Ragul Gowthaman
Ragul Gowthaman
Unknown affiliation
Verified email at umd.edu
Cited by
Cited by
Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1
L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ...
Molecular oncology 9 (7), 1406-1420, 2015
Sequence and structure signatures of cancer mutation hotspots in protein kinases
A Dixit, L Yi, R Gowthaman, A Torkamani, NJ Schork, GM Verkhivker
PloS one 4 (10), e7485, 2009
Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: implications for vaccine design
BG Pierce, ZY Keck, P Lau, C Fauvelle, R Gowthaman, TF Baumert, ...
Proceedings of the National Academy of Sciences 113 (45), E6946-E6954, 2016
Blind prediction of homo‐and hetero‐protein complexes: The CASP13‐CAPRI experiment
MF Lensink, G Brysbaert, N Nadzirin, S Velankar, RAG Chaleil, T Gerguri, ...
Proteins: Structure, Function, and Bioinformatics 87 (12), 1200-1221, 2019
Structural properties of non-traditional drug targets present new challenges for virtual screening
R Gowthaman, EJ Deeds, J Karanicolas
Journal of chemical information and modeling 53 (8), 2073-2081, 2013
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature Methods, 1-14, 2020
TCRmodel: high resolution modeling of T cell receptors from sequence
R Gowthaman, BG Pierce
Nucleic acids research 46 (W1), W396-W401, 2018
Peptide–MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC-and CD3-binding sites
S Rangarajan, Y He, Y Chen, MC Kerzic, B Ma, R Gowthaman, BG Pierce, ...
Journal of Biological Chemistry 293 (41), 15991-16005, 2018
DARC: mapping surface topography by ray-casting for effective virtual screening at protein interaction sites
R Gowthaman, SA Miller, S Rogers, J Khowsathit, L Lan, N Bai, ...
Journal of medicinal chemistry 59 (9), 4152-4170, 2016
DARC 2.0: improved docking and virtual screening at protein interaction sites
R Gowthaman, S Lyskov, J Karanicolas
PLOS one 10 (7), e0131612, 2015
TCR3d: The T cell receptor structural repertoire database
R Gowthaman, BG Pierce
Bioinformatics 35 (24), 5323-5325, 2019
Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins
L Lan, H Liu, AR Smith, C Appelman, J Yu, S Larsen, RT Marquez, X Wu, ...
BMC cancer 18 (1), 809, 2018
Computational screening of inhibitors for HIV-1 integrase using a receptor based pharmacophore model
J Jaganatharaja, R Gowthaman
Bioinformation 1 (4), 112, 2006
Database of neurodegenerative disorders
R Gowthaman, N Gowthaman, MK Rajangam, K Srinivasan
Bioinformation 2 (4), 153, 2007
Modeling of the potential coiled-coil structure of snapin protein and its interaction with SNARE complex
R Gowthaman, AJ Silvester, K Saranya, KSR Kanya, NR Archana
Bioinformation 1 (7), 269, 2006
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis
X Wu, G Gardashova, L Lan, S Han, C Zhong, RT Marquez, L Wei, ...
Communications biology 3 (1), 1-16, 2020
Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas
J Daniels, PG Doukas, MEM Escala, KG Ringbloom, DJH Shih, J Yang, ...
Nature communications 11 (1), 1-14, 2020
TeCK database: a comprehensive collection of telomeric and centromeric sequences with their associated proteins
R Gowthaman, S Krishnamoorthy, RD Nandakumar, V Ayyarappan
Bioinformation 2 (2), 73, 2007
CoV3D: a database of high resolution coronavirus protein structures
R Gowthaman, JD Guest, R Yin, J Adolf-Bryfogle, WR Schief, BG Pierce
Nucleic acids research 49 (D1), D282-D287, 2021
Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
D Wu, DT Gallagher, R Gowthaman, BG Pierce, RA Mariuzza
Nature Communications 11 (1), 1-12, 2020
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