| The αvβ1 integrin plays a critical in vivo role in tissue fibrosis NI Reed, H Jo, C Chen, K Tsujino, TD Arnold, WF DeGrado, D Sheppard Science translational medicine 7 (288), 288ra79-288ra79, 2015 | 310 | 2015 |
| Development of α-helical calpain probes by mimicking a natural protein–protein interaction H Jo, N Meinhardt, Y Wu, S Kulkarni, X Hu, KE Low, PL Davies, ... Journal of the American Chemical Society 134 (42), 17704-17713, 2012 | 272 | 2012 |
| Alteration of the oxygen-dependent reactivity of de novo Due Ferri proteins AJ Reig, MM Pires, RA Snyder, Y Wu, H Jo, DW Kulp, SE Butch, ... Nature chemistry 4 (11), 900-906, 2012 | 135 | 2012 |
| Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus J Wang, C Ma, J Wang, H Jo, B Canturk, G Fiorin, LH Pinto, RA Lamb, ... Journal of medicinal chemistry 56 (7), 2804-2812, 2013 | 118 | 2013 |
| Blue fluorescent amino acid for biological spectroscopy and microscopy MR Hilaire, IA Ahmed, CW Lin, H Jo, WF DeGrado, F Gai Proceedings of the National Academy of Sciences 114 (23), 6005-6009, 2017 | 110 | 2017 |
| Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 … Y Wu, B Canturk, H Jo, C Ma, E Gianti, ML Klein, LH Pinto, RA Lamb, ... Journal of the American Chemical Society 136 (52), 17987-17995, 2014 | 96 | 2014 |
| Structural polymorphism of Alzheimer’s β-amyloid fibrils as controlled by an E22 switch: A solid-state NMR study MR Elkins, T Wang, M Nick, H Jo, T Lemmin, SB Prusiner, WF DeGrado, ... Journal of the American Chemical Society 138 (31), 9840-9852, 2016 | 90 | 2016 |
| Inhibition of integrin α2β1 ameliorates glomerular injury CM Borza, Y Su, X Chen, L Yu, S Mont, S Chetyrkin, P Voziyan, ... Journal of the American Society of Nephrology 23 (6), 1027-1038, 2012 | 89 | 2012 |
| Platelet factor 4 activity against P. falciparum and its translation to nonpeptidic mimics as antimalarials MS Love, MG Millholland, S Mishra, S Kulkarni, KB Freeman, W Pan, ... Cell host & microbe 12 (6), 815-823, 2012 | 87 | 2012 |
| Using thioamides to site-specifically interrogate the dynamics of hydrogen bond formation in β-sheet folding RM Culik, H Jo, WF DeGrado, F Gai Journal of the American Chemical Society 134 (19), 8026-8029, 2012 | 86 | 2012 |
| Water distribution, dynamics, and interactions with Alzheimer’s β-amyloid fibrils investigated by solid-state NMR T Wang, H Jo, WF DeGrado, M Hong Journal of the American Chemical Society 139 (17), 6242-6252, 2017 | 83 | 2017 |
| Asymmetric Total Synthesis of (+)-Brefeldin A from (S)-Lactate by Triple Chirality Transfer Process and Nitrile Oxide Cycloaddition,1 D Kim, J Lee, PJ Shim, JI Lim, H Jo, S Kim The Journal of Organic Chemistry 67 (3), 764-771, 2002 | 78 | 2002 |
| Highly stereoselective and efficient total synthesis of (+)-laurencin S Baek, H Jo, H Kim, H Kim, S Kim, D Kim Organic Letters 7 (1), 75-77, 2005 | 76 | 2005 |
| Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment DT Moore, P Nygren, H Jo, K Boesze-Battaglia, JS Bennett, WF DeGrado Proceedings of the National Academy of Sciences 109 (3), 793-798, 2012 | 74 | 2012 |
| Discovery of Potent Small-Molecule Inhibitors of Multidrug-Resistant Plasmodium falciparum Using a Novel Miniaturized High-Throughput Luciferase-Based Assay E Lucumi, C Darling, H Jo, AD Napper, R Chandramohanadas, N Fisher, ... Antimicrobial agents and chemotherapy 54 (9), 3597-3604, 2010 | 61 | 2010 |
| Pharmacologic blockade of αvβ1 integrin ameliorates renal failure and fibrosis in vivo Y Chang, WL Lau, H Jo, K Tsujino, L Gewin, NI Reed, A Atakilit, ... Journal of the American Society of Nephrology 28 (7), 1998-2005, 2017 | 59 | 2017 |
| Selective incorporation of nitrile-based infrared probes into proteins via cysteine alkylation H Jo, RM Culik, IV Korendovych, WF DeGrado, F Gai Biochemistry 49 (49), 10354-10356, 2010 | 57 | 2010 |
| Inhibitor binding mode and allosteric regulation of Na+-glucose symporters P Bisignano, C Ghezzi, H Jo, NF Polizzi, T Althoff, C Kalyanaraman, ... Nature communications 9 (1), 5245, 2018 | 44 | 2018 |
| Stapled Voltage-Gated Calcium Channel (CaV) α-Interaction Domain (AID) Peptides Act As Selective Protein–Protein Interaction Inhibitors of CaV Function F Findeisen, M Campiglio, H Jo, F Abderemane-Ali, CH Rumpf, L Pope, ... ACS chemical neuroscience 8 (6), 1313-1326, 2017 | 41 | 2017 |
| Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma A Sundaram, C Chen, A Khalifeh-Soltani, A Atakilit, X Ren, W Qiu, H Jo, ... The Journal of clinical investigation 127 (1), 365-374, 2017 | 32 | 2017 |
