| Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1 L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ... Molecular oncology 9 (7), 1406-1420, 2015 | 82 | 2015 |
| Sequence and structure signatures of cancer mutation hotspots in protein kinases A Dixit, L Yi, R Gowthaman, A Torkamani, NJ Schork, GM Verkhivker PloS one 4 (10), e7485, 2009 | 69 | 2009 |
| Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: implications for vaccine design BG Pierce, ZY Keck, P Lau, C Fauvelle, R Gowthaman, TF Baumert, ... Proceedings of the National Academy of Sciences 113 (45), E6946-E6954, 2016 | 48 | 2016 |
| Blind prediction of homo‐and hetero‐protein complexes: The CASP13‐CAPRI experiment MF Lensink, G Brysbaert, N Nadzirin, S Velankar, RAG Chaleil, T Gerguri, ... Proteins: Structure, Function, and Bioinformatics 87 (12), 1200-1221, 2019 | 30 | 2019 |
| Structural properties of non-traditional drug targets present new challenges for virtual screening R Gowthaman, EJ Deeds, J Karanicolas Journal of chemical information and modeling 53 (8), 2073-2081, 2013 | 30 | 2013 |
| Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature Methods, 1-14, 2020 | 28 | 2020 |
| TCRmodel: high resolution modeling of T cell receptors from sequence R Gowthaman, BG Pierce Nucleic acids research 46 (W1), W396-W401, 2018 | 24 | 2018 |
| Peptide–MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC-and CD3-binding sites S Rangarajan, Y He, Y Chen, MC Kerzic, B Ma, R Gowthaman, BG Pierce, ... Journal of Biological Chemistry 293 (41), 15991-16005, 2018 | 18 | 2018 |
| DARC: mapping surface topography by ray-casting for effective virtual screening at protein interaction sites R Gowthaman, SA Miller, S Rogers, J Khowsathit, L Lan, N Bai, ... Journal of medicinal chemistry 59 (9), 4152-4170, 2016 | 18 | 2016 |
| DARC 2.0: improved docking and virtual screening at protein interaction sites R Gowthaman, S Lyskov, J Karanicolas PLOS one 10 (7), e0131612, 2015 | 15 | 2015 |
| TCR3d: The T cell receptor structural repertoire database R Gowthaman, BG Pierce Bioinformatics 35 (24), 5323-5325, 2019 | 13 | 2019 |
| Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins L Lan, H Liu, AR Smith, C Appelman, J Yu, S Larsen, RT Marquez, X Wu, ... BMC cancer 18 (1), 809, 2018 | 10 | 2018 |
| Computational screening of inhibitors for HIV-1 integrase using a receptor based pharmacophore model J Jaganatharaja, R Gowthaman Bioinformation 1 (4), 112, 2006 | 8 | 2006 |
| Database of neurodegenerative disorders R Gowthaman, N Gowthaman, MK Rajangam, K Srinivasan Bioinformation 2 (4), 153, 2007 | 7 | 2007 |
| Modeling of the potential coiled-coil structure of snapin protein and its interaction with SNARE complex R Gowthaman, AJ Silvester, K Saranya, KSR Kanya, NR Archana Bioinformation 1 (7), 269, 2006 | 7 | 2006 |
| Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis X Wu, G Gardashova, L Lan, S Han, C Zhong, RT Marquez, L Wei, ... Communications biology 3 (1), 1-16, 2020 | 6 | 2020 |
| Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas J Daniels, PG Doukas, MEM Escala, KG Ringbloom, DJH Shih, J Yang, ... Nature communications 11 (1), 1-14, 2020 | 4 | 2020 |
| TeCK database: a comprehensive collection of telomeric and centromeric sequences with their associated proteins R Gowthaman, S Krishnamoorthy, RD Nandakumar, V Ayyarappan Bioinformation 2 (2), 73, 2007 | 4 | 2007 |
| CoV3D: a database of high resolution coronavirus protein structures R Gowthaman, JD Guest, R Yin, J Adolf-Bryfogle, WR Schief, BG Pierce Nucleic acids research 49 (D1), D282-D287, 2021 | 3 | 2021 |
| Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen D Wu, DT Gallagher, R Gowthaman, BG Pierce, RA Mariuzza Nature Communications 11 (1), 1-12, 2020 | 3 | 2020 |
