Mosquito hemocytes preferentially aggregate and phagocytose pathogens in the periostial regions of the heart that experience the most hemolymph flow LT Sigle, JF Hillyer Developmental & Comparative Immunology 55, 90-101, 2016 | 69 | 2016 |
Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness SA Ford, SL Allen, JR Ohm, LT Sigle, A Sebastian, I Albert, SF Chenoweth, ... Nature Microbiology 4 (11), 1832-1839, 2019 | 55 | 2019 |
Mosquito hemocytes associate with circulatory structures that support intracardiac retrograde hemolymph flow LT Sigle, JF Hillyer Frontiers in physiology 9, 408208, 2018 | 25 | 2018 |
Expanding the canon: Non-classical mosquito genes at the interface of arboviral infection LT Sigle, EA McGraw Insect biochemistry and molecular biology 109, 72-80, 2019 | 23 | 2019 |
Eater and draper are involved in the periostial haemocyte immune response in the mosquito Anopheles gambiae LT Sigle, JF Hillyer Insect molecular biology 27 (4), 429-438, 2018 | 19 | 2018 |
Nitric oxide produced by periostial hemocytes modulates the bacterial infection-induced reduction of the mosquito heart rate TY Estévez-Lao, LT Sigle, SN Gomez, JF Hillyer Journal of Experimental Biology 223 (15), jeb225821, 2020 | 16 | 2020 |
Structural and functional characterization of the contractile aorta and associated hemocytes of the mosquito Anopheles gambiae LT Sigle, JF Hillyer Journal of Experimental Biology 221 (12), jeb181107, 2018 | 13 | 2018 |
Artificial Selection Finds New Hypotheses for the Mechanism of Wolbachia-Mediated Dengue Blocking in Mosquitoes SA Ford, I Albert, SL Allen, SF Chenoweth, M Jones, C Koh, A Sebastian, ... Frontiers in Microbiology 11, 1456, 2020 | 11 | 2020 |
Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi LT Sigle, M Ramalho-Ortigão Memórias do Instituto Oswaldo Cruz 108, 671-678, 2013 | 10 | 2013 |
Assessing Aedes aegypti candidate genes during viral infection and Wolbachia‐mediated pathogen blocking LT Sigle, M Jones, M Novelo, SA Ford, N Urakova, K Lymperopoulos, ... Insect molecular biology 31 (3), 356-368, 2022 | 8 | 2022 |
The immune deficiency and c-Jun N-terminal kinase pathways drive the functional integration of the immune and circulatory systems of mosquitoes Y Yan, LT Sigle, DC Rinker, TY Estévez-Lao, JA Capra, JF Hillyer Open Biology 12 (9), 220111, 2022 | 7 | 2022 |
An alternative pathway to eusociality: Exploring the molecular and functional basis of fortress defense SP Lawson, LT Sigle, AL Lind, AW Legan, JN Mezzanotte, HW Honegger, ... Evolution 71 (8), 1986-1998, 2017 | 7 | 2017 |
Selection on Aedes aegypti alters Wolbachia-mediated dengue virus blocking and fitness. Nat Microbiol 4: 1832–1839 SA Ford, SL Allen, JR Ohm, LT Sigle, A Sebastian, I Albert, SF Chenoweth, ... | 6 | 2019 |
Dengue and chikungunya virus loads in the mosquito Aedes aegypti are determined by distinct genetic architectures M Novelo, HLC Dutra, HC Metz, MJ Jones, LT Sigle, FD Frentiu, SL Allen, ... PLoS pathogens 19 (4), e1011307, 2023 | 5 | 2023 |
Alpha‐mannosidase‐2 modulates arbovirus infection in a pathogen‐ and Wolbachia‐specific manner in Aedes aegypti mosquitoes N Urakova, RE Joseph, A Huntsinger, VM Macias, MJ Jones, LT Sigle, ... Insect Molecular Biology, 2024 | 1 | 2024 |
Uncovering the expression profile of periostial hemocytes in the mosquito Anopheles gambiae Y Yan, LT Sigle, DC Rinker, TY Estevez-Lao, JA Capra, JF Hillyer Entomology 2019, 2019 | | 2019 |
Physiological and Molecular Characterization of the Interactions between the Cellular Immune Response and the Circulatory System of the Mosquito Anopheles gambiae LT Sigle | | 2018 |
A comprehensive transcriptome profile of the heart of Anopheles gambiae DC Rinker, LT Sigle, JA Capra, JF Hillyer Entomology 2017, 2017 | | 2017 |
Immune gene expression varies across different mosquito tissues containing either circulating, sessile, or periostial hemocytes LT Sigle, TY Estevez-Lao, DC Rinker, JA Capra, JF Hillyer Entomology 2017, 2017 | | 2017 |
Circulatory and immune system interactions in a mosquito LT Sigle, JF Hillyer 2016 International Congress of Entomology, 2016 | | 2016 |