| Amyloid beta: structure, biology and structure-based therapeutic development G Chen, T Xu, Y Yan, Y Zhou, Y Jiang, K Melcher, HE Xu Acta Pharmacologica Sinica 38 (9), 1205-1235, 2017 | 1614 | 2017 |
| Molecular recognition of fatty acids by peroxisome proliferator–activated receptors HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ... Molecular cell 3 (3), 397-403, 1999 | 1494 | 1999 |
| A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ... Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001 | 1447 | 2001 |
| Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ... Science 368 (6498), 1499-1504, 2020 | 1190 | 2020 |
| Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ... Cell 110 (1), 93-105, 2002 | 993 | 2002 |
| Androgen receptor: structure, role in prostate cancer and drug discovery MH Tan, J Li, HE Xu, K Melcher, E Yong Acta Pharmacologica Sinica 36 (1), 3-23, 2015 | 957 | 2015 |
| Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ... Nature 523 (7562), 561-567, 2015 | 829 | 2015 |
| DWARF 53 acts as a repressor of strigolactone signalling in rice L Jiang, X Liu, G Xiong, H Liu, F Chen, L Wang, X Meng, G Liu, H Yu, ... Nature 504 (7480), 401-405, 2013 | 787 | 2013 |
| Structural features for functional selectivity at serotonin receptors D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ... Science 340 (6132), 615-619, 2013 | 787 | 2013 |
| Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ... Nature 415 (6873), 813-817, 2002 | 757 | 2002 |
| A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors K Melcher, LM Ng, XE Zhou, FF Soon, Y Xu, KM Suino-Powell, SY Park, ... Nature 462 (7273), 602-608, 2009 | 753 | 2009 |
| Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors RT Gampe, VG Montana, MH Lambert, AB Miller, RK Bledsoe, MV Milburn, ... Molecular cell 5 (3), 545-555, 2000 | 740 | 2000 |
| Structural basis for molecular recognition of folic acid by folate receptors C Chen, J Ke, XE Zhou, W Yi, JS Brunzelle, J Li, EL Yong, HE Xu, ... Nature 500 (7463), 486-489, 2013 | 694 | 2013 |
| Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ... Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001 | 678 | 2001 |
| FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ... Science 331 (6024), 1621-1624, 2011 | 639 | 2011 |
| Identification of a physiologically relevant endogenous ligand for PPARα in liver MV Chakravarthy, IJ Lodhi, L Yin, RRV Malapaka, HE Xu, J Turk, ... Cell 138 (3), 476-488, 2009 | 622 | 2009 |
| Structural basis for molecular recognition at serotonin receptors C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ... Science 340 (6132), 610-614, 2013 | 597 | 2013 |
| Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ... Nature 472 (7344), 486-490, 2011 | 594 | 2011 |
| Peroxisome proliferator-activated receptors: from genes to physiology. SA Kliewer, HE Xu, MH Lambert, TM Willson Recent progress in hormone research 56, 239-263, 2001 | 553 | 2001 |
| Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases FF Soon, LM Ng, XE Zhou, GM West, A Kovach, MHE Tan, ... Science 335 (6064), 85-88, 2012 | 540 | 2012 |
Karsten MelcherVan Andel InstituteVerified email at vai.org
