| Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ... Nature biotechnology 35 (12), 1179-1187, 2017 | 472 | 2017 |
| Partial DNA-guided Cas9 enables genome editing with reduced off-target activity H Yin, CQ Song, S Suresh, SY Kwan, Q Wu, S Walsh, J Ding, RL Bogorad, ... Nature chemical biology 14 (3), 311-316, 2018 | 228 | 2018 |
| KRAS (but not BRAF) mutations in ovarian serous borderline tumour are associated with recurrent low‐grade serous carcinoma YT Tsang, MT Deavers, CC Sun, SY Kwan, E Kuo, A Malpica, SC Mok, ... The Journal of pathology 231 (4), 449-456, 2013 | 129 | 2013 |
| A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver C Zheng, SQ Liang, B Liu, P Liu, SY Kwan, SA Wolfe, W Xue Molecular Therapy 30 (3), 1343-1351, 2022 | 60 | 2022 |
| Poor survival with wild-type TP53 ovarian cancer? KK Wong, DI Izaguirre, SY Kwan, ER King, MT Deavers, AK Sood, ... Gynecologic oncology 130 (3), 565-569, 2013 | 54 | 2013 |
| Depletion of TRRAP induces p53‐independent senescence in liver cancer by down‐regulating mitotic genes SY Kwan, A Sheel, CQ Song, XO Zhang, T Jiang, H Dang, Y Cao, ... Hepatology 71 (1), 275-290, 2020 | 52 | 2020 |
| Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas EK Crane, SY Kwan, DI Izaguirre, YTM Tsang, LK Mullany, Z Zu, ... PloS one 10 (8), e0135101, 2015 | 44 | 2015 |
| PAX2 expression in ovarian cancer H Song, SY Kwan, DI Izaguirre, Z Zu, YT Tsang, CS Tung, ER King, ... International journal of molecular sciences 14 (3), 6090-6105, 2013 | 40 | 2013 |
| Foxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex J Wu, SW Lee, X Zhang, F Han, SY Kwan, X Yuan, WL Yang, YS Jeong, ... Oncogene 32 (1), 78-85, 2013 | 40 | 2013 |
| Loss of ARID1A expression leads to sensitivity to ROS-inducing agent elesclomol in gynecologic cancer cells SY Kwan, X Cheng, YTM Tsang, JS Choi, SY Kwan, DI Izaguirre, ... Oncotarget 7 (35), 56933, 2016 | 38 | 2016 |
| CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling H Mou, DM Ozata, JL Smith, A Sheel, SY Kwan, S Hough, A Kucukural, ... Genome Medicine 11, 1-11, 2019 | 14 | 2019 |
| YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte‐like cells JL Smith, TC Rodríguez, H Mou, SY Kwan, H Pratt, XO Zhang, Y Cao, ... Hepatology 73 (3), 1011-1027, 2021 | 13 | 2021 |
| The role of GDF15 in regulating the canonical pathways of the tumor microenvironment in wild-type p53 ovarian tumor and its response to chemotherapy DI Izaguirre, CW Ng, SY Kwan, EH Kun, YTM Tsang, DM Gershenson, ... Cancers 12 (10), 3043, 2020 | 12 | 2020 |
| Development of a flexible split prime editor using truncated reverse transcriptase C Zheng, SQ Liang, B Liu, P Liu, SY Kwan, SA Wolfe, W Xue BioRxiv, 2021.08. 26.457801, 2021 | 5 | 2021 |
| Multi-omics characterization of mouse hepatoblastoma identifies novel YAP1 target genes. TC Rodríguez, S Kwan, JL Smith, S Dadafarin, CH Wu, EJ Sontheimer, ... Hepatology (Baltimore, Md.), 2022 | 1 | 2022 |
| GDF15 as a serum marker of cisplatin response in ovarian cancer cells. DI Izaguirre, SY Kwan, Z Zu, YT Tsang-Lee, KK Wong Cancer Research 73 (8_Supplement), 3474-3474, 2013 | 1 | 2013 |
| A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors Z Chen, SY Kwan, A Mir, M Hazeltine, M Shin, SQ Liang, IL Chan, K Kelly, ... The CRISPR Journal 6 (6), 570-582, 2023 | | 2023 |
| Multiomics characterization of mouse hepatoblastoma identifies yes‐associated protein 1 target genes TC Rodríguez, SY Kwan, JL Smith, S Dadafarin, CH Wu, EJ Sontheimer, ... Hepatology 78 (1), 58-71, 2023 | | 2023 |
| Integrating CRISPR screening with tumor genomic analyses to identify therapeutic targets in hepatocellular carcinomas (HCC) independent of P53. A Sheel, SY Kwan, W Xue Journal of Clinical Oncology 37 (15_suppl), e14659-e14659, 2019 | | 2019 |
| Abstract NTOC-114: ARID1A DEFICIENCY IN OVARIAN CLEAR CELL CARCINOMAS UP–REGULATES OXIDATIVE STRESS AND SENSITIZES CELLS TO ROS–INDUCING AGENTS SY Kwan, X Cheng, SY Kwan, DI Izaguirre, YTM Tsang, JS Choi, ... Clinical Cancer Research 23 (11_Supplement), NTOC-114-NTOC-114, 2017 | | 2017 |
Kwong-Kwok WongProfessor, Department of Gynecologic Oncology and Reprod Med, UT MD Anderson Cancer CenterDirección de correo verificada de mdanderson.org
