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Jonai Pujol Gimenez
Jonai Pujol Gimenez
Dirección de correo verificada de ibmm.unibe.ch
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Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application
G Gyimesi, J Pujol-Giménez, Y Kanai, MA Hediger
Pflügers Archiv-European Journal of Physiology 472 (9), 1177-1206, 2020
712020
Could GLUT12 be a potential therapeutic target in cancer treatment? A preliminary report
J Pujol-Gimenez, FP de Heredia, MA Idoate, R Airley, MP Lostao, ...
Journal of Cancer 6 (2), 139, 2015
412015
A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters
J Pujol-Giménez, MA Hediger, G Gyimesi
Scientific Reports 7 (1), 6194, 2017
302017
The facilitative glucose transporter GLUT12: what do we know and what would we like to know?
J Pujol-Giménez, J Barrenetxe, P González-Muniesa, MP Lostao
Journal of physiology and biochemistry 69, 325-333, 2013
282013
Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism
AB Stergachis, J Pujol‐Giménez, G Gyimesi, D Fuster, G Albano, ...
Annals of neurology 85 (6), 921-926, 2019
262019
Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods
J Pujol-Giménez, A Pérez, AM Reyes, DDF Loo, MP Lostao
American Journal of Physiology-Cell Physiology 308 (12), C1008-C1022, 2015
252015
Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1
P Kandasamy, I Zlobec, DT Nydegger, J Pujol‐Giménez, R Bhardwaj, ...
Molecular oncology 15 (10), 2782-2800, 2021
242021
Reassessment of the transport mechanism of the human zinc transporter SLC39A2
MC Franz, J Pujol-Giménez, N Montalbetti, M Fernandez-Tenorio, ...
Biochemistry 57 (26), 3976-3986, 2018
222018
Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds
C Manatschal, J Pujol-Gimenez, M Poirier, JL Reymond, MA Hediger, ...
Elife 8, e51913, 2019
212019
Expression of the glucose transporter GLUT12 in Alzheimer's disease patients
J Pujol-Gimenez, E Martisova, A Perez-Mediavilla, MP Lostao, ...
Journal of Alzheimer's Disease 42 (1), 97-101, 2014
202014
Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2)
G Gyimesi, G Albano, DG Fuster, MA Hediger, J Pujol-Giménez
Journal of biological chemistry 294 (20), 8046-8063, 2019
172019
Electrophysiological characterization of a diverse group of sugar transporters from Trichoderma reesei
S Havukainen, J Pujol-Giménez, M Valkonen, A Westerholm-Parvinen, ...
Scientific reports 11 (1), 14678, 2021
112021
Inhibitors of human divalent metal transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 fragment library
J Pujol‐Giménez, M Poirier, S Bühlmann, C Schuppisser, R Bhardwaj, ...
ChemMedChem 16 (21), 3306-3314, 2021
92021
The hydroxyl side chain of a highly conserved serine residue is required for cation selectivity and substrate transport in the glial glutamate transporter GLT-1/SLC1A2
A Simonin, N Montalbetti, G Gyimesi, J Pujol-Giménez, MA Hediger
Journal of Biological Chemistry 290 (51), 30464-30474, 2015
92015
Functional characterization of a highly specific l-arabinose transporter from Trichoderma reesei
S Havukainen, J Pujol-Giménez, M Valkonen, MA Hediger, CP Landowski
Microbial cell factories 20, 1-20, 2021
82021
Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation
M Poirier, J Pujol-Giménez, C Manatschal, S Bühlmann, A Embaby, ...
RSC Medicinal Chemistry 11 (9), 1023-1031, 2020
62020
The allelic variant A391T of metal ion transporter ZIP8 (SLC39A8) leads to hypotension and enhanced insulin resistance
SN Verouti, J Pujol-Giménez, P Bermudez-Lekerika, L Scherler, ...
Frontiers in physiology 13, 912277, 2022
32022
Applications of the Microscale Thermophoresis Binding Assay in COVID-19 Research
DT Nydegger, J Pujol-Giménez, P Kandasamy, B Vogt, MA Hediger
Viruses 15 (7), 1432, 2023
22023
Functional Characterization of the Lysosomal Peptide/Histidine Transporter PHT1 (SLC15A4) by Solid Supported Membrane Electrophysiology (SSME)
J Pujol-Giménez, MA Hediger
Preprints, 2023
2023
Dominant‐negative variant in SLC1A4 causes an autosomal dominant epilepsy syndrome
J Pujol‐Giménez, G Mirzaa, EE Blue, G Albano, DE Miller, A Allworth, ...
Annals of Clinical and Translational Neurology 10 (6), 1046-1053, 2023
2023
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