| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10714 | 2021 |
| Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization J Van Loosdregt, Y Vercoulen, T Guichelaar, YYJ Gent, JM Beekman, ... Blood, The Journal of the American Society of Hematology 115 (5), 965-974, 2010 | 413 | 2010 |
| Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor DMW Zaiss, J Van Loosdregt, A Gorlani, CPJ Bekker, A Gröne, M Sibilia, ... Immunity 38 (2), 275-284, 2013 | 401 | 2013 |
| Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity J van Loosdregt, V Fleskens, J Fu, AB Brenkman, CPJ Bekker, ... Immunity 39 (2), 259-271, 2013 | 324 | 2013 |
| Canonical Wnt signaling negatively modulates regulatory T cell function J Van Loosdregt, V Fleskens, MM Tiemessen, M Mokry, R van Boxtel, ... Immunity 39 (2), 298-310, 2013 | 222 | 2013 |
| Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells EJ Wehrens, G Mijnheer, CL Duurland, M Klein, J Meerding, ... Blood, The Journal of the American Society of Hematology 118 (13), 3538-3548, 2011 | 186 | 2011 |
| Proinflammatory T cells and IL-17 stimulate osteoblast differentiation M Croes, FC Öner, D van Neerven, E Sabir, MC Kruyt, TJ Blokhuis, ... Bone 84, 262-270, 2016 | 177 | 2016 |
| The chemokine and chemokine receptor profile of infiltrating cells in the wall of arteries with cardiac allograft vasculopathy is indicative of a memory T–helper 1 response J van Loosdregt, MFM van Oosterhout, AH Bruggink, DF van Wichen, ... Circulation 114 (15), 1599-1607, 2006 | 143 | 2006 |
| Treatment to target using recombinant interleukin‐1 receptor antagonist as first‐line monotherapy in new‐onset systemic juvenile idiopathic arthritis: results from a five‐year … NM Ter Haar, EHP van Dijkhuizen, JF Swart, A van Royen‐Kerkhof, ... Arthritis & Rheumatology 71 (7), 1163-1173, 2019 | 139 | 2019 |
| Rapid temporal control of Foxp3 protein degradation by sirtuin-1 J van Loosdregt, D Brunen, V Fleskens, CEGM Pals, EWF Lam, PJ Coffer PloS one 6 (4), e19047, 2011 | 130 | 2011 |
| Ex vivo–expanded but not in vitro–induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory … M Rossetti, R Spreafico, S Saidin, C Chua, M Moshref, JY Leong, YK Tan, ... The Journal of Immunology 194 (1), 113-124, 2015 | 112 | 2015 |
| Post-translational modification networks regulating FOXP3 function J van Loosdregt, PJ Coffer Trends in immunology 35 (8), 368-378, 2014 | 108 | 2014 |
| Inhibition of super-enhancer activity in autoinflammatory site-derived T cells reduces disease-associated gene expression JGC Peeters, SJ Vervoort, SC Tan, G Mijnheer, S de Roock, SJ Vastert, ... Cell reports 12 (12), 1986-1996, 2015 | 104 | 2015 |
| Increased autophagy in CD4+ T cells of rheumatoid arthritis patients results in T‐cell hyperactivation and apoptosis resistance J van Loosdregt, M Rossetti, R Spreafico, M Moshref, M Olmer, ... European journal of immunology 46 (12), 2862-2870, 2016 | 92 | 2016 |
| Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60 Y Gao, A Koppen, M Rakhshandehroo, I Tasdelen, SF Van De Graaf, ... Nature communications 4 (1), 2656, 2013 | 92 | 2013 |
| A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment R Spreafico, M Rossetti, J van Loosdregt, CA Wallace, M Massa, ... Annals of the rheumatic diseases 75 (2), 459-465, 2016 | 79 | 2016 |
| Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cells J van Loosdregt, R Spreafico, M Rossetti, BJ Prakken, M Lotz, S Albani Journal of Allergy and Clinical Immunology 131 (5), 1443-1446. e1, 2013 | 59 | 2013 |
| Syntenin-mediated regulation of Sox4 proteasomal degradation modulates transcriptional output JM Beekman, SJ Vervoort, F Dekkers, ME van Vessem, S Vendelbosch, ... Oncogene 31 (21), 2668-2679, 2012 | 53 | 2012 |
| Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation G Mijnheer, L Lutter, M Mokry, M van der Wal, R Scholman, V Fleskens, ... Nature communications 12 (1), 2710, 2021 | 52 | 2021 |
| Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation M Bartels, AM Govers, V Fleskens, AR Lourenço, CE Pals, SJ Vervoort, ... Blood, The Journal of the American Society of Hematology 125 (11), 1782-1792, 2015 | 52 | 2015 |
