Keith L. Ligon
Keith L. Ligon
Associate Professor, Harvard Medical School
Dirección de correo verificada de dfci.harvard.edu - Página principal
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Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
36102015
Malignant astrocytic glioma: genetics, biology, and paths to treatment
FB Furnari, T Fenton, RM Bachoo, A Mukasa, JM Stommel, A Stegh, ...
Genes & development 21 (21), 2683-2710, 2007
23702007
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
JM Stommel, AC Kimmelman, H Ying, R Nabioullin, AH Ponugoti, ...
Science 318 (5848), 287-290, 2007
9822007
p16 INK4a induces an age-dependent decline in islet regenerative potential
J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ...
Nature 443 (7110), 453-457, 2006
9242006
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
RM Bachoo, EA Maher, KL Ligon, NE Sharpless, SS Chan, MJ You, ...
Cancer cell 1 (3), 269-277, 2002
7522002
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Nature 455 (7216), 1129-1133, 2008
7012008
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
P Koivunen, S Lee, CG Duncan, G Lopez, G Lu, S Ramkissoon, ...
Nature 483 (7390), 484-488, 2012
6252012
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of Clinical Oncology 29 (11), 1424, 2011
6132011
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
5602013
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma
U Schüller, VM Heine, J Mao, AT Kho, AK Dillon, YG Han, E Huillard, ...
Cancer cell 14 (2), 123-134, 2008
5482008
Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets
PK Brastianos, SL Carter, S Santagata, DP Cahill, A Taylor-Weiner, ...
Cancer discovery 5 (11), 1164-1177, 2015
5122015
Emerging insights into the molecular and cellular basis of glioblastoma
GP Dunn, ML Rinne, J Wykosky, G Genovese, SN Quayle, IF Dunn, ...
Genes & development 26 (8), 756-784, 2012
5082012
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma
KL Ligon, E Huillard, S Mehta, S Kesari, H Liu, JA Alberta, RM Bachoo, ...
Neuron 53 (4), 503-517, 2007
4682007
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations
PK Brastianos, PM Horowitz, S Santagata, RT Jones, A McKenna, G Getz, ...
Nature genetics 45 (3), 285-289, 2013
4252013
Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis.
JM Miano, P Cserjesi, KL Ligon, M Periasamy, EN Olson
Circulation research 75 (5), 803-812, 1994
4231994
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS Genet 6 (2), e1000841, 2010
3932010
Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis
P Cserjesi, D Brown, KL Ligon, GE Lyons, NG Copeland, DJ Gilbert, ...
Development 121 (4), 1099-1110, 1995
3931995
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas
KL Ligon, JA Alberta, AT Kho, J Weiss, MR Kwaan, CL Nutt, DN Louis, ...
Journal of neuropathology and experimental neurology 63 (5), 499-509, 2004
3782004
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
J Paik, Z Ding, R Narurkar, S Ramkissoon, F Muller, WS Kamoun, ...
Cell stem cell 5 (5), 540-553, 2009
3752009
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination
B Emery, D Agalliu, JD Cahoy, TA Watkins, JC Dugas, SB Mulinyawe, ...
Cell 138 (1), 172-185, 2009
3702009
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20