| Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain A Lingel, B Simon, E Izaurralde, M Sattler Nature 426 (6965), 465-469, 2003 | 634 | 2003 |
| Nucleic acid 3′-end recognition by the Argonaute2 PAZ domain A Lingel, B Simon, E Izaurralde, M Sattler Nature structural & molecular biology 11 (6), 576-577, 2004 | 457 | 2004 |
| An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED W Qi, K Zhao, J Gu, Y Huang, Y Wang, H Zhang, M Zhang, J Zhang, Z Yu, ... Nature chemical biology 13 (4), 381-388, 2017 | 289 | 2017 |
| Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors—insight into heterotrimeric IL-1 signaling complexes A Lingel, TM Weiss, M Niebuhr, B Pan, BA Appleton, C Wiesmann, ... Structure 17 (10), 1398-1410, 2009 | 255 | 2009 |
| Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination EC Dueber, AJ Schoeffler, A Lingel, JM Elliott, AV Fedorova, AM Giannetti, ... Science 334 (6054), 376-380, 2011 | 233 | 2011 |
| Cyclic green fluorescent protein produced in vivo using an artificially split PI-PfuI intein from Pyrococcus furiosus H Iwai, A Lingel, A Pluckthun Journal of Biological Chemistry 276 (19), 16548-16554, 2001 | 181 | 2001 |
| Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site HR Maun, X Wen, A Lingel, FJ de Sauvage, RA Lazarus, SJ Scales, ... Journal of biological chemistry 285 (34), 26570-26580, 2010 | 164 | 2010 |
| The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling I Bosanac, HR Maun, SJ Scales, X Wen, A Lingel, JF Bazan, ... Nature structural & molecular biology 16 (7), 691-697, 2009 | 163 | 2009 |
| The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double‐stranded RNA recognition A Lingel, B Simon, E Izaurralde, M Sattler EMBO reports 6 (12), 1149-1155, 2005 | 159 | 2005 |
| Novel modes of protein–RNA recognition in the RNAi pathway A Lingel, M Sattler Current opinion in structural biology 15 (1), 107-115, 2005 | 135 | 2005 |
| Discovery of first-in-class, potent, and orally bioavailable embryonic ectoderm development (EED) inhibitor with robust anticancer efficacy Y Huang, J Zhang, Z Yu, H Zhang, Y Wang, A Lingel, W Qi, J Gu, K Zhao, ... Journal of medicinal chemistry 60 (6), 2215-2226, 2017 | 102 | 2017 |
| RNAi: finding the elusive endonuclease A Lingel, E Izaurralde Rna 10 (11), 1675-1679, 2004 | 73 | 2004 |
| Structure-guided design of EED binders allosterically inhibiting the epigenetic polycomb repressive complex 2 (PRC2) methyltransferase A Lingel, M Sendzik, Y Huang, MD Shultz, J Cantwell, MP Dillon, X Fu, ... Journal of Medicinal Chemistry 60 (1), 415-427, 2017 | 61 | 2017 |
| Discovery and molecular basis of a diverse set of polycomb repressive complex 2 inhibitors recognition by EED L Li, H Zhang, M Zhang, M Zhao, L Feng, X Luo, Z Gao, Y Huang, ... PLoS One 12 (1), e0169855, 2017 | 56 | 2017 |
| Structure of the complex between HER2 and an antibody paratope formed by side chains from tryptophan and serine RD Fisher, M Ultsch, A Lingel, G Schaefer, L Shao, S Birtalan, SS Sidhu, ... Journal of molecular biology 402 (1), 217-229, 2010 | 51 | 2010 |
| Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation E Bourhis, A Lingel, Q Phung, WJ Fairbrother, AG Cochran Biochemistry 48 (29), 6783-6793, 2009 | 42 | 2009 |
| The C-terminal region of Ge-1 presents conserved structural features required for P-body localization M Jinek, A Eulalio, A Lingel, S Helms, E Conti, E Izaurralde Rna 14 (10), 1991-1998, 2008 | 35 | 2008 |
| Comprehensive and High‐Throughput Exploration of Chemical Space Using Broadband 19F NMR‐Based Screening A Lingel, A Vulpetti, T Reinsperger, A Proudfoot, R Denay, A Frommlet, ... Angewandte Chemie International Edition 59 (35), 14809-14817, 2020 | 34 | 2020 |
| JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors E Lorthiois, M Gerspacher, KS Beyer, A Vaupel, C Leblanc, R Stringer, ... Journal of medicinal chemistry 65 (24), 16173-16203, 2022 | 33 | 2022 |
| Facilitating unambiguous NMR assignments and enabling higher probe density through selective labeling of all methyl containing amino acids A Proudfoot, AO Frank, F Ruggiu, M Mamo, A Lingel Journal of biomolecular NMR 65, 15-27, 2016 | 31 | 2016 |
