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Sylvain Broussy
Sylvain Broussy
Associate Professor of Organic Chemistry, University of Paris
Dirección de correo verificada de u-paris.fr
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Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens
JA Friest, Y Maezato, S Broussy, P Blum, DB Berkowitz
Journal of the American Chemical Society 132 (17), 5930-5931, 2010
1072010
Mn(III) Pyrophosphate as an Efficient Tool for Studying the Mode of Action of Isoniazid on the InhA Protein of Mycobacterium tuberculosis
M Nguyen, A Quémard, S Broussy, J Bernadou, B Meunier
Antimicrobial agents and chemotherapy 46 (7), 2137-2144, 2002
1002002
Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: ethanol as tunable nicotinamide reductant
S Broussy, RW Cheloha, DB Berkowitz
Organic letters 11 (2), 305-308, 2009
992009
The First Chemical Synthesis of the Core Structure of the Benzoylhydrazine−NAD Adduct, a Competitive Inhibitor of the Mycobacterium tuberculosis Enoyl Reductase
S Broussy, V Bernardes-Génisson, A Quémard, B Meunier, J Bernadou
The Journal of Organic Chemistry 70 (25), 10502-10510, 2005
642005
1H and 13C NMR Characterization of Hemiamidal Isoniazid‐NAD(H) Adducts as Possible Inhibitors Of InhA Reductase of Mycobacterium tuberculosis
S Broussy, Y Coppel, M Nguyen, J Bernadou, B Meunier
Chemistry–A European Journal 9 (9), 2034-2038, 2003
442003
Biochemical mechanism and biological effects of the inhibition of silent information regulator 1 (SIRT1) by EX-527 (SEN0014196 or selisistat)
S Broussy, H Laaroussi, M Vidal
Journal of enzyme inhibition and medicinal chemistry 35 (1), 1124-1136, 2020
382020
Guanine oxidation by electron transfer: one‐versus two‐electron oxidation mechanism
A Kupan, A Saulière, S Broussy, C Seguy, G Pratviel, B Meunier
ChemBioChem 7 (1), 125-133, 2006
382006
Combinatorial Catalysis Assisted by a Visible Enzymatic Beacon in Real Time: New Synthetically Versatile (Pseudo) Halometalation/Carbocyclizations
JA Friest, S Broussy, WJ Chung, DB Berkowitz
Angewandte Chemie (International ed. in English) 50 (38), 8895, 2011
342011
Isolation, characterization, antioxidant activity, and protein-precipitating capacity of the hydrolyzable tannin punicalagin from pomegranate yellow peel (Punica granatum)
B Oudane, D Boudemagh, M Bounekhel, W Sobhi, M Vidal, S Broussy
Journal of Molecular Structure 1156, 390-396, 2018
302018
Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the …
A Sadremomtaz, AM Ali, F Jouyandeh, S Balalaie, R Navari, S Broussy, ...
Signal transduction and targeted therapy 5 (1), 76, 2020
212020
1 H and 13C NMR characterization of pyridinium-type isoniazid–NAD adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis
S Broussy, V Bernardes-Génisson, Y Coppel, A Quémard, J Bernadou, ...
Organic & Biomolecular Chemistry 3 (4), 670-673, 2005
202005
Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid–NAD adduct
S Broussy, V Bernardes-Génisson, H Gornitzka, J Bernadou, B Meunier
Organic & Biomolecular Chemistry 3 (4), 666-669, 2005
202005
Identification of peptidic antagonists of vascular endothelial growth factor receptor 1 by scanning the binding epitopes of its ligands
L Wang, L Zhou, M Reille-Seroussi, N Gagey-Eilstein, S Broussy, T Zhang, ...
Journal of medicinal chemistry 60 (15), 6598-6606, 2017
192017
Vascular endothelial growth factor peptide ligands explored by competition assay and isothermal titration calorimetry
M Reille-Seroussi, JF Gaucher, C Desole, N Gagey-Eilstein, F Brachet, ...
Biochemistry 54 (33), 5147-5156, 2015
192015
Design and synthesis of C-terminal modified cyclic peptides as VEGFR1 antagonists
L Wang, N Gagey-Eilstein, S Broussy, M Reille-Seroussi, F Huguenot, ...
Molecules 19 (10), 15391-15407, 2014
192014
Biophysical studies of the induced dimerization of human VEGF receptor 1 binding domain by divalent metals competing with VEGF-A
JF Gaucher, M Reille-Seroussi, N Gagey-Eilstein, S Broussy, P Coric, ...
PLoS One 11 (12), e0167755, 2016
142016
Solid phase synthesis of highly substituted tetrahydropyrans by tandem ene-reaction/intramolecular sakurai cyclization
S Broussy, H Waldmann
Journal of Combinatorial Chemistry 9 (6), 1138-1143, 2007
142007
A Flexible Route Towards Five‐Membered Ring Imino Sugars and Their Novel 2‐Deoxy‐2‐fluoro Analogues
T Ayad, Y Génisson, S Broussy, M Baltas, L Gorrichon
European Journal of Organic Chemistry 2003 (15), 2903-2910, 2003
142003
Synthesis and characterization of water-soluble macrocyclic peptides stabilizing protein α-turn
L Wang, P Coric, K Zhu, WQ Liu, M Vidal, S Bouaziz, S Broussy
Organic & biomolecular chemistry 16 (3), 459-471, 2018
122018
A structural overview of vascular endothelial growth factors pharmacological ligands: from macromolecules to designed peptidomimetics
X Ye, JF Gaucher, M Vidal, S Broussy
Molecules 26 (22), 6759, 2021
102021
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Artículos 1–20