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Phillip Hawkins
Phillip Hawkins
Group Leader, Babraham Institute
Verified email at babraham.ac.uk - Homepage
Title
Cited by
Cited by
Year
Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase B
D Stokoe, LR Stephens, T Copeland, PRJ Gaffney, CB Reese, GF Painter, ...
Science 277 (5325), 567-570, 1997
16371997
Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B
L Stephens, K Anderson, D Stokoe, H Erdjument-Bromage, GF Painter, ...
Science 279 (5351), 710-714, 1998
14271998
PI3K signalling: the path to discovery and understanding
B Vanhaesebroeck, L Stephens, P Hawkins
Nature reviews Molecular cell biology 13 (3), 195-203, 2012
10742012
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits
L Stephens, A Smrcka, FT Cooke, TR Jackson, PC Sternweis, PT Hawkins
Cell 77 (1), 83-93, 1994
7911994
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase γ
ME Pacold, S Suire, O Perisic, S Lara-Gonzalez, CT Davis, EH Walker, ...
Cell 103 (6), 931-944, 2000
7752000
The Gβγ sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
LR Stephens, A Eguinoa, H Erdjument-Bromage, M Lui, F Cooke, ...
Cell 89 (1), 105-114, 1997
7291997
Signalling through Class I PI3Ks in mammalian cells
PT Hawkins, KE Anderson, K Davidson, LR Stephens
Biochemical Society Transactions 34 (5), 647-662, 2006
7162006
PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase
PT Hawkins, A Eguinoa, RG Qiu, D Stokoe, FT Cooke, R Walters, ...
Current Biology 5 (4), 393-403, 1995
7051995
P-Rex1, a PtdIns (3, 4, 5) P3-and Gβγ-regulated guanine-nucleotide exchange factor for Rac
HCE Welch, WJ Coadwell, CD Ellson, GJ Ferguson, SR Andrews, ...
Cell 108 (6), 809-821, 2002
6692002
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ...
Science 342 (6160), 866-871, 2013
6242013
Agonist-stimulated synthesis of phosphatidylinositol (3, 4, 5)-trisphosphate: a new intracellular signalling system?
LR Stephens, TR Jackson, PT Hawkins
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1179 (1), 27-75, 1993
6221993
Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4, 5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones
JA Creba, CP Downes, PT Hawkins, G Brewster, RH Michell, CJ Kirk
Biochemical Journal 212 (3), 733-747, 1983
6221983
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
CD Nobes, P Hawkins, L Stephens, A Hall
Journal of cell science 108 (1), 225-233, 1995
5921995
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
S Wennström, P Hawkins, F Cooke, K Hara, K Yonezawa, M Kasuga, ...
Current Biology 4 (5), 385-393, 1994
5521994
PI3K signalling in inflammation
PT Hawkins, LR Stephens
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
5232015
Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
KE Anderson, J Coadwell, LR Stephens, PT Hawkins
Current Biology 8 (12), 684-691, 1998
5041998
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox).
SLR Ellson CD, Gobert-Gosse S, Anderson KE, Davidson K, Erdjument-Bromage H ...
nature cell biology 3 (7), 679-82, 2001
4862001
Phosphoinositide 3-kinase-dependent activation of Rac
HCE Welch, WJ Coadwell, LR Stephens, PT Hawkins
FEBS letters 546 (1), 93-97, 2003
4392003
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils
AM Condliffe, K Davidson, KE Anderson, CD Ellson, T Crabbe, ...
Blood 106 (4), 1432-1440, 2005
3832005
Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices
S Krugmann, KE Anderson, SH Ridley, N Risso, A McGregor, J Coadwell, ...
Molecular cell 9 (1), 95-108, 2002
3542002
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