| Battles with iron: manganese in oxidative stress protection JD Aguirre, VC Culotta Journal of Biological Chemistry 287 (17), 13541-13548, 2012 | 330 | 2012 |
| Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis A Kumar, JD Aguirre, TEC Condos, RJ Martinez‐Torres, VK Chaugule, ... The EMBO journal 34 (20), 2506-2521, 2015 | 181 | 2015 |
| A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease DE Spratt, R Julio Martinez-Torres, YJ Noh, P Mercier, N Manczyk, ... Nature communications 4 (1), 1983, 2013 | 138 | 2013 |
| Dirhodium (II, II) complexes: molecular characteristics that affect in vitro activity AM Angeles-Boza, HT Chifotides, JD Aguirre, A Chouai, PKL Fu, ... Journal of medicinal chemistry 49 (23), 6841-6847, 2006 | 137 | 2006 |
| Live cell cytotoxicity studies: documentation of the interactions of antitumor active dirhodium compounds with nuclear DNA JD Aguirre, AM Angeles-Boza, A Chouai, JP Pellois, C Turro, KR Dunbar Journal of the American Chemical Society 131 (32), 11353-11360, 2009 | 110 | 2009 |
| Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation JD Aguirre, KM Dunkerley, P Mercier, GS Shaw Proceedings of the National Academy of Sciences 114 (2), 298-303, 2017 | 98 | 2017 |
| Photophysical properties, DNA photocleavage, and photocytotoxicity of a series of dppn dirhodium (II, II) complexes LE Joyce, JD Aguirre, AM Angeles-Boza, A Chouai, PKL Fu, KR Dunbar, ... Inorganic chemistry 49 (12), 5371-5376, 2010 | 97 | 2010 |
| A manganese-rich environment supports superoxide dismutase activity in a Lyme disease pathogen, Borrelia burgdorferi JD Aguirre, HM Clark, M McIlvin, C Vazquez, SL Palmere, DJ Grab, ... Journal of Biological Chemistry 288 (12), 8468-8478, 2013 | 87 | 2013 |
| Effect of axial coordination on the electronic structure and biological activity of dirhodium (II, II) complexes JD Aguirre, DA Lutterman, AM Angeles-Boza, KR Dunbar, C Turro Inorganic Chemistry 46 (18), 7494-7502, 2007 | 80 | 2007 |
| Anticancer activity of heteroleptic diimine complexes of dirhodium: A study of intercalating properties, hydrophobicity and in cellulo activity JD Aguirre, AM Angeles-Boza, A Chouai, C Turro, JP Pellois, KR Dunbar Dalton Transactions, 10806-10812, 2009 | 53 | 2009 |
| Structural basis of BRCC36 function in DNA repair and immune regulation J Rabl, RD Bunker, AD Schenk, S Cavadini, ME Gill, W Abdulrahman, ... Molecular cell 75 (3), 483-497. e9, 2019 | 51 | 2019 |
| Redox-regulated Inhibition of T7 RNA polymerase via establishment of disulfide linkages by substituted Dppz dirhodium (II, II) complexes JD Aguirre, HT Chifotides, AM Angeles-Boza, A Chouai, C Turro, ... Inorganic chemistry 48 (10), 4435-4444, 2009 | 41 | 2009 |
| Synergistic recruitment of UbcH7~ Ub and phosphorylated Ubl domain triggers parkin activation TEC Condos, KM Dunkerley, EA Freeman, KR Barber, JD Aguirre, ... The EMBO journal 37 (23), e100014, 2018 | 38 | 2018 |
| Generation of phospho‐ubiquitin variants by orthogonal translation reveals codon skipping S George, JD Aguirre, DE Spratt, Y Bi, M Jeffery, GS Shaw, P O'Donoghue FEBS letters 590 (10), 1530-1542, 2016 | 36 | 2016 |
| Impact of altered phosphorylation on loss of function of juvenile Parkinsonism–associated genetic variants of the E3 ligase parkin JD Aguirre, KM Dunkerley, R Lam, M Rusal, GS Shaw Journal of Biological Chemistry 293 (17), 6337-6348, 2018 | 30 | 2018 |
| Teaching Chemistry in the Time of COVID-19: Memories and the Classroom JD Aguirre, F Selampinar Journal of Chemical Education 97 (9), 2909-2912, 2020 | 25 | 2020 |
| UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability JM Tsai, JD Aguirre, YD Li, J Brown, V Focht, L Kater, G Kempf, ... Molecular Cell 83 (15), 2753-2767. e10, 2023 | 14 | 2023 |
| Orphan quality control shapes network dynamics and gene expression KG Mark, SDD Kolla, JD Aguirre, DM Garshott, S Schmitt, DL Haakonsen, ... Cell 186 (16), 3460-3475. e23, 2023 | 13 | 2023 |
| FANally… A Structure Emerges of the Fanconi Anemia Core Complex JD Aguirre, NH Thomä Trends in biochemical sciences 45 (4), 275-276, 2020 | 1 | 2020 |
| UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability JM Tsai, JD Aguirre, J Brown, V Focht, YD Li, G Kempf, L Kater, P Galli, ... Blood 140 (Supplement 1), 2968-2969, 2022 | | 2022 |
Alfredo M. Angeles-BozaAssociate Professor of Chemistry, University of ConnecticutVerified email at uconn.edu
