| Systems analysis of effector caspase activation and its control by X‐linked inhibitor of apoptosis protein M Rehm, HJ Huber, H Dussmann, JHM Prehn The EMBO journal 25 (18), 4338-4349, 2006 | 250 | 2006 |
| The balance of interleukin (IL)-6, IL-6· soluble IL-6 receptor (sIL-6R), and IL-6· sIL-6R· sgp130 complexes allows simultaneous classic and trans-signaling P Baran, S Hansen, GH Waetzig, M Akbarzadeh, L Lamertz, HJ Huber, ... Journal of Biological Chemistry 293 (18), 6762-6775, 2018 | 192 | 2018 |
| Dynamics of outer mitochondrial membrane permeabilization during apoptosis M Rehm, HJ Huber, CT Hellwig, S Anguissola, H Dussmann, JHM Prehn Cell Death & Differentiation 16 (4), 613-623, 2009 | 151 | 2009 |
| Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance MW Ward, HJ Huber, P Weisová, H Düssmann, DG Nicholls, JHM Prehn Journal of Neuroscience 27 (31), 8238-8249, 2007 | 135 | 2007 |
| Response to IL-6 trans-and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling H Reeh, N Rudolph, U Billing, H Christen, S Streif, E Bullinger, ... Cell Communication and Signaling 17, 1-21, 2019 | 120 | 2019 |
| Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation H Düssmann, M Rehm, CG Concannon, S Anguissola, M Würstle, ... Cell Death & Differentiation 17 (2), 278-290, 2010 | 113 | 2010 |
| Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy AU Lindner, CG Concannon, GJ Boukes, MD Cannon, F Llambi, D Ryan, ... Cancer research 73 (2), 519-528, 2013 | 106 | 2013 |
| Exosomes: emerging roles in communication between blood cells and vascular tissues during atherosclerosis HJ Huber, P Holvoet Current opinion in lipidology 26 (5), 412-419, 2015 | 99 | 2015 |
| Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate D Davila, NMC Connolly, H Bonner, P Weisova, H Dussmann, ... Cell Death & Differentiation 19 (10), 1677-1688, 2012 | 80 | 2012 |
| Predicting pKa Values of Substituted Phenols from Atomic Charges: Comparison of Different Quantum Mechanical Methods and Charge Distribution Schemes R Svobodová Vařeková, S Geidl, CM Ionescu, O Skrehota, M Kudera, ... Journal of chemical information and modeling 51 (8), 1795-1806, 2011 | 72 | 2011 |
| Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation NMC Connolly, H Düssmann, U Anilkumar, HJ Huber, JHM Prehn Journal of Neuroscience 34 (31), 10192-10205, 2014 | 67 | 2014 |
| Activation of executioner caspases is a predictor of progression-free survival in glioblastoma patients: a systems medicine approach ÁC Murphy, B Weyhenmeyer, J Schmid, SM Kilbride, M Rehm, HJ Huber, ... Cell death & disease 4 (5), e629-e629, 2013 | 62 | 2013 |
| Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome‐c release HJ Huber, H Dussmann, SM Kilbride, M Rehm, JHM Prehn Molecular systems biology 7 (1), 470, 2011 | 57 | 2011 |
| Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy S Hector, M Rehm, J Schmid, J Kehoe, N McCawley, P Dicker, F Murray, ... Gut 61 (5), 725-733, 2012 | 56 | 2012 |
| Doxorubicin-induced chronic dilated cardiomyopathy—the apoptosis hypothesis revisited C Kankeu, K Clarke, E Passante, HJ Huber Journal of Molecular Medicine 95 (3), 239-248, 2017 | 49 | 2017 |
| Proteasome inhibition can impair caspase-8 activation upon submaximal stimulation of apoptotic tumor necrosis factor-related apoptosis inducing ligand (TRAIL) signaling MA Laussmann, E Passante, CT Hellwig, B Tomiczek, L Flanagan, ... Journal of Biological Chemistry 287 (18), 14402-14411, 2012 | 46 | 2012 |
| Mathematical modelling of the mitochondrial apoptosis pathway HJ Huber, H Duessmann, J Wenus, SM Kilbride, JHM Prehn Biochimica et biophysica acta (BBA)-molecular cell research 1813 (4), 608-615, 2011 | 44 | 2011 |
| Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein CL O'Connor, S Anguissola, HJ Huber, H Dussmann, JHM Prehn, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (10), 1903-1913, 2008 | 37 | 2008 |
| Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization J Schmid, H Dussmann, GJ Boukes, L Flanagan, AU Lindner, ... Journal of Biological chemistry 287 (49), 41546-41559, 2012 | 36 | 2012 |
| APOPTO-CELL—a simulation tool and interactive database for analyzing cellular susceptibility to apoptosis HJ Huber, M Rehm, M Plchut, H Düssmann, JHM Prehn Bioinformatics 23 (5), 648-650, 2007 | 36 | 2007 |
Prof Dr Markus Morrison (Rehm)Director, Institute of Cell Biology and Immunology, University of Stuttgart, GermanyCorreu electrònic verificat a izi.uni-stuttgart.de
