| Translational dysregulation in cancer: eIF4A isoforms and sequence determinants of eIF4A dependence F Raza, JA Waldron, JL Quesne Biochemical Society transactions 43 (6), 1227-1233, 2015 | 63 | 2015 |
| MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ... Cancer discovery 11 (5), 1228-1247, 2021 | 53 | 2021 |
| mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity JA Waldron, DC Tack, LE Ritchey, SL Gillen, A Wilczynska, E Turro, ... Genome biology 20, 1-23, 2019 | 47 | 2019 |
| eIF4A alleviates the translational repression mediated by classical secondary structures more than by G-quadruplexes JA Waldron, F Raza, J Le Quesne Nucleic acids research 46 (6), 3075-3087, 2018 | 41 | 2018 |
| The 3'-5'exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs BP Towler, CI Jones, SC Viegas, P Apura, JA Waldron, SK Smalley, ... RNA biology 12 (7), 728-741, 2015 | 39 | 2015 |
| The 5′-3′ exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277–3p in Drosophila wing imaginal discs CI Jones, DP Grima, JA Waldron, S Jones, HN Parker, SF Newbury RNA biology 10 (8), 1345-1355, 2013 | 36 | 2013 |
| Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper JA Waldron, CI Jones, BP Towler, AL Pashler, DP Grima, S Hebbes, ... Biology open 4 (5), 649-660, 2015 | 32 | 2015 |
| A novel role for the 3′-5′ exoribonuclease Dis3L2 in controlling cell proliferation and tissue growth BP Towler, CI Jones, KL Harper, JA Waldron, SF Newbury RNA biology 13 (12), 1286-1299, 2016 | 30 | 2016 |
| The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction EM Smith, NEH Benbahouche, K Morris, A Wilczynska, S Gillen, ... Nucleic Acids Research 49 (1), 458-478, 2021 | 24 | 2021 |
| The roles of miRNAs in wing imaginal disc development in Drosophila JA Waldron, SF Newbury Biochemical Society Transactions 40 (4), 891-895, 2012 | 17 | 2012 |
| Codon optimality in cancer SL Gillen, JA Waldron, M Bushell Oncogene 40 (45), 6309-6320, 2021 | 15 | 2021 |
| eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation T Schmidt, A Dabrowska, JA Waldron, K Hodge, G Koulouras, ... Nucleic Acids Research 51 (4), 1859-1879, 2023 | 11 | 2023 |
| The role of the exoribonuclease Pacman/Xrn1 in wing development in Drosophila JA Waldron University of Brighton, 2014 | 2 | 2014 |
| Translation efficiency driven by CNOT3 subunit of the CCR4-NOT complex promotes leukemogenesis M Ghashghaei, Y Liu, J Ettles, G Bombaci, N Ramkumar, Z Liu, L Escano, ... Nature Communications 15 (1), 2340, 2024 | | 2024 |
| The eIF4A2 negative regulator of mRNA translation promotes extracellular matrix deposition to accelerate hepatocellular carcinoma initiation M Moore, L Pardo-Fernandez, L Mitchell, T Schmidt, JA Waldron, S May, ... bioRxiv, 2023.08. 16.553544, 2023 | | 2023 |
| Optimisation of sample preparation from primary mouse tissue to maintain RNA integrity for methods examining translational control J Munro, SL Gillen, L Mitchell, S Laing, SA Karim, CJ Rink, JA Waldron, ... Cancers 15 (15), 3985, 2023 | | 2023 |
| eIF4A1 is essential for reprogramming the translational landscape of Wnt-driven colorectal cancers JA Waldron, G Kanellos, RCL Smith, JRP Knight, J Munro, C Alexandrou, ... bioRxiv, 2023.11. 10.566546, 2023 | | 2023 |
Christopher Iain JonesBrighton and Sussex Medical SchoolVerified email at bsms.ac.uk
