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HUGO MUÑOZ-HERNÁNDEZ
HUGO MUÑOZ-HERNÁNDEZ
Senior Scientist
Verified email at mol.biol.ethz.ch - Homepage
Title
Cited by
Cited by
Year
RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex
F Martino, M Pal, H Muñoz-Hernández, CF Rodríguez, R Núñez-Ramírez, ...
Nature communications 9 (1), 1501, 2018
722018
Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1–RuvBL2 complex
A López-Perrote, H Muñoz-Hernández, D Gil, O Llorca
Nucleic acids research 40 (21), 11086-11099, 2012
692012
Triazolopyrimidines are microtubule-stabilizing agents that bind the Vinca inhibitor site of tubulin
G Sáez-Calvo, A Sharma, F de Asís Balaguer, I Barasoain, ...
Cell chemical biology 24 (6), 737-750. e6, 2017
652017
The structure of the R2TP complex defines a platform for recruiting diverse client proteins to the HSP90 molecular chaperone system
A Rivera-Calzada, M Pal, H Munoz-Hernandez, JR Luque-Ortega, ...
Structure 25 (7), 1145-1152. e4, 2017
592017
Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM
H Muñoz-Hernández, M Pal, CF Rodríguez, R Fernandez-Leiro, ...
Science advances 5 (5), eaaw1616, 2019
382019
Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone
M Pal, H Muñoz-Hernandez, D Bjorklund, L Zhou, G Degliesposti, ...
Cell Reports 36 (1), 2021
242021
Structure and assembly of the PI3K-like protein kinases (PIKKs) revealed by electron microscopy
A Rivera-Calzada, A López-Perrote, R Melero, J Boskovic, ...
Aims Biophysics 2 (2), 36-57, 2015
232015
Advances on the Structure of the R2TP/Prefoldin-like Complex
H Muñoz-Hernández, M Pal, CF Rodríguez, C Prodromou, LH Pearl, ...
Prefoldins: the new chaperones, 73-83, 2018
162018
The structure of a polyketide synthase bimodule core
YU Tittes, DA Herbst, SFX Martin, H Munoz-Hernandez, RP Jakob, ...
Science Advances 8 (38), eabo6918, 2022
102022
Clinical Heterogeneity and Different Phenotypes in Patients with SETD2 Variants: 18 New Patients and Review of the Literature
A Parra, R Rabin, J Pappas, P Pascual, M Cazalla, P Arias, ...
Genes 14 (6), 1179, 2023
32023
Closure of the gamma-tubulin ring complex by CDK5RAP2 activates microtubule nucleation
Y Xu, H Munoz-Hernandez, R Krutyholowa, F Marxer, F Cetin, ...
bioRxiv, 2023.12. 14.571518, 2023
32023
Modeling of a 14 kDa RUVBL2-binding domain with medium resolution cryo-EM density
CF Rodríguez, M Pal, H Munoz-Hernandez, LH Pearl, O Llorca
Journal of Chemical Information and Modeling 60 (5), 2541-2551, 2020
32020
Author Correction: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex
F Martino, M Pal, H Muñoz-Hernández, CF Rodríguez, R Núñez-Ramírez, ...
Nature communications 9 (1), 1-1, 2018
2018
Structural biology and characterization of the human R2TP, an HSP90 co-chaperone complex
H Muñoz-Hernández
CSIC-Centro de Investigaciones Biológicas Margarita Salas (CIB), 2017
2017
Triazolopyrimidines stabilize microtubules by binding to the vinca inhibitor site of tubulin
G Sáez-Calvo, A Sharma, F de Asís Balaguer, I Barasoain, ...
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