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Adam Dingens
Adam Dingens
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Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
cell 182 (5), 1295-1310. e20, 2020
18462020
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
10392021
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ...
Science 371 (6531), 850-854, 2021
7332021
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays
KHD Crawford, R Eguia, AS Dingens, AN Loes, KD Malone, CR Wolf, ...
Viruses 12 (5), 513, 2020
7122020
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate
A Addetia, KHD Crawford, A Dingens, H Zhu, P Roychoudhury, ML Huang, ...
Journal of clinical microbiology 58 (11), 10.1128/jcm. 02107-20, 2020
5972020
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
TN Starr, AJ Greaney, AS Dingens, JD Bloom
Cell Reports Medicine 2 (4), 2021
4652021
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
3932021
Dynamics of neutralizing antibody titers in the months after severe acute respiratory syndrome coronavirus 2 infection
KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, ...
The Journal of infectious diseases 223 (2), 197-205, 2021
2952021
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
Nature microbiology 6 (10), 1233-1244, 2021
2392021
Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
BioRxiv, 2021
1272021
Mapping mutational effects along the evolutionary landscape of HIV envelope
HK Haddox*, AS Dingens*, SK Hilton, J Overbaugh, JD Bloom
Elife 7, e34420, 2018
1112018
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization
R Kong*, H Duan*, Z Sheng*, K Xu*, P Acharya*, X Chen*, C Cheng*, ...
Cell 178 (3), 567-584. e19, 2019
1042019
Restriction of HIV-1 escape by a highly broad and potent neutralizing antibody
P Schommers, H Gruell, ME Abernathy, MK Tran, AS Dingens, HB Gristick, ...
Cell 180 (3), 471-489. e22, 2020
1022020
Experimental estimation of the effects of all amino-acid mutations to HIV’s envelope protein on viral replication in cell culture
HK Haddox, AS Dingens, JD Bloom
PLoS pathogens 12 (12), e1006114, 2016
942016
Comprehensive mapping of HIV-1 escape from a broadly neutralizing antibody
AS Dingens, HK Haddox, J Overbaugh, JD Bloom
Cell host & microbe 21 (6), 777-787. e4, 2017
922017
Bacterial vaginosis and adverse outcomes among full-term infants: a cohort study
AS Dingens, TS Fairfortune, S Reed, C Mitchell
BMC pregnancy and childbirth 16, 1-8, 2016
842016
An antigenic atlas of HIV-1 escape from broadly neutralizing antibodies distinguishes functional and structural epitopes
AS Dingens, D Arenz, H Weight, J Overbaugh, JD Bloom
Immunity 50 (2), 520-532. e3, 2019
782019
Cooperation between distinct viral variants promotes growth of H3N2 influenza in cell culture
KS Xue, KA Hooper, AR Ollodart, AS Dingens, JD Bloom
Elife 5, e13974, 2016
782016
Serological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreak
AS Dingens, KHD Crawford, A Adler, SL Steele, K Lacombe, R Eguia, ...
Nature communications 11 (1), 4378, 2020
692020
HIV-specific CD4-induced antibodies mediate broad and potent antibody-dependent cellular cytotoxicity activity and are commonly detected in plasma from HIV-infected humans
KL Williams, V Cortez, AS Dingens, JS Gach, S Rainwater, JF Weis, ...
EBioMedicine 2 (10), 1464-1477, 2015
642015
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