| The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space R Perez-Gonzalez, SA Gauthier, A Kumar, E Levy Journal of Biological Chemistry 287 (51), 43108-43115, 2012 | 379 | 2012 |
| Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome P D’Acunzo, R Pérez-González, Y Kim, T Hargash, C Miller, MJ Alldred, ... Science advances 7 (7), eabe5085, 2021 | 155 | 2021 |
| Leptin induces proliferation of neuronal progenitors and neuroprotection in a mouse model of Alzheimer's disease R Perez-Gonzalez, D Antequera, T Vargas, C Spuch, M Bolós, E Carro Journal of Alzheimer's Disease 24 (s2), 17-25, 2011 | 126 | 2011 |
| The ANKK1 Kinase Gene and Psychiatric Disorders G Ponce, R Pérez-González, M Aragüés, T Palomo, ... Neurotoxicity research 16, 50-59, 2009 | 114 | 2009 |
| Enhanced exosome secretion in Down syndrome brain-a protective mechanism to alleviate neuronal endosomal abnormalities SA Gauthier, R Pérez-González, A Sharma, FK Huang, MJ Alldred, ... Acta neuropathologica communications 5, 1-13, 2017 | 111 | 2017 |
| Phosphodiesterase 7 inhibitor reduced cognitive impairment and pathological hallmarks in a mouse model of Alzheimer's disease R Perez-Gonzalez, C Pascual, D Antequera, M Bolos, M Redondo, ... Neurobiology of aging 34 (9), 2133-2145, 2013 | 101 | 2013 |
| Apolipoprotein E4 genotype compromises brain exosome production KY Peng, R Pérez-González, MJ Alldred, CN Goulbourne, ... Brain 142 (1), 163-175, 2019 | 91 | 2019 |
| Intranasal delivery of plasma and platelet growth factors using PRGF-Endoret system enhances neurogenesis in a mouse model of Alzheimer’s disease E Anitua, C Pascual, R Pérez-Gonzalez, D Antequera, S Padilla, G Orive, ... PloS one 8 (9), e73118, 2013 | 81 | 2013 |
| Leptin gene therapy attenuates neuronal damages evoked by amyloid-β and rescues memory deficits in APP/PS1 mice R Perez-Gonzalez, MX Alvira-Botero, O Robayo, D Antequera, M Garzón, ... Gene therapy 21 (3), 298-308, 2014 | 80 | 2014 |
| A method for isolation of extracellular vesicles and characterization of exosomes from brain extracellular space R Pérez-González, SA Gauthier, A Kumar, M Saito, M Saito, E Levy Exosomes and Microvesicles: Methods and Protocols, 139-151, 2017 | 79 | 2017 |
| Megalin interacts with APP and the intracellular adapter protein FE65 in neurons X Alvira-Botero, R Pérez-Gonzalez, C Spuch, T Vargas, D Antequera, ... Molecular and Cellular Neuroscience 45 (3), 306-315, 2010 | 79 | 2010 |
| The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine J Hoenicka, A Quiñones-Lombraña, L España-Serrano, X Alvira-Botero, ... Biological psychiatry 67 (1), 3-11, 2010 | 79 | 2010 |
| VEGF-releasing biodegradable nanospheres administered by craniotomy: a novel therapeutic approach in the APP/Ps1 mouse model of Alzheimer's disease E Herrán, R Pérez-González, M Igartua, JL Pedraz, E Carro, ... Journal of Controlled Release 170 (1), 111-119, 2013 | 78 | 2013 |
| Intranasal PRGF-Endoret enhances neuronal survival and attenuates NF-κB-dependent inflammation process in a mouse model of Parkinson's disease E Anitua, C Pascual, R Pérez-Gonzalez, G Orive, E Carro Journal of Controlled Release 203, 170-180, 2015 | 63 | 2015 |
| Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches J Extracell Vesicles 13 (2), e12404, 2024 | 54 | 2024 |
| Serum neurofilament light chain levels reflect cortical neurodegeneration in de novo Parkinson's disease F Sampedro, R Pérez-González, S Martínez-Horta, J Marín-Lahoz, ... Parkinsonism & Related Disorders 74, 43-49, 2020 | 45 | 2020 |
| Enhanced hippocampal neurogenesis in APP/Ps1 mouse model of Alzheimer’s disease after implantation of VEGF-loaded PLGA nanospheres E Herran, R Perez-Gonzalez, M Igartua, JL Pedraz, E Carro, ... Current Alzheimer Research 12 (10), 932-940, 2015 | 41 | 2015 |
| Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes J Pacheco-Quinto, D Clausen, R Pérez-González, H Peng, A Meszaros, ... The FASEB Journal 33 (3), 3758, 2019 | 36 | 2019 |
| Extracellular vesicles: where the amyloid precursor protein carboxyl‐terminal fragments accumulate and amyloid‐β oligomerizes R Pérez‐González, Y Kim, C Miller, J Pacheco‐Quinto, EA Eckman, ... The FASEB Journal 34 (9), 12922, 2020 | 34 | 2020 |
| Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues P D’Acunzo, Y Kim, JM Ungania, R Pérez-González, CN Goulbourne, ... Nature Protocols 17 (11), 2517-2549, 2022 | 33 | 2022 |
