David Baez-Nieto
David Baez-Nieto
Senior Scientist at Neumora Therapeutics
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K+ Channels: Function‐Structural Overview
C González, D Baez‐Nieto, I Valencia, I Oyarzún, P Rojas, D Naranjo, ...
Comprehensive physiology 2 (3), 2087-2149, 2012
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels
HO Heyne, D Baez-Nieto, S Iqbal, DS Palmer, A Brunklaus, P May, ...
Science translational medicine 12 (556), eaay6848, 2020
Molecular determinants of phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P2) binding to transient receptor potential V1 (TRPV1) channels
H Poblete, I Oyarzún, P Olivero, J Comer, M Zuñiga, RV Sepulveda, ...
Journal of Biological Chemistry 290 (4), 2086-2098, 2015
Biological concepts in human sodium channel epilepsies and their relevance in clinical practice
A Brunklaus, J Du, F Steckler, II Ghanty, KM Johannesen, CD Fenger, ...
Epilepsia 61 (3), 387-399, 2020
Thermo-TRP channels: biophysics of polymodal receptors
D Baez-Nieto, JP Castillo, C Dragicevic, O Alvarez, R Latorre
Transient Receptor Potential Channels, 469-490, 2011
Gating of thermally activated channels
D Baez, N Raddatz, G Ferreira, C Gonzalez, R Latorre
Current topics in membranes 74, 51-87, 2014
Extracellular cysteine in connexins: role as redox sensors
MA Retamal, IE García, BI Pinto, A Pupo, D Báez, J Stehberg, R Del Rio, ...
Frontiers in physiology 7, 1, 2016
Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons
C Lu, X Shi, A Allen, D Baez-Nieto, A Nikish, NE Sanjana, JQ Pan
The FASEB Journal 33 (4), 5287, 2019
Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits
A Ghoshal, DS Uygun, L Yang, JM McNally, VG Lopez-Huerta, ...
Translational Psychiatry 10 (1), 29, 2020
Proton channel models: filling the gap between experimental data and the structural rationale
A Pupo, D Baez-Nieto, A Martínez, R Latorre, C González
Channels 8 (3), 180-192, 2014
Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort
D Baez-Nieto, A Allen, S Akers-Campbell, L Yang, N Budnik, A Pupo, ...
Brain 145 (5), 1839-1853, 2022
Could an allosteric gating model explain the role of TRPA1 in cold hypersensitivity?
M Salazar, H Moldenhauer, D Baez-Nieto
Journal of Neuroscience 31 (15), 5554-5556, 2011
Developing high-throughput assays to analyze and screen electrophysiological phenotypes
JQ Pan, D Baez-Nieto, A Allen, HR Wang, JR Cottrell
Phenotypic Screening: Methods and Protocols, 235-252, 2018
Voltage-gated proton (Hv1) channels, a singular voltage sensing domain
K Castillo, A Pupo, D Baez-Nieto, GF Contreras, FJ Morera, A Neely, ...
FEBS letters 589 (22), 3471-3478, 2015
Ion Channel drugs suppress cancer phenotype in NG108-15 and U87 cells: toward novel electroceuticals for glioblastoma
J Mathews, F Kuchling, D Baez-Nieto, M Diberardinis, JQ Pan, M Levin
Cancers 14 (6), 1499, 2022
Epi25 Collaborative
HO Heyne, D Baez-Nieto, S Iqbal, DS Palmer, A Brunklaus, P May
Johannesen KM, Lauxmann S, Lemke JR, Møller RS, Pérez-Palma E, Scholl UI …, 2020
Voltage-Dependence in Thermo-Voltage Sensitive Channel TRPV1. A Delocalized Voltage Sensor?
D Baez-Nieto, O Alvarez, S Brauchi, C Gonzalez, R Latorre
Biophysical Journal 104 (2), 456a, 2013
Properties of the voltage-gated proton channel gating currents
EM Carmona, D Baez-Nieto, A Pupo, K Castillo, O Alvarez, A Neely, ...
Biophysical Journal 114 (3), 546a, 2018
Functional analysis of human GRIN2A mutations associated with schizophrenia and neurodevelopmental disorders reveals distinct pathological mechanism
N Shepard, D Baez-Nieto, S Iqbal, AJ Campbell, JQ Pan, M Sheng, ...
bioRxiv, 2023.08. 02.551645, 2023
Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators
YL Zhang, SP Moran, A Allen, D Baez-Nieto, Q Xu, LA Wang, ...
ACS Pharmacology & Translational Science 5 (3), 156-168, 2022
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20