| Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial EWFW Alton, DK Armstrong, D Ashby, KJ Bayfield, D Bilton, ... The Lancet Respiratory Medicine 3 (9), 684-691, 2015 | 505 | 2015 |
| CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression SC Hyde, IA Pringle, S Abdullah, AE Lawton, LA Davies, A Varathalingam, ... Nature biotechnology 26 (5), 549-551, 2008 | 372 | 2008 |
| Toward gene therapy for cystic fibrosis using a lentivirus pseudotyped with Sendai virus envelopes K Mitomo, U Griesenbach, M Inoue, L Somerton, C Meng, E Akiba, ... Molecular therapy 18 (6), 1173-1182, 2010 | 166 | 2010 |
| Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis EWFW Alton, JM Beekman, AC Boyd, J Brand, MS Carlon, MM Connolly, ... Thorax 72 (2), 137-147, 2017 | 163 | 2017 |
| The biofiltration of indoor air: implications for air quality A Darlington1*, M Chan2, D Malloch3, C Pilger2, MA Dixon1 Indoor air 10 (1), 39-46, 2000 | 159 | 2000 |
| Assessment of F/HN-pseudotyped lentivirus as a clinically relevant vector for lung gene therapy U Griesenbach, M Inoue, C Meng, R Farley, M Chan, NK Newman, ... American journal of respiratory and critical care medicine 186 (9), 846-856, 2012 | 118 | 2012 |
| Sendai virus-mediated CFTR gene transfer to the airway epithelium S Ferrari, U Griesenbach, A Iida, R Farley, AM Wright, J Zhu, ... Gene therapy 14 (19), 1371-1379, 2007 | 70 | 2007 |
| Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import FM Munkonge, V Amin, SC Hyde, AM Green, IA Pringle, DR Gill, ... Journal of biological chemistry 284 (39), 26978-26987, 2009 | 44 | 2009 |
| A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients … EWFW Alton, DK Armstrong, D Ashby, KJ Bayfield, D Bilton, ... | 39 | 2016 |
| Adenovirus-mediated in utero expression of CFTR does not improve survival of CFTR knockout mice LA Davies, A Varathalingam, H Painter, AE Lawton, SG Sumner-Jones, ... Molecular Therapy 16 (5), 812-818, 2008 | 38 | 2008 |
| The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways U Griesenbach, C Meng, R Farley, MY Wasowicz, FM Munkonge, M Chan, ... Biomaterials 31 (9), 2665-2672, 2010 | 37 | 2010 |
| Cyanide levels found in infected cystic fibrosis sputum inhibit airway ciliary function C Nair, A Shoemark, M Chan, S Ollosson, M Dixon, C Hogg, EWFW Alton, ... European Respiratory Journal 44 (5), 1253-1261, 2014 | 30 | 2014 |
| Expression and maturation of Sendai virus vector-derived CFTR protein: functional and biochemical evidence using a GFP-CFTR fusion protein H Ban, M Inoue, U Griesenbach, F Munkonge, M Chan, A Iida, E Alton, ... Gene therapy 14 (24), 1688-1694, 2007 | 27 | 2007 |
| Limitations of the murine nose in the development of nonviral airway gene transfer U Griesenbach, SG Sumner-Jones, E Holder, FM Munkonge, ... American journal of respiratory cell and molecular biology 43 (1), 46-54, 2010 | 26 | 2010 |
| The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins MC Paul-Smith, KM Pytel, JF Gelinas, J McIntosh, I Pringle, L Davies, ... Gene Therapy 25 (5), 345-358, 2018 | 15 | 2018 |
| Ex vivo and in vivo lentivirus-mediated transduction of airway epithelial progenitor cells G Leoni, M Y Wasowicz, M Chan, C Meng, R Farley, S L Brody, M Inoue, ... Current gene therapy 15 (6), 581-590, 2015 | 9 | 2015 |
| T2 Lentivirus GM-CSF gene therapy ameliorates autoimmune pulmonary alveolar proteinosis H Lund-Palau, C Meng, A Pilou, N Atsumi, A Bhargava, M Chan, A Byrne, ... Thorax 73 (Suppl 4), A1-A2, 2018 | 5 | 2018 |
| Introduction and background EWFW Alton, DK Armstrong, D Ashby, KJ Bayfield, D Bilton, ... A randomised, double-blind, placebo-controlled trial of repeated …, 2016 | 1 | 2016 |
| Methods: clinical trial design and outcome measures EWFW Alton, DK Armstrong, D Ashby, KJ Bayfield, D Bilton, ... A randomised, double-blind, placebo-controlled trial of repeated …, 2016 | 1 | 2016 |
| S127 Gene therapy for alpha-1-antitrypsin deficiency using a pseudotyped lentivirus vector MC Paul-Smith, JF Gelinas, K Pytel, M Chan, C Meng, L Cammack, ... Thorax 70 (Suppl 3), A72-A73, 2015 | 1 | 2015 |
