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Thomas Iskratsch
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Appreciating force and shape—the rise of mechanotransduction in cell biology
T Iskratsch, H Wolfenson, MP Sheetz
Nature reviews Molecular cell biology 15 (12), 825-833, 2014
7982014
Finding the weakest link–exploring integrin-mediated mechanical molecular pathways
P Roca-Cusachs, T Iskratsch, MP Sheetz
Journal of cell science 125 (13), 3025-3038, 2012
3102012
Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices
H Wolfenson, G Meacci, S Liu, MR Stachowiak, T Iskratsch, S Ghassemi, ...
Nature cell biology 18 (1), 33-42, 2016
2002016
Specificity analysis of lectins and antibodies using remodeled glycoproteins
T Iskratsch, A Braun, K Paschinger, IBH Wilson
Analytical Biochemistry 386 (2), 133-146, 2009
1532009
Cardiomyocytes sense matrix rigidity through a combination of muscle and non-muscle myosin contractions
P Pandey, W Hawkes, J Hu, WV Megone, J Gautrot, N Anilkumar, ...
Developmental cell 44 (3), 326-336. e3, 2018
1352018
Formin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenance
T Iskratsch, S Lange, J Dwyer, AL Kho, C Remedios, E Ehler
Journal of Cell Biology 191 (6), 1159-1172, 2010
1262010
FHOD1 is needed for directed forces and adhesion maturation during cell spreading and migration
T Iskratsch, CH Yu, A Mathur, S Liu, V Stévenin, J Dwyer, J Hone, E Ehler, ...
Developmental cell 27 (5), 545-559, 2013
1192013
Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells
E Tabdanov, S Gondarenko, S Kumari, A Liapis, ML Dustin, MP Sheetz, ...
Integrative biology 7 (10), 1272-1284, 2015
992015
Polymer fiber-based models of connective tissue repair and healing
NM Lee, C Erisken, T Iskratsch, M Sheetz, WN Levine, HH Lu
Biomaterials 112, 303-312, 2017
942017
α-Actinin links extracellular matrix rigidity-sensing contractile units with periodic cell-edge retractions
G Meacci, H Wolfenson, S Liu, MR Stachowiak, T Iskratsch, A Mathur, ...
Molecular biology of the cell 27 (22), 3471-3479, 2016
892016
Early events in cell spreading as a model for quantitative analysis of biomechanical events
H Wolfenson, T Iskratsch, MP Sheetz
Biophysical journal 107 (11), 2508-2514, 2014
752014
Two distinct phosphorylation events govern the function of muscle FHOD3
T Iskratsch, S Reijntjes, J Dwyer, P Toselli, IR Dégano, I Dominguez, ...
Cellular and Molecular Life Sciences 70, 893-908, 2013
562013
Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and-861
AR Pedrosa, N Bodrug, J Gomez-Escudero, EP Carter, LE Reynolds, ...
Cancer research 79 (17), 4371-4386, 2019
552019
Probing the nanoscale organisation and multivalency of cell surface receptors: DNA origami nanoarrays for cellular studies with single-molecule control
W Hawkes, D Huang, P Reynolds, L Hammond, M Ward, N Gadegaard, ...
Faraday Discussions 219, 203-219, 2019
462019
Mix and (mis-) match–The mechanosensing machinery in the changing environment of the developing, healthy adult and diseased heart
M Ward, T Iskratsch
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (3), 118436, 2020
452020
Endoplasmic Spreading Requires Coalescence of Vimentin Intermediate Filaments at Force-Bearing Adhesions
CD Lynch, AM Lazar, T Iskratsch, X Zhang, MP Sheetz
Molecular Biology of the Cell, 2012
442012
Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing
E Marhuenda, C Fabre, C Zhang, M Martin-Fernandez, T Iskratsch, ...
Journal of experimental & clinical cancer research 40 (1), 139, 2021
412021
N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading
X Zhang, SW Moore, T Iskratsch, MP Sheetz
Journal of cell science 127 (7), 1394-1405, 2014
382014
Mammalian cells contain a second nucleocytoplasmic hexosaminidase
M Gutternigg, D Rendić, R Voglauer, T Iskratsch, IBH Wilson
Biochemical Journal 419 (1), 83-90, 2009
362009
Costameres, dense plaques and podosomes: the cell matrix adhesions in cardiovascular mechanosensing
B Sit, D Gutmann, T Iskratsch
Journal of muscle research and cell motility 40, 197-209, 2019
342019
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