| Identification of host proteins required for HIV infection through a functional genomic screen AL Brass, DM Dykxhoorn, Y Benita, N Yan, A Engelman, RJ Xavier, ... science 319 (5865), 921-926, 2008 | 1765 | 2008 |
| Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases F Dyda, AB Hickman, TM Jenkins, A Engelman, R Craigie, DR Davies Science 266 (5193), 1981-1986, 1994 | 1057 | 1994 |
| HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer A Engelman, K Mizuuchi, R Craigie Cell 67 (6), 1211-1221, 1991 | 894 | 1991 |
| Retroviral intasome assembly and inhibition of DNA strand transfer S Hare, SS Gupta, E Valkov, A Engelman, P Cherepanov Nature 464 (7286), 232-236, 2010 | 792 | 2010 |
| The structural biology of HIV-1: mechanistic and therapeutic insights A Engelman, P Cherepanov Nature Reviews Microbiology 10 (4), 279-290, 2012 | 717 | 2012 |
| Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro A Engelman, R Craigie Journal of virology 66 (11), 6361-6369, 1992 | 673 | 1992 |
| LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration MC Shun, NK Raghavendra, N Vandegraaff, JE Daigle, S Hughes, ... Genes & development 21 (14), 1767-1778, 2007 | 574 | 2007 |
| Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication A Engelman, G Englund, JM Orenstein, MA Martin, R Craigie Journal of virology 69 (5), 2729-2736, 1995 | 541 | 1995 |
| Flexible use of nuclear import pathways by HIV-1 KE Lee, Z Ambrose, TD Martin, I Oztop, A Mulky, JG Julias, N Vandegraaff, ... Cell host & microbe 7 (3), 221-233, 2010 | 533 | 2010 |
| Haematopoietic stem and progenitor cells from human pluripotent stem cells R Sugimura, DK Jha, A Han, C Soria-Valles, EL Da Rocha, YF Lu, ... Nature 545 (7655), 432-438, 2017 | 491 | 2017 |
| Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 P Cherepanov, ALB Ambrosio, S Rahman, T Ellenberger, A Engelman Proceedings of the National Academy of Sciences 102 (48), 17308-17313, 2005 | 480 | 2005 |
| Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding. FD Bushman, A Engelman, I Palmer, P Wingfield, R Craigie Proceedings of the National Academy of Sciences 90 (8), 3428-3432, 1993 | 467 | 1993 |
| Identification of discrete functional domains of HIV‐1 integrase and their organization within an active multimeric complex. A Engelman, FD Bushman, R Craigie The EMBO Journal 12 (8), 3269-3275, 1993 | 451 | 1993 |
| Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity JK Nuñez, ASY Lee, A Engelman, JA Doudna Nature 519 (7542), 193-198, 2015 | 416 | 2015 |
| Solution structure of the DNA binding domain of HIV-1 integrase PJ Lodi, JA Ernst, J Kuszewski, AB Hickman, A Engelman, R Craigie, ... Biochemistry 34 (31), 9826-9833, 1995 | 399 | 1995 |
| A Soluble Active Mutant of HIV-1 Integrase: INVOLVEMENT OF BOTH THE CORE AND CARBOXYL-TERMINAL DOMAINS IN MULTIMERIZATION (∗) TM Jenkins, A Engelman, R Ghirlando, R Craigie Journal of Biological Chemistry 271 (13), 7712-7718, 1996 | 374 | 1996 |
| Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration JL Mbisa, R Barr, JA Thomas, N Vandegraaff, IJ Dorweiler, ... Journal of virology 81 (13), 7099-7110, 2007 | 340 | 2007 |
| Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase P Cherepanov, E Devroe, PA Silver, A Engelman Journal of Biological Chemistry 279 (47), 48883-48892, 2004 | 328 | 2004 |
| The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication A Engelman, P Cherepanov PLoS pathogens 4 (3), e1000046, 2008 | 305 | 2008 |
| Critical contacts between HIV‐1 integrase and viral DNA identified by structure‐based analysis and photo‐crosslinking TM Jenkins, D Esposito, A Engelman, R Craigie The EMBO Journal, 1997 | 302 | 1997 |
