H Eric Xu (徐华强), Professor and Director
H Eric Xu (徐华强), Professor and Director
Key Lab of Receptor Research, Shanghai Institute of Materia Medica, CAS; VARI/GlaxoWellcome/GSK
Verified email at
Cited by
Cited by
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors
HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ...
Molecular cell 3 (3), 397-403, 1999
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ...
Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001
Amyloid beta: structure, biology and structure-based therapeutic development
G Chen, T Xu, Y Yan, Y Zhou, Y Jiang, K Melcher, HE Xu
Acta Pharmacologica Sinica 38 (9), 1205-1235, 2017
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ...
Science 368 (6498), 1499-1504, 2020
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ...
Cell 110 (1), 93-105, 2002
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ...
Nature 523 (7562), 561-567, 2015
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα
HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ...
Nature 415 (6873), 813-817, 2002
Androgen receptor: structure, role in prostate cancer and drug discovery
MH Tan, J Li, HE Xu, K Melcher, E Yong
Acta Pharmacologica Sinica 36 (1), 3-23, 2015
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
RT Gampe Jr, VG Montana, MH Lambert, AB Miller, RK Bledsoe, ...
Molecular cell 5 (3), 545-555, 2000
Structural features for functional selectivity at serotonin receptors
D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ...
Science 340 (6132), 615-619, 2013
A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors
K Melcher, LM Ng, XE Zhou, FF Soon, Y Xu, KM Suino-Powell, SY Park, ...
Nature 462 (7273), 602-608, 2009
DWARF 53 acts as a repressor of strigolactone signalling in rice
L Jiang, X Liu, G Xiong, H Liu, F Chen, L Wang, X Meng, G Liu, H Yu, ...
Nature 504 (7480), 401-405, 2013
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ...
Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001
Structural basis for molecular recognition of folic acid by folate receptors
C Chen, J Ke, XE Zhou, W Yi, JS Brunzelle, J Li, EL Yong, HE Xu, ...
Nature 500 (7463), 486-489, 2013
Identification of a physiologically relevant endogenous ligand for PPARα in liver
MV Chakravarthy, IJ Lodhi, L Yin, RRV Malapaka, HE Xu, J Turk, ...
Cell 138 (3), 476-488, 2009
FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis
S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ...
Science 331 (6024), 1621-1624, 2011
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ...
Nature 472 (7344), 486-490, 2011
Peroxisome proliferator-activated receptors: from genes to physiology.
SA Kliewer, HE Xu, MH Lambert, TM Willson
Recent progress in hormone research 56, 239-263, 2001
Structural basis for molecular recognition at serotonin receptors
C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ...
Science 340 (6132), 610-614, 2013
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans
DL Motola, CL Cummins, V Rottiers, KK Sharma, T Li, Y Li, ...
Cell 124 (6), 1209-1223, 2006
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