Sustainability challenges in peptide synthesis and purification: from R&D to production A Isidro-Llobet, MN Kenworthy, S Mukherjee, ME Kopach, K Wegner, ... The Journal of organic chemistry 84 (8), 4615-4628, 2019 | 315 | 2019 |
Two flavoenzymes catalyze the post-translational generation of 5-chlorotryptophan and 2-aminovinyl-cysteine during NAI-107 biosynthesis MA Ortega, DP Cogan, S Mukherjee, N Garg, B Li, GN Thibodeaux, ... ACS chemical biology 12 (2), 548-557, 2017 | 83 | 2017 |
Mechanistic studies on the substrate-tolerant lanthipeptide synthetase ProcM S Mukherjee, WA Van Der Donk Journal of the American Chemical Society 136 (29), 10450-10459, 2014 | 71 | 2014 |
Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster J Gao, KS Ju, X Yu, JE Velásquez, S Mukherjee, J Lee, C Zhao, BS Evans, ... Angewandte Chemie 126 (5), 1358-1361, 2014 | 56 | 2014 |
Product formation by the promiscuous lanthipeptide synthetase ProcM is under kinetic control Y Yu, S Mukherjee, WA Van Der Donk Journal of the American Chemical Society 137 (15), 5140-5148, 2015 | 49 | 2015 |
Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway DJ Bougioukou, S Mukherjee, WA Van Der Donk Proceedings of the National Academy of Sciences 110 (27), 10952-10957, 2013 | 40 | 2013 |
Bringing Macrolactamization Full Circle: Self-Cleaving Head-to-Tail Macrocyclization of Unprotected Peptides via Mild N-Acyl Urea Activation CA Arbour, KJ Belavek, R Tariq, S Mukherjee, JK Tom, A Isidro-Llobet, ... The Journal of Organic Chemistry 84 (2), 1035-1041, 2018 | 22 | 2018 |
Synthesis and bioactivity of diastereomers of the virulence lanthipeptide cytolysin S Mukherjee, L Huo, GN Thibodeaux, WA Van Der Donk Organic letters 18 (23), 6188-6191, 2016 | 20 | 2016 |
Phosphine-dependent photoinitiation of alkyl thiols under near-UV light facilitates user-friendly peptide desulfurization NM Venneti, G Samala, RMI Morsy, LG Mendoza, A Isidro-Llobet, JK Tom, ... Journal of the American Chemical Society 145 (2), 1053-1061, 2023 | 15 | 2023 |
Use of the dehydrophos biosynthetic enzymes to prepare antimicrobial analogs of alaphosphin DJ Bougioukou, CP Ting, SC Peck, S Mukherjee, WA Van Der Donk Organic & biomolecular chemistry 17 (4), 822-829, 2019 | 9 | 2019 |
Development of Two Synthetic Approaches to an APJ Receptor Agonist Containing a Tetra-ortho-Substituted Biaryl Pyridone MJ Goldfogel, CR Jamison, SA Savage, MW Haley, S Mukherjee, ... Organic Process Research & Development 26 (3), 624-634, 2021 | 5 | 2021 |
Chemistry in Water Reproducibility Study: Learnings from a Precompetitive, Multicompany Collaboration RJ Fox, JD Bailey, JV Obligacion, N Borlinghaus, WM Braje, X Li, ... Organic Process Research & Development 28 (4), 978-1002, 2024 | 3 | 2024 |
Process Development of a Macrocyclic Peptide Inhibitor of PD-L1 S Mukherjee, A Rogers, G Creech, C Hang, A Ramirez, M Dummeldinger, ... The Journal of Organic Chemistry, 2024 | 1 | 2024 |
Challenges with the Synthesis of a Macrocyclic Thioether Peptide: From Milligram to Multigram Using Solid Phase Peptide Synthesis (SPPS) J Kempson, R Zhao, J Pawluczyk, B Wang, H Zhang, X Hou, MP Allen, ... The Journal of Organic Chemistry, 2024 | 1 | 2024 |
Process Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis I Kekessie, K Wegner, I Martinez, ME Kopach, TD White, JK Tom, ... The Journal of Organic Chemistry 89 (7), 4261-4282, 2024 | 1 | 2024 |
Mechanistic and synthetic studies on the prochlorosin and cytolysin families of lanthipeptides S Mukherjee University of Illinois at Urbana-Champaign, 2015 | 1 | 2015 |
Novel synthetic options towards the manufacture of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6-methyl … N Cuniere, Y Fan, S Kolotuchin, S Mukherjee, EM Simmons, A SINGH, ... | | 2024 |
Process toward the manufacture of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6-methyl-1, 4, 7, 8, 9, 10 … S Mukherjee, WP Gallagher, CR Jamison, S Kolotuchin, A Singh, ... US Patent App. 18/031,277, 2023 | | 2023 |
Novel synthetic options towards the manufacture of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6-methyl … N Cuniere, Y Fan, S Kolutuchin, S Mukherjee, EM Simmons, A Singh, ... US Patent App. 17/602,059, 2022 | | 2022 |
New synthetic possibilities towards the production of (6r, 10s)-10-{4-[5-chloro-2-(4-chloro-1h-1, 2, 3-triazol-1-yl) phenyl]-6-oxo-1 (6h)-pyrimidinyl}-1-(difluoromethyl)-6 … N Cuniere, Y Fan, S Kolotuchin, S Mukherjee, EM Simmons, A Singh, ... | | 2021 |