Medium-scale preparation of useful metabolites of aromatic compounds via whole-cell fermentation with recombinant organisms MA Endoma, VP Bui, J Hansen, T Hudlicky Organic process research & development 6 (4), 525-532, 2002 | 100 | 2002 |
Improved Synthesis of Buprenorphine from Thebaine and/or Oripavine via Palladium‐Catalyzed N‐Demethylation/Acylation and/or Concomitant O‐Demethylation A Machara, L Werner, MA Endoma‐Arias, DP Cox, T Hudlicky Advanced Synthesis & Catalysis 354 (4), 613-626, 2012 | 56 | 2012 |
Enantioselective total synthesis and biological evaluation of (+)-kibdelone A and a tetrahydroxanthone analogue DK Winter, MA Endoma-Arias, T Hudlicky, JA Beutler, JA Porco Jr The Journal of organic chemistry 78 (15), 7617-7626, 2013 | 55 | 2013 |
General method of synthesis for naloxone, naltrexone, nalbuphone, and nalbuphine by the reaction of Grignard reagents with an oxazolidine derived from oxymorphone MAA Endoma‐Arias, DP Cox, T Hudlicky Advanced Synthesis & Catalysis 355 (9), 1869-1873, 2013 | 48 | 2013 |
Chemoenzymatic Formal Total Synthesis of ent‐Codeine and Other Morphinans via Nitrone Cycloadditions and/or Radical Cyclizations. Comparison of Strategies for Control of C‐9/C … MAA Endoma‐Arias, JR Hudlicky, R Simionescu, T Hudlicky Advanced Synthesis & Catalysis 356 (2‐3), 333-339, 2014 | 41 | 2014 |
Chemoenzymatic Total Synthesis of ent-Oxycodone: Second-, Third-, and Fourth-Generation Strategies M Makarova, MAA Endoma-Arias, HE Dela Paz, R Simionescu, ... Journal of the American Chemical Society 141 (27), 10883-10904, 2019 | 35 | 2019 |
Unexpected N‐Demethylation of Oxymorphone and Oxycodone N‐Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone L Werner, M Wernerova, A Machara, MA Endoma‐Arias, J Duchek, ... Advanced Synthesis & Catalysis 354 (14‐15), 2706-2712, 2012 | 33 | 2012 |
Chemoenzymatic Total Synthesis of (+)‐Galanthamine and (+)‐Narwedine from Phenethyl Acetate MAA Endoma‐Arias, T Hudlicky Chemistry–A European Journal 22 (41), 14540-14543, 2016 | 32 | 2016 |
Chemoenzymatic total synthesis of (+)-oxycodone from phenethyl acetate MAA Endoma-Arias, M Makarova, HED Paz, T Hudlicky Synthesis 51 (01), 225-232, 2019 | 25 | 2019 |
Chemoenzymatic and electrochemical oxidations in the synthesis of octahydroisoquinolines for conversion to morphine. Relative merits of radical vs. acid-catalyzed cyclizations MA Endoma, G Butora, CD Claeboe, T Hudlicky, KA Abboud Tetrahedron letters 38 (51), 8833-8836, 1997 | 25 | 1997 |
Conversion of Thebaine to Oripavine and Other Useful Intermediates for the Semisynthesis of Opiate‐Derived Agents: Synthesis of Hydromorphone B Murphy, I Šnajdr, A Machara, MAA Endoma‐Arias, TC Stamatatos, ... Advanced Synthesis & Catalysis 356 (11‐12), 2679-2687, 2014 | 24 | 2014 |
A short synthesis of nonracemic iodocyclohexene carboxylate fragment for kibdelone and congeners MAA Endoma-Arias, T Hudlicky Tetrahedron letters 52 (49), 6632-6634, 2011 | 24 | 2011 |
Nucleophilic substitution of protected β-bromoethyl cyclohexadiene-cis-diol as an alternative to direct microbial oxidation of β-functionalized phenethyl substrates M Ann A áEndoma Journal of the Chemical Society, Perkin Transactions 1, 2187-2192, 1996 | 23 | 1996 |
New chiral synthons from the microbial oxidation of bromonaphthalenes T Hudlicky, MAA Endoma, G Butora Tetrahedron: Asymmetry 7 (1), 61-68, 1996 | 23 | 1996 |
Toluene dioxygenase mediated oxidation of halogen-substituted benzoate esters V Semak, TA Metcalf, MAA Endoma-Arias, P Mach, T Hudlicky Organic & Biomolecular Chemistry 10 (22), 4407-4416, 2012 | 21 | 2012 |
Methods for one-pot N-demethylation/N-functionalization of morphine and tropane alkaloids T Hudlicky, RJ Carroll, H Leisch, A Machara, L Werner, MA Endoma-Arias US Patent 8,962,841, 2015 | 16 | 2015 |
Processing of o-Halobenzoates by Toluene Dioxygenase. The Role of the Alkoxy Functionality in the Regioselectivity of the Enzymatic Dihydroxylation Reaction J Froese, MAA Endoma-Arias, T Hudlicky Organic Process Research & Development 18 (6), 801-809, 2014 | 15 | 2014 |
Intramolecular N-Acyliminium Ion-Olefin Cyclization in the Synthesis of Optically Pure Isoquinoline Derivatives: Control of Stereochemistry and Application to Synthesis of … P Bottari, MAA Endoma, T Hudlický, I Ghiviriga, KA Abboud Collection of Czechoslovak chemical communications 64 (2), 203-216, 1999 | 13 | 1999 |
Synthesis of nororipavine and noroxymorphone via N-and O-demethylation of iron tricarbonyl complex of thebaine A Machara, MAA Endoma-Arias, I Císařova, DP Cox, T Hudlický Synthesis, 1803-1813, 2016 | 12 | 2016 |
Chemoenzymatic Total Synthesis of (+)-10-Keto-Oxycodone from Phenethyl Acetate MA Endoma-Arias, H Dela Paz, T Hudlicky Molecules 24 (19), 3477, 2019 | 11 | 2019 |