Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice L Sevenich, U Schurigt, K Sachse, M Gajda, F Werner, S Müller, ... Proceedings of the National Academy of Sciences 107 (6), 2497-2502, 2010 | 186 | 2010 |
Relative contribution of matrix metalloprotease and cysteine protease activities to cytokine-stimulated articular cartilage degradation BC Sondergaard, K Henriksen, H Wulf, S Oestergaard, U Schurigt, ... Osteoarthritis and cartilage 14 (8), 738-748, 2006 | 150 | 2006 |
CXCR5‐and CCR7‐dependent lymphoid neogenesis in a murine model of chronic antigen‐induced arthritis AM Wengner, UE Höpken, PK Petrow, S Hartmann, U Schurigt, R Bräuer, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2007 | 130 | 2007 |
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice O Vasiljeva, M Korovin, M Gajda, H Brodoefel, L Bojic, A Krüger, ... Oncogene 27 (30), 4191-4199, 2008 | 127 | 2008 |
Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice L Sevenich, F Werner, M Gajda, U Schurigt, C Sieber, S Müller, M Follo, ... Oncogene 30 (1), 54-64, 2011 | 89 | 2011 |
Autophagic digestion of Leishmania major by host macrophages is associated with differential expression of BNIP3, CTSE, and the miRNAs miR-101c, miR-129 … B Frank, A Marcu, AL de Oliveira Almeida Petersen, H Weber, C Stigloher, ... Parasites & vectors 8, 1-31, 2015 | 88 | 2015 |
Valeriana wallichii root extracts and fractions with activity against Leishmania spp S Ghosh, S Debnath, S Hazra, A Hartung, K Thomale, M Schultheis, ... Parasitology research 108, 861-871, 2011 | 80 | 2011 |
The expression and localization of somatostatin receptors in dorsal root ganglion neurons of normal and monoarthritic rats KJ Bär, U Schurigt, A Scholze, GS Von Banchet, N Stopfel, R Bräuer, ... Neuroscience 127 (1), 197-206, 2004 | 69 | 2004 |
Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis U Schurigt, N Stopfel, M Hückel, C Pfirschke, B Wiederanders, R Bräuer Arthritis Res Ther 7, 1-15, 2004 | 60 | 2004 |
Morphology of bony tissues and implants uncovered by high-resolution tomographic imaging B Müller, R Bernhardt, T Weitkamp, F Beckmann, R Bräuer, U Schurigt, ... International Journal of Materials Research 98 (7), 613-621, 2007 | 53 | 2007 |
Glycosome turnover in Leishmania major is mediated by autophagy B Cull, JL Prado Godinho, JC Fernandes Rodrigues, B Frank, U Schurigt, ... Autophagy 10 (12), 2143-2157, 2014 | 51 | 2014 |
Aziridine-2,3-Dicarboxylate-Based Cysteine Cathepsin Inhibitors Induce Cell Death in Leishmania major Associated with Accumulation of Debris in Autophagy … U Schurigt, C Schad, C Glowa, U Baum, K Thomale, JK Schnitzer, ... Antimicrobial agents and chemotherapy 54 (12), 5028-5041, 2010 | 51 | 2010 |
A novel Leishmania major amastigote assay in 96-well format for rapid drug screening and its use for discovery and evaluation of a new class of leishmanicidal quinolinium salts G Bringmann, K Thomale, S Bischof, C Schneider, M Schultheis, ... Antimicrobial agents and chemotherapy 57 (7), 3003-3011, 2013 | 49 | 2013 |
Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model U Schurigt, L Sevenich, C Vannier, M Gajda, A Schwinde, F Werner, ... Walter de Gruyter 389 (8), 1067-1074, 2008 | 49 | 2008 |
Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1) M Hückel, U Schurigt, AH Wagner, R Stöckigt, PK Petrow, K Thoss, ... Arthritis research & therapy 8, 1-13, 2005 | 46 | 2005 |
Antileishmanial lead structures from nature: Analysis of structure-activity relationships of a compound library derived from caffeic acid bornyl ester J Glaser, M Schultheis, S Hazra, B Hazra, H Moll, U Schurigt, U Holzgrabe Molecules 19 (2), 1394-1410, 2014 | 43 | 2014 |
Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor–transgenic mice U Schurigt, KM Hummel, PK Petrow, M Gajda, R Stöckigt, P Middel, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 39 | 2008 |
Anti-schistosomal activity of cinnamic acid esters: eugenyl and thymyl cinnamate induce cytoplasmic vacuoles and death in schistosomula of Schistosoma mansoni J Glaser, U Schurigt, BM Suzuki, CR Caffrey, U Holzgrabe Molecules 20 (6), 10873-10883, 2015 | 36 | 2015 |
Inhibitory effect of phenothiazine-and phenoxazine-derived chloroacetamides on Leishmania major growth and Trypanosoma brucei trypanothione reductase A Marcu, U Schurigt, K Müller, H Moll, RL Krauth-Siegel, H Prinz European Journal of Medicinal Chemistry 108, 436-443, 2016 | 31 | 2016 |
Decreased arthritis severity in cathepsin L-deficient mice is attributed to an impaired T helper cell compartment U Schurigt, R Eilenstein, M Gajda, C Leipner, L Sevenich, T Reinheckel, ... Inflammation Research 61, 1021-1029, 2012 | 30 | 2012 |