Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour‐cell‐derived heparanases CR Parish, DR Coombe, KB Jakobsen, FA Bennett, PA Underwood International journal of cancer 40 (4), 511-518, 1987 | 254 | 1987 |
The role of immunoglobulin superfamily cell adhesion molecules in cancer metastasis C Wai Wong, DE Dye, DR Coombe International journal of cell biology 2012, 2012 | 253 | 2012 |
Analysis of the inhibition of tumour metastasis by sulphated polysaccharides DR Coombe, CR Parish, IA Ramshaw, JM Snowden International Journal of Cancer 39 (1), 82-88, 1987 | 248 | 1987 |
The heparin binding PECAM-1 adhesion molecule is expressed by CD34+ hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes SM Watt, J Williamson, H Genevier, J Fawcett, DL Simmons, A Hatzfeld, ... | 199 | 1993 |
Heparan sulfate-protein interactions: therapeutic potential through structure-function insights DR Coombe, WC Kett Cellular and Molecular Life Sciences CMLS 62, 410-424, 2005 | 196 | 2005 |
Protein–heparin interactions measured by BIAcore 2000 are affected by the method of heparin immobilization RIW Osmond, WC Kett, SE Skett, DR Coombe Analytical biochemistry 310 (2), 199-207, 2002 | 166 | 2002 |
Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate DR Coombe, SM Watt, CR Parish | 130 | 1994 |
Probing the interactions of phosphosulfomannans with angiogenic growth factors by surface plasmon resonance S Cochran, C Li, JK Fairweather, WC Kett, DR Coombe, V Ferro Journal of medicinal chemistry 46 (21), 4601-4608, 2003 | 122 | 2003 |
Kinetics of chemokine–glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs Y Tanino, DR Coombe, SE Gill, WC Kett, O Kajikawa, AEI Proudfoot, ... The Journal of Immunology 184 (5), 2677-2685, 2010 | 115 | 2010 |
Anti-HIV-1 activity of chemically modified heparins: correlation between binding to the V3 loop of gp120 and inhibition of cellular HIV-1 infection in vitro CC Rider, DR Coombe, HA Harrop, EF Hounsell, C Bauer, J Feeney, ... Biochemistry 33 (22), 6974-6980, 1994 | 108 | 1994 |
Platelet associated fibrinogen and ICAM-2 induce firm adhesion of neutrophils under flow conditions PHM Kuijper, HIG Torres, JWJ Lammers, JJ Sixma, L Koenderman, ... Thrombosis and haemostasis 80 (09), 443-448, 1998 | 104 | 1998 |
Self/non-self recognition in invertebrates DR Coombe, PL Ey, CR Jenkin The Quarterly Review of Biology 59 (3), 231-255, 1984 | 102 | 1984 |
Interleukin-5 binds to heparin/heparan sulfate. A model for an interaction with extracellular matrix RJ Lipscombe, AM Nakhoul, CJ Sanderson, DR Coombe Journal of leukocyte biology 63 (3), 342-350, 1998 | 101 | 1998 |
Interactions between skeletal muscle myoblasts and their extracellular matrix revealed by a serum free culture system V Chaturvedi, DE Dye, BF Kinnear, TH Van Kuppevelt, MD Grounds, ... PloS one 10 (6), e0127675, 2015 | 100 | 2015 |
Heparin mimetics: Their therapeutic potential S Mohamed, DR Coombe Pharmaceuticals 10 (4), 78, 2017 | 99 | 2017 |
Heparin specifically inhibits binding of V3 loop antibodies to HIV-1 gp120, an effect potentiated by CD4 binding HA Harrop, DR Coombe, CC Rider Aids 8 (2), 183-192, 1994 | 89 | 1994 |
Biological implications of glycosaminoglycan interactions with haemopoietic cytokines DR Coombe Immunology and cell biology 86 (7), 598-607, 2008 | 87 | 2008 |
Avidin is a heparin-binding protein. Affinity, specificity and structural analysis WC Kett, RIW Osmond, L Moe, SE Skett, BF Kinnear, DR Coombe Biochimica et Biophysica Acta (BBA)-General Subjects 1620 (1-3), 225-234, 2003 | 68 | 2003 |
The interaction of heparin tetrasaccharides with chemokine CCL5 is modulated by sulfation pattern and pH A Singh, WC Kett, IC Severin, I Agyekum, J Duan, IJ Amster, ... Journal of Biological Chemistry 290 (25), 15421-15436, 2015 | 63 | 2015 |
Heparanase: A challenging cancer drug target DR Coombe, NS Gandhi Frontiers in Oncology 9, 1316, 2019 | 61 | 2019 |