| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5363 | 2018 |
| Necroptosis and its role in inflammation M Pasparakis, P Vandenabeele Nature 517 (7534), 311-320, 2015 | 1890 | 2015 |
| Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies D Kontoyiannis, M Pasparakis, TT Pizarro, F Cominelli, G Kollias Immunity 10 (3), 387-398, 1999 | 1662 | 1999 |
| Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury Y Imai, K Kuba, GG Neely, R Yaghubian-Malhami, T Perkmann, ... Cell 133 (2), 235-249, 2008 | 1549 | 2008 |
| Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell … M Pasparakis, L Alexopoulou, V Episkopou, G Kollias The Journal of experimental medicine 184 (4), 1397-1411, 1996 | 1426 | 1996 |
| Epithelial NEMO links innate immunity to chronic intestinal inflammation A Nenci, C Becker, A Wullaert, R Gareus, G Van Loo, S Danese, M Huth, ... Nature 446 (7135), 557-561, 2007 | 1204 | 2007 |
| Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis RJ Moore, DM Owens, G Stamp, C Arnott, F Burke, N East, H Holdsworth, ... Nature medicine 5 (7), 828-831, 1999 | 1041 | 1999 |
| Mechanisms regulating skin immunity and inflammation M Pasparakis, I Haase, FO Nestle Nature reviews immunology 14 (5), 289-301, 2014 | 980 | 2014 |
| Synchronized renal tubular cell death involves ferroptosis A Linkermann, R Skouta, N Himmerkus, SR Mulay, C Dewitz, F De Zen, ... Proceedings of the National Academy of Sciences 111 (47), 16836-16841, 2014 | 942 | 2014 |
| SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis F Ikeda, YL Deribe, SS Skånland, B Stieglitz, C Grabbe, M Franz-Wachtel, ... Nature 471 (7340), 637-641, 2011 | 784 | 2011 |
| Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma T Luedde, N Beraza, V Kotsikoris, G van Loo, A Nenci, R De Vos, ... Cancer cell 11 (2), 119-132, 2007 | 676 | 2007 |
| Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis M Fritsch, SD Günther, R Schwarzer, MC Albert, F Schorn, ... Nature 575 (7784), 683-687, 2019 | 669 | 2019 |
| FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation PS Welz, A Wullaert, K Vlantis, V Kondylis, V Fernández-Majada, ... Nature 477 (7364), 330-334, 2011 | 665 | 2011 |
| Regulation of tissue homeostasis by NF-κB signalling: implications for inflammatory diseases M Pasparakis Nature Reviews Immunology 9 (11), 778-788, 2009 | 645 | 2009 |
| Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ... Nature 468 (7320), 98-102, 2010 | 632 | 2010 |
| NEMO/IKKγ-deficient mice model incontinentia pigmenti M Schmidt-Supprian, W Bloch, G Courtois, K Addicks, A Israël, ... Molecular cell 5 (6), 981-992, 2000 | 565 | 2000 |
| TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2 M Pasparakis, G Courtois, M Hafner, M Schmidt-Supprian, A Nenci, ... Nature 417 (6891), 861-866, 2002 | 556 | 2002 |
| NF-κB in the regulation of epithelial homeostasis and inflammation A Wullaert, MC Bonnet, M Pasparakis Cell research 21 (1), 146-158, 2011 | 550 | 2011 |
| CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair S Willenborg, T Lucas, G Van Loo, JA Knipper, T Krieg, I Haase, ... Blood, The Journal of the American Society of Hematology 120 (3), 613-625, 2012 | 538 | 2012 |
| RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS Y Ito, D Ofengeim, A Najafov, S Das, S Saberi, Y Li, J Hitomi, H Zhu, ... Science 353 (6299), 603-608, 2016 | 525 | 2016 |
