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Jonathan Winger
Jonathan Winger
CEO
Verified email at omniox.com
Title
Cited by
Cited by
Year
Nitric oxide signaling: no longer simply on or off
SPL Cary, JA Winger, ER Derbyshire, MA Marletta
Trends in biochemical sciences 31 (4), 231-239, 2006
2862006
Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP
SPL Cary, JA Winger, MA Marletta
Proceedings of the National Academy of Sciences 102 (37), 13064-13069, 2005
1892005
Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domain
JA Winger, MA Marletta
Biochemistry 44 (10), 4083-4090, 2005
1192005
The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)
JA Winger, O Hantschel, G Superti-Furga, J Kuriyan
BMC structural biology 9, 1-12, 2009
1122009
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
JA Winger, ER Derbyshire, MH Lamers, MA Marletta, J Kuriyan
BMC Structural Biology 8, 1-11, 2008
1112008
Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs
JA Winger, ER Derbyshire, MA Marletta
Journal of Biological Chemistry 282 (2), 897-907, 2007
812007
Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding
PR Visperas, JA Winger, TM Horton, NH Shah, DJ Aum, A Tao, T Barros, ...
Biochemical Journal 465 (1), 149-161, 2015
232015
Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic
J Boehme, N Le Moan, RJ Kameny, A Loucks, MJ Johengen, AL Lesneski, ...
PLoS biology 16 (10), e2005924, 2018
192018
Identification of inhibitors of the association of ZAP-70 with the T cell receptor by high-throughput screen
PR Visperas, CG Wilson, JA Winger, Q Yan, K Lin, MR Arkin, A Weiss, ...
SLAS DISCOVERY: Advancing Life Sciences R&D 22 (3), 324-331, 2017
132017
Compositions and methods for the delivery of oxygen
SPL Cary, EM Boon, E Weinert, JA Winger, MA Marletta
US Patent 8,404,631, 2013
82013
A new paradigm in protecting ischemic brain: preserving the neurovascular unit before reperfusion
N Le Moan, PY Leung, N Rost, JA Winger, A Krtolica, SP Cary
Neuroprotective Therapy for Stroke and Ischemic Disease, 641-664, 2017
72017
Compositions and methods for the delivery of nitric oxide
SPL Cary, EM Boon, JA Winger, MA Marletta
US Patent 8,404,632, 2013
72013
Activation and deactivation of soluble guanylate cyclase: Domain organization and the requirement for non-heme equivalents of nitric oxide
JA Winger
University of Michigan, 2004
62004
Novel oxygen carrier slows infarct growth in large vessel occlusion dog model based on magnetic resonance imaging analysis
MS Shazeeb, RM King, V Anagnostakou, Z Vardar, A Kraitem, J Kolstad, ...
Stroke 53 (4), 1363-1372, 2022
52022
Omx a hypoxia modulator reverses the immunosuppressive glioblastoma microenvironment by stimulating T cell infiltration and activation that results in increased number of long …
NL Moan, P Leung, S Ng, T Davis, C Liang, JW Winger, SP Cary, ...
Cancer Research 77 (13_Supplement), 4686-4686, 2017
42017
Compositions and methods for the delivery of nitric oxide
SPL Cary, EM Boon, JA Winger, MA Marletta
US Patent 9,493,527, 2016
42016
Compositions and methods for the delivery of oxygen
SPL Cary, EM Boon, E Weinert, JA Winger, MA Marletta
US Patent 9,493,526, 2016
42016
Compositions and methods for the delivery of nitric oxide
SPL Cary, EM Boon, JA Winger, MA Marletta
US Patent App. 13/772,283, 2013
32013
Compositions and methods for the delivery of oxygen
SPL Cary, EM Boon, E Weinert, JA Winger, MA Marletta
US Patent App. 13/772,281, 2013
32013
Novel and safe oxygen carrier prevents brain damage after focal ischemia and improves functional outcomes
P Leung, C Bedard, T Davis, S Ng, C Liang, J Lamb, PD Boitano, ...
Stroke 47 (suppl_1), A67-A67, 2016
22016
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