William Y. Kim, M.D.
William Y. Kim, M.D.
Professor of Medicine and Genetics, UNC
Dirección de correo verificada de med.unc.edu - Página principal
Citado por
Citado por
HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, JM Asara, ...
Science 292 (5516), 464-468, 2001
Role of VHL gene mutation in human cancer
WY Kim, WG Kaelin
Journal of Clinical Oncology 22 (24), 4991-5004, 2004
The Regulation of INK4/ARF in Cancer and Aging
WY Kim, NE Sharpless
Cell 127 (2), 265-275, 2006
Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth
K Kondo, WY Kim, M Lechpammer, WG Kaelin Jr
PLoS Biol 1 (3), e83, 2003
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ...
Cell 149 (2), 307-321, 2012
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
JS Damrauer, KA Hoadley, DD Chism, C Fan, CJ Tiganelli, SE Wobker, ...
Proceedings of the National Academy of Sciences 111 (8), 3110-3115, 2014
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
H Ji, D Li, L Chen, T Shimamura, S Kobayashi, K McNamara, U Mahmood, ...
Cancer cell 9 (6), 485-495, 2006
Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival after neoadjuvant chemotherapy
R Seiler, HAD Ashab, N Erho, BWG van Rhijn, B Winters, J Douglas, ...
European urology 72 (4), 544-554, 2017
Interleukin-6: a candidate mediator of human prostate cancer morbidity
DA Twillie, MA Eisenberger, MA Carducci, WS Hseih, WY Kim, ...
Urology 45 (3), 542-549, 1995
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production
M Safran, WY Kim, F O'Connell, L Flippin, V Günzler, JW Horner, ...
Proceedings of the National Academy of Sciences 103 (1), 105-110, 2006
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail
AJ Evans, RC Russell, O Roche, TN Burry, JE Fish, VWK Chow, WY Kim, ...
Molecular and cellular biology 27 (1), 157-169, 2007
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma
CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ...
Cell reports 23 (1), 313-326. e5, 2018
Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors
J Carretero, T Shimamura, K Rikova, AL Jackson, MD Wilkerson, ...
Cancer cell 17 (6), 547-559, 2010
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
WY Kim, M Safran, MRM Buckley, BL Ebert, J Glickman, M Bosenberg, ...
The EMBO journal 25 (19), 4650-4662, 2006
The von Hippel–Lindau tumor suppressor protein: new insights into oxygen sensing and cancer
W Kim, WG Kaelin Jr
Current opinion in genetics & development 13 (1), 55-60, 2003
Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma
CL Cowey, C Amin, RS Pruthi, EM Wallen, ME Nielsen, G Grigson, ...
Journal of Clinical Oncology 28 (9), 1502, 2010
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells
M Ohh, WY Kim, JJ Moslehi, Y Chen, V Chau, MA Read, WG Kaelin
EMBO reports 3 (2), 177-182, 2002
Regulation of endocytosis via the oxygen-sensing pathway
Y Wang, O Roche, MS Yan, G Finak, AJ Evans, JL Metcalf, BE Hast, ...
Nature medicine 15 (3), 319-324, 2009
pVHL acts as an adaptor to promote the inhibitory phosphorylation of the NF-κB agonist Card9 by CK2
H Yang, YA Minamishima, Q Yan, S Schlisio, BL Ebert, X Zhang, L Zhang, ...
Molecular cell 28 (1), 15-27, 2007
State of the science: an update on renal cell carcinoma
E Jonasch, PA Futreal, IJ Davis, ST Bailey, WY Kim, J Brugarolas, ...
Molecular Cancer Research 10 (7), 859-880, 2012
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20