, 2022 | 275 | 2022 |
| LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF‐κB activation FJ Verweij, MAJ Van Eijndhoven, ES Hopmans, T Vendrig, T Wurdinger, ... The EMBO journal 30 (11), 2115-2129, 2011 | 259 | 2011 |
| Cholesterol metabolism is a druggable axis that independently regulates tau and amyloid-β in iPSC-derived Alzheimer’s disease neurons R van der Kant, VF Langness, CM Herrera, DA Williams, LK Fong, ... Cell stem cell 24 (3), 363-375. e9, 2019 | 253 | 2019 |
| GPR43 potentiates β-cell function in obesity JC McNelis, YS Lee, R Mayoral, R van der Kant, AMF Johnson, J Wollam, ... Diabetes 64 (9), 3203-3217, 2015 | 209 | 2015 |
| Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L R van der Kant, A Fish, L Janssen, H Janssen, S Krom, N Ho, ... Journal of cell science 126 (15), 3462-3474, 2013 | 202 | 2013 |
| Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials R Ossenkoppele, R van der Kant, O Hansson The Lancet Neurology 21 (8), 726-734, 2022 | 162 | 2022 |
| Cholesterol and Alzheimer’s disease; from risk genes to pathological effects FM Feringa, R Van der Kant Frontiers in Aging Neuroscience 13, 690372, 2021 | 141 | 2021 |
| Defective transcytosis of APP and lipoproteins in human iPSC-derived neurons with familial Alzheimer’s disease mutations G Woodruff, SM Reyna, M Dunlap, R Van Der Kant, JA Callender, ... Cell reports 17 (3), 759-773, 2016 | 111 | 2016 |
| Stuck in traffic: an emerging theme in diseases of the nervous system J Neefjes, R van der Kant Trends in neurosciences 37 (2), 66-76, 2014 | 111 | 2014 |
| Characterization of the mammalian CORVET and HOPS complexes and their modular restructuring for endosome specificity R Van Der Kant, CTH Jonker, RH Wijdeven, J Bakker, L Janssen, ... Journal of Biological Chemistry 290 (51), 30280-30290, 2015 | 109 | 2015 |
| Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1 R van der Kant, I Zondervan, L Janssen, J Neefjes Journal of Lipid Research 54 (8), 2153-2165, 2013 | 109 | 2013 |
| Small regulators, major consequences – Ca2+ and cholesterol at the endosome–ER interface R van der Kant, J Neefjes Journal of Cell Science 127 (5), 929-938, 2014 | 106 | 2014 |
| Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments K Uusi-Rauva, A Kyttälä, R van der Kant, J Vesa, K Tanhuanpää, ... Cellular and Molecular Life Sciences 69, 2075-2089, 2012 | 85 | 2012 |
| A reference human induced pluripotent stem cell line for large-scale collaborative studies CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendraat, L Peng, ... Cell Stem Cell 29 (12), 1685-1702. e22, 2022 | 74 | 2022 |
| SKIP‐HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport MLM Jongsma, J Bakker, B Cabukusta, N Liv, D van Elsland, J Fermie, ... The EMBO journal 39 (6), e102301, 2020 | 61 | 2020 |
| Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization VF Langness, R Van der Kant, U Das, L Wang, RS Chaves, ... Molecular Biology of the Cell 32 (3), 247-259, 2021 | 37 | 2021 |
| APOE and immunity: Research highlights CM Kloske, CJ Barnum, AF Batista, EM Bradshaw, AM Brickman, G Bu, ... Alzheimer's & Dementia 19 (6), 2677-2696, 2023 | 7 | 2023 |
