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James Brett Case
James Brett Case
Washington University School of Medicine
Verified email at wustl.edu
Title
Cited by
Cited by
Year
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
TP Sheahan, AC Sims, RL Graham, VD Menachery, LE Gralinski, ...
Science translational medicine 9 (396), eaal3653, 2017
18372017
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
D Pinto, YJ Park, M Beltramello, AC Walls, MA Tortorici, S Bianchi, ...
Nature 583 (7815), 290-295, 2020
17492020
Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease
ML Agostini, EL Andres, AC Sims, RL Graham, TP Sheahan, X Lu, ...
MBio 9 (2), 10.1128/mbio. 00221-18, 2018
13952018
Potently neutralizing and protective human antibodies against SARS-CoV-2
SJ Zost, P Gilchuk, JB Case, E Binshtein, RE Chen, JP Nkolola, A Schäfer, ...
Nature 584 (7821), 443-449, 2020
10542020
Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies
RE Chen, X Zhang, JB Case, ES Winkler, Y Liu, LA VanBlargan, J Liu, ...
Nature medicine 27 (4), 717-726, 2021
8942021
SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses
JS Turner, JA O’Halloran, E Kalaidina, W Kim, AJ Schmitz, JQ Zhou, T Lei, ...
Nature 596 (7870), 109-113, 2021
6612021
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19
MC Woodruff, RP Ramonell, DC Nguyen, KS Cashman, AS Saini, ...
Nature immunology 21 (12), 1506-1516, 2020
6272020
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, RE Chen, ...
Science 370 (6515), 426-431, 2020
5622020
A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies
AO Hassan, JB Case, ES Winkler, LB Thackray, NM Kafai, AL Bailey, ...
Cell 182 (3), 744-753. e4, 2020
5162020
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
MA Tortorici, M Beltramello, FA Lempp, D Pinto, HV Dang, LE Rosen, ...
Science 370 (6519), 950-957, 2020
5062020
A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2
AO Hassan, NM Kafai, IP Dmitriev, JM Fox, BK Smith, IB Harvey, RE Chen, ...
Cell 183 (1), 169-184. e13, 2020
4992020
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura, M Kiso, ...
Nature 603 (7902), 687-692, 2022
4912022
Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein
SJ Zost, P Gilchuk, RE Chen, JB Case, JX Reidy, A Trivette, RS Nargi, ...
Nature medicine 26 (9), 1422-1427, 2020
4712020
Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2
JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao, AS Kim, LM Bloyet, ...
Cell host & microbe 28 (3), 475-485. e5, 2020
3732020
The antigenic anatomy of SARS-CoV-2 receptor binding domain
W Dejnirattisai, D Zhou, HM Ginn, HME Duyvesteyn, P Supasa, JB Case, ...
Cell 184 (8), 2183-2200. e22, 2021
3532021
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
ES Winkler, P Gilchuk, J Yu, AL Bailey, RE Chen, Z Chong, SJ Zost, ...
Cell 184 (7), 1804-1820. e16, 2021
3162021
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
Nature microbiology 6 (10), 1233-1244, 2021
2472021
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains
RE Chen, ES Winkler, JB Case, ID Aziati, TL Bricker, A Joshi, TL Darling, ...
Nature 596 (7870), 103-108, 2021
2192021
Growth, detection, quantification, and inactivation of SARS-CoV-2
JB Case, AL Bailey, AS Kim, RE Chen, MS Diamond
Virology 548, 39-48, 2020
2172020
Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion
R Zang, JB Case, E Yutuc, X Ma, S Shen, MF Gomez Castro, Z Liu, ...
Proceedings of the National Academy of Sciences 117 (50), 32105-32113, 2020
2002020
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