| Dual plasmepsin-targeting antimalarial agents disrupt multiple stages of the malaria parasite life cycle P Favuzza, M de Lera Ruiz, JK Thompson, T Triglia, A Ngo, RWJ Steel, ... Cell host & microbe 27 (4), 642-658. e12, 2020 | 104 | 2020 |
| Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen AM Dreyer, H Matile, P Papastogiannidis, J Kamber, P Favuzza, TS Voss, ... The Journal of Immunology 188 (12), 6225-6237, 2012 | 75 | 2012 |
| Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody P Favuzza, E Guffart, M Tamborrini, B Scherer, AM Dreyer, AC Rufer, ... Elife 6, e20383, 2017 | 64 | 2017 |
| Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA P Favuzza, S Blaser, AM Dreyer, G Riccio, M Tamborrini, R Thoma, ... Malaria journal 15, 1-14, 2016 | 25 | 2016 |
| Vaccination with virosomally formulated recombinant CyRPA elicits protective antibodies against Plasmodium falciparum parasites in preclinical in vitro and in vivo … M Tamborrini, J Hauser, A Schäfer, M Amacker, P Favuzza, K Kyungtak, ... NPJ vaccines 5 (1), 9, 2020 | 21 | 2020 |
| Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 MA Lowe, A Cardenas, JP Valentin, Z Zhu, J Abendroth, JL Castro, ... Journal of medicinal chemistry 65 (20), 14121-14143, 2022 | 15 | 2022 |
| Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax AN Hodder, J Christensen, S Scally, T Triglia, A Ngo, RW Birkinshaw, ... Structure 30 (7), 947-961. e6, 2022 | 13 | 2022 |
| Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity BL Bailey, W Nguyen, A Ngo, CD Goodman, MR Gancheva, P Favuzza, ... Bioorganic Chemistry 115, 105244, 2021 | 12 | 2021 |
| Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity TD Ashton, A Ngo, P Favuzza, HE Bullen, MR Gancheva, O Romeo, ... Bioorganic Chemistry 117, 105359, 2021 | 11 | 2021 |
| Generation of monoclonal antibodies against native viral proteins using antigen-expressing mammalian cells for mouse immunization N Rose, CA Pinho-Nascimento, A Ruggieri, P Favuzza, M Tamborrini, ... BMC biotechnology 16, 1-11, 2016 | 10 | 2016 |
| Optimization of 2, 3-dihydroquinazolinone-3-carboxamides as antimalarials targeting PfATP4 TD Ashton, MG Dans, P Favuzza, A Ngo, AM Lehane, X Zhang, D Qiu, ... Journal of Medicinal Chemistry 66 (5), 3540-3565, 2023 | 5 | 2023 |
| The invention of WM382, a highly potent PMIX/X dual inhibitor toward the treatment of malaria M de Lera Ruiz, P Favuzza, Z Guo, L Zhao, B Hu, Z Lei, D Zhan, ... ACS Medicinal Chemistry Letters 13 (11), 1745-1754, 2022 | 5 | 2022 |
| 7-N-Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc1 Complex W Nguyen, MG Dans, I Currie, JK Awalt, BL Bailey, C Lumb, A Ngo, ... ACS Infectious Diseases 9 (3), 668-691, 2023 | 4 | 2023 |
| Substrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity LW Richardson, TD Ashton, MG Dans, N Nguyen, P Favuzza, T Triglia, ... ChemMedChem 17 (18), e202200306, 2022 | 4 | 2022 |
| Cysteine-Rich Protective Antigen (CyRPA) as promising blood-stage candidate protein for inclusion in a malaria subunit vaccine P Favuzza, AM Dreyer, S Wittlin, H Matile, G Pluschke Malaria Journal 11, 1-2, 2012 | 3 | 2012 |
| Passive immunoprotection of G Pluschke, J Kamber, P Favuzza, TS Voss, SAM Dreyer, H Matile, ... Plasmodium falciparum, 2012 | 2 | 2012 |
| The essential malaria protein PfCyRPA targets glycans to invade erythrocytes CJ Day, P Favuzza, S Bielfeld, T Haselhorst, L Seefeldt, J Hauser, ... Cell Reports 43 (4), 2024 | | 2024 |
| Antimalarial agents M de Lera Ruiz, P Favuzza, Z Guo, B Hu, MJ Kelly III, Z Lei, JA McCauley, ... US Patent App. 17/795,349, 2023 | | 2023 |
| Antimalarial agents JA McCauley, AF Cowman, M de Lera Ruiz, P Favuzza, Z Guo, B Hu, ... US Patent App. 17/633,655, 2022 | | 2022 |
| Basis for drug selectivity of plasmepsin IX and X inhibition for Plasmodium falciparum and vivax A Cowman, A Hodder, J Christensen, S Scally, T Triglia, A Ngo, ... | | 2021 |
