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| Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase J Mitchell, P Paul, HJ Chen, A Morris, M Payling, M Falchi, J Habgood, ... Proceedings of the National Academy of Sciences 107 (16), 7556-7561, 2010 | 298 | 2010 |
| Characterization of the properties of a novel mutation in VAPB in familial amyotrophic lateral sclerosis HJ Chen, G Anagnostou, A Chai, J Withers, A Morris, J Adhikaree, ... Journal of Biological Chemistry 285 (51), 40266-40281, 2010 | 208 | 2010 |
| The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis HJ Chen, JC Mitchell, S Novoselov, J Miller, AL Nishimura, EL Scotter, ... Brain 139 (5), 1417-1432, 2016 | 170 | 2016 |
| Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis BN Smith, SD Topp, C Fallini, H Shibata, HJ Chen, C Troakes, A King, ... Science translational medicine 9 (388), eaad9157, 2017 | 150 | 2017 |
| Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression PS Sharp, MT Akbar, S Bouri, A Senda, K Joshi, HJ Chen, DS Latchman, ... Neurobiology of disease 30 (1), 42-55, 2008 | 132 | 2008 |
| C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity YB Lee, P Baskaran, J Gomez-Deza, HJ Chen, AL Nishimura, BN Smith, ... Human molecular genetics 26 (24), 4765-4777, 2017 | 89 | 2017 |
| RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy HJ Chen, SD Topp, HS Hui, E Zacco, M Katarya, C McLoughlin, A King, ... Brain 142 (12), 3753-3770, 2019 | 83 | 2019 |
| ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function M de Majo, SD Topp, BN Smith, AL Nishimura, HJ Chen, AS Gkazi, ... Neurobiology of aging 71, 266. e1-266. e10, 2018 | 75 | 2018 |
| Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells AL Nishimura, C Shum, EL Scotter, A Abdelgany, V Sardone, J Wright, ... PloS one 9 (3), e91269, 2014 | 60 | 2014 |
| Renin-angiotensin system polymorphisms in Taiwanese primary vesicoureteral reflux KP Liu, CY Lin, HJ Chen, CF Wei, GJ Lee-Chen Podiatry Nephron 19, 594-601, 2004 | 24 | 2004 |
| Mechanisms of TDP-43 proteinopathy onset and propagation HJ Chen, JC Mitchell International Journal of Molecular Sciences 22 (11), 6004, 2021 | 15 | 2021 |
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| Endoplasmic reticulum (ER) stress in amyotrophic lateral sclerosis (ALS) HJ Chen, J De Belleroche Endoplasmic reticulum stress in health and disease, 323-337, 2012 | 6 | 2012 |
| A novel putative familial ALS locus on chromosome 12: D-amino acid oxidase JS De Belleroche, J Mitchell, P Paul, HJ Chen, A Morris, A Hajitou, ... Neurology 72 (11), A114-A114, 2009 | 2 | 2009 |
