| Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer S Krishna, FJ Lowery, AR Copeland, E Bahadiroglu, R Mukherjee, L Jia, ... Science 370 (6522), 1328-1334, 2020 | 329 | 2020 |
| Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy CA Klebanoff, JG Crompton, AJ Leonardi, TN Yamamoto, SS Chandran, ... JCI insight 2 (23), 2017 | 182 | 2017 |
| T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy TN Yamamoto, PH Lee, SK Vodnala, D Gurusamy, RJ Kishton, Z Yu, ... The Journal of clinical investigation 129 (4), 1551-1565, 2019 | 136 | 2019 |
| The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity S Gautam, J Fioravanti, W Zhu, JB Le Gall, P Brohawn, NE Lacey, J Hu, ... Nature immunology 20 (3), 337-349, 2019 | 135 | 2019 |
| Multi-phenotype CRISPR-Cas9 screen identifies p38 kinase as a target for adoptive immunotherapies D Gurusamy, AN Henning, TN Yamamoto, Z Yu, N Zacharakis, S Krishna, ... Cancer cell 37 (6), 818-833. e9, 2020 | 114 | 2020 |
| The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cells MN Thobe, D Gurusamy, P Pathrose, SE Waltz Oncogene 29 (2), 214-226, 2010 | 76 | 2010 |
| Myeloid-specific expression of Ron receptor kinase promotes prostate tumor growth D Gurusamy, JK Gray, P Pathrose, RM Kulkarni, FD Finkleman, SE Waltz Cancer research 73 (6), 1752-1763, 2013 | 69 | 2013 |
| Novel “elements” of immune suppression within the tumor microenvironment D Gurusamy, D Clever, R Eil, NP Restifo Cancer immunology research 5 (6), 426-433, 2017 | 64 | 2017 |
| Ron receptor tyrosine kinase negatively regulates TNFα production in alveolar macrophages by inhibiting NF-κB activity and ADAM17 production NM Nikolaidis, JK Gray, D Gurusamy, W Fox, WD Stuart, N Huber, ... Shock 33 (2), 197-204, 2010 | 64 | 2010 |
| Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells PH Lee, TN Yamamoto, D Gurusamy, M Sukumar, Z Yu, J Hu-Li, ... Journal of Experimental Medicine 216 (11), 2619-2634, 2019 | 57 | 2019 |
| Generation of tumor antigen-specific iPSC-derived thymic emigrants using a 3D thymic culture system R Vizcardo, ND Klemen, SMR Islam, D Gurusamy, N Tamaoki, D Yamada, ... Cell reports 22 (12), 3175-3190, 2018 | 46 | 2018 |
| Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade DC Palmer, BR Webber, Y Patel, MJ Johnson, CM Kariya, WS Lahr, ... Med 3 (10), 682-704. e8, 2022 | 44 | 2022 |
| CD4+ T cell help selectively enhances high-avidity tumor antigen-specific CD8+ T cells Z Zhu, SM Cuss, V Singh, D Gurusamy, JL Shoe, R Leighty, V Bronte, ... The Journal of Immunology 195 (7), 3482-3489, 2015 | 43 | 2015 |
| Lipocalin-2 (Lcn-2) attenuates polymicrobial sepsis with LPS preconditioning (LPS tolerance) in FcGRIIb deficient lupus mice T Ondee, J Gillen, P Visitchanakun, P Somparn, J Issara-Amphorn, ... Cells 8 (9), 1064, 2019 | 41 | 2019 |
| LPS tolerance inhibits cellular respiration and induces global changes in the macrophage secretome J Gillen, T Ondee, D Gurusamy, J Issara-Amphorn, NP Manes, SH Yoon, ... Biomolecules 11 (2), 164, 2021 | 39 | 2021 |
| The Ron receptor promotes prostate tumor growth in the TRAMP mouse model MN Thobe, JK Gray, D Gurusamy, AM Paluch, PK Wagh, P Pathrose, ... Oncogene 30 (50), 4990-4998, 2011 | 34 | 2011 |
| Bile acid-induced “Minority MOMP” promotes esophageal carcinogenesis while maintaining apoptotic resistance via Mcl-1 Y Xu, DR Surman, L Diggs, S Xi, S Gao, D Gurusamy, K McLoughlin, ... Oncogene 39 (4), 877-890, 2020 | 27 | 2020 |
| Ron receptor signaling is protective against DSS-induced colitis in mice RM Kulkarni, WD Stuart, D Gurusamy, SE Waltz American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (12 …, 2014 | 25 | 2014 |
| Hepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesis D Gurusamy, SJ Ruiz-Torres, AL Johnson, DA Smith, SE Waltz Mechanisms of development 133, 11-22, 2014 | 22 | 2014 |
| Identification of neoantigen-reactive T lymphocytes in the peripheral blood of a patient with glioblastoma V Leko, G Cafri, R Yossef, B Paria, V Hill, D Gurusamy, Z Zheng, ... Journal for Immunotherapy of Cancer 9 (7), 2021 | 20 | 2021 |
Nicholas P Restifo, MDCellular Immunotherapy ExplorerVerified email at marbletx.com
