Claudia L. Kleinman
Claudia L. Kleinman
Dirección de correo verificada de mcgill.ca
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Comment on “Widespread RNA and DNA Sequence Differences in the Human Transcriptome”
CL Kleinman, J Majewski
Science 335, 1302-c, 2012
215*2012
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR
CL Kleinman, N Gerges, S Papillon-Cavanagh, P Sin-Chan, ...
Nature genetics 46 (1), 39-44, 2014
1582014
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ...
Nature 572 (7767), 67-73, 2019
1512019
Polyadenylation-dependent control of long noncoding RNA expression by the poly (A)-binding protein nuclear 1
YB Beaulieu, CL Kleinman, AM Landry-Voyer, J Majewski, F Bachand
PLoS Genet 8 (11), e1003078, 2012
1322012
RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression
E Lalonde, KCH Ha, Z Wang, A Bemmo, CL Kleinman, T Kwan, ...
Genome research 21 (4), 545-554, 2011
1312011
H3. 3K27M cooperates with Trp53 loss and PDGFRA gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas
M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ...
Cancer cell 32 (5), 684-700. e9, 2017
1162017
Macrocyclic lactone resistance in Dirofilaria immitis: failure of heartworm preventives and investigation of genetic markers for resistance
C Bourguinat, ACY Lee, R Lizundia, BL Blagburn, JL Liotta, MS Kraus, ...
Veterinary parasitology 210 (3-4), 167-178, 2015
862015
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ...
Nature communications 10 (1), 1-13, 2019
852019
A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability
H Antonicka, K Choquet, ZY Lin, AC Gingras, CL Kleinman, ...
EMBO reports 18 (1), 28-38, 2017
742017
Computational methods for evaluating phylogenetic models of coding sequence evolution with dependence between codons
N Rodrigue, CL Kleinman, H Philippe, N Lartillot
Molecular Biology and Evolution 26 (7), 1663-1676, 2009
542009
Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas
B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ...
Cancer cell 35 (5), 782-797. e8, 2019
512019
Statistical potentials for improved structurally constrained evolutionary models
CL Kleinman, N Rodrigue, N Lartillot, H Philippe
Molecular biology and evolution 27 (7), 1546-1560, 2010
512010
Stalled developmental programs at the root of pediatric brain tumors
S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ...
Nature genetics 51 (12), 1702-1713, 2019
492019
A targetable EGFR-dependent tumor-initiating program in breast cancer
P Savage, A Blanchet-Cohen, T Revil, D Badescu, SMI Saleh, YC Wang, ...
Cell reports 21 (5), 1140-1149, 2017
442017
RNA editing of protein sequences: a rare event in human transcriptomes
CL Kleinman, V Adoue, J Majewski
Rna 18 (9), 1586-1596, 2012
422012
A maximum likelihood framework for protein design
CL Kleinman, N Rodrigue, C Bonnard, H Philippe, N Lartillot
BMC bioinformatics 7 (1), 1-17, 2006
402006
A C19MC-LIN28A-MYCN oncogenic circuit driven by hijacked super-enhancers is a distinct therapeutic vulnerability in ETMRs: a lethal brain tumor
P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, ...
Cancer Cell 36 (1), 51-67. e7, 2019
342019
The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, ...
Nature communications 8 (1), 1-14, 2017
342017
Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas
R Salloum, MK McConechy, LG Mikael, C Fuller, R Drissi, M DeWire, ...
Acta neuropathologica communications 5 (1), 1-12, 2017
332017
SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors
T Shorstova, M Marques, J Su, J Johnston, CL Kleinman, N Hamel, ...
Cancer research 79 (10), 2761-2774, 2019
302019
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Artículos 1–20