Seguir
BRIAN WALKER
BRIAN WALKER
Professor of Biomedicinal Chemistry, Queen's University Belfast
Dirección de correo verificada de qub.ac.uk
Título
Citado por
Citado por
Año
Proteasome inhibitors in cancer therapy
LJ Crawford, B Walker, AE Irvine
Journal of cell communication and signaling 5, 101-110, 2011
4142011
Neutrophil elastase activity is associated with exacerbations and lung function decline in bronchiectasis
JD Chalmers, KL Moffitt, G Suarez-Cuartin, O Sibila, S Finch, E Furrie, ...
American journal of respiratory and critical care medicine 195 (10), 1384-1393, 2017
2992017
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells
S Wilson, B Greer, J Hooper, A Zijlstra, B Walker, J Quigley, S Hawthorne
Biochemical Journal 388 (3), 967-972, 2005
2282005
Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132
LJA Crawford, B Walker, H Ovaa, D Chauhan, KC Anderson, TCM Morris, ...
Cancer research 66 (12), 6379-6386, 2006
1892006
Strategies for the inhibition of serine proteases
B Walker, JF Lynas
Cellular and Molecular Life Sciences CMLS 58, 596-624, 2001
1532001
Organophosphorus Chemistry: Volume 21
BJ Walker, JB Hobbs
Royal Society of chemistry, 2007
1322007
The clinical significance of cathepsin S expression in human astrocytomas
T Flannery, D Gibson, M Mirakhur, S McQuaid, C Greenan, A Trimble, ...
The American journal of pathology 163 (1), 175-182, 2003
1302003
Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection
GRA Cathcart, D Quinn, B Greer, P Harriott, JF Lynas, BF Gilmore, ...
Antimicrobial agents and chemotherapy 55 (6), 2670-2678, 2011
1262011
Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo
C Cicala, A Pinto, M Bucci, R Sorrentino, B Walker, P Harriot, A Cruchley, ...
Circulation 99 (19), 2590-2597, 1999
1191999
The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases
P Rauber, H Angliker, B Walker, E Shaw
Biochemical Journal 239 (3), 633-640, 1986
1191986
Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis
RE Burden, JA Gormley, TJ Jaquin, DM Small, DJ Quinn, SM Hegarty, ...
Clinical Cancer Research 15 (19), 6042-6051, 2009
1132009
Antimicrobial/cytolytic peptides from the venom of the North African scorpion, Androctonus amoreuxi: biochemical and functional characterization of natural peptides and a …
A Almaaytah, M Zhou, L Wang, T Chen, B Walker, C Shaw
Peptides 35 (2), 291-299, 2012
1092012
A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis
G Stephens, N O'Luanaigh, D Reilly, P Harriott, B Walker, D Fitzgerald, ...
Journal of Biological Chemistry 273 (32), 20317-20322, 1998
1081998
Cathepsin S from both tumor and tumor‐associated cells promote cancer growth and neovascularization
DM Small, RE Burden, J Jaworski, SM Hegarty, S Spence, JF Burrows, ...
International journal of cancer 133 (9), 2102-2112, 2013
1062013
Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation
NG Arizmendi, M Abel, K Mihara, C Davidson, D Polley, A Nadeem, ...
The Journal of Immunology 186 (5), 3164-3172, 2011
1042011
A highly convenient route to optically pure α-aminophosphonic acids
R Hamilton, B Walker, BJ Walker
Tetrahedron letters 36 (25), 4451-4454, 1995
991995
Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels
CJ Scott, A McDOWELL, SL Martin, JF Lynas, K Vandenbroeck, B Walker
Biochemical Journal 366 (3), 953-958, 2002
982002
Importance of the P4′ residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop
J Sun, JC Whisstock, P Harriott, B Walker, A Novak, PE Thompson, ...
Journal of Biological Chemistry 276 (18), 15177-15184, 2001
962001
Cathepsin S expression: an independent prognostic factor in glioblastoma tumours—a pilot study
T Flannery, S McQuaid, C McGoohan, RS McConnell, G McGregor, ...
International journal of cancer 119 (4), 854-860, 2006
942006
Identification of potential activators of proteinase‐activated receptor‐2 1
MT Fox, P Harriott, B Walker, SR Stone
FEBS letters 417 (3), 267-269, 1997
901997
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20