| FOXO signaling pathways as therapeutic targets in cancer M Farhan, H Wang, U Gaur, PJ Little, J Xu, W Zheng International journal of biological sciences 13 (7), 815, 2017 | 392 | 2017 |
| cAMP response element-binding protein (CREB): a possible signaling molecule link in the pathophysiology of schizophrenia H Wang, J Xu, P Lazarovici, R Quirion, W Zheng Frontiers in molecular neuroscience 11, 255, 2018 | 337 | 2018 |
| The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats C Wang, XM Yang, YY Zhuo, H Zhou, HB Lin, YF Cheng, JP Xu, ... International Journal of Neuropsychopharmacology 15 (6), 749-766, 2012 | 183 | 2012 |
| Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25–35 or Aβ1–40 peptide in rats YF Cheng, C Wang, HB Lin, YF Li, Y Huang, JP Xu, HT Zhang Psychopharmacology 212, 181-191, 2010 | 133 | 2010 |
| FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects H Guo, Y Cheng, C Wang, J Wu, Z Zou, B Niu, H Yu, H Wang, J Xu Neuropharmacology 116, 260-269, 2017 | 104 | 2017 |
| The nerve growth factor signaling and its potential as therapeutic target for glaucoma H Wang, R Wang, T Thrimawithana, PJ Little, J Xu, ZP Feng, W Zheng BioMed research international 2014, 2014 | 100 | 2014 |
| Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder LM Zhang, ZK Qiu, N Zhao, HX Chen, YQ Liu, JP Xu, YZ Zhang, RF Yang, ... International Journal of Neuropsychopharmacology 17 (10), 1659-1669, 2014 | 98 | 2014 |
| Involvement of cell adhesion molecules in polydatin protection of brain tissues from ischemia–reperfusion injury Y Cheng, HT Zhang, L Sun, S Guo, S Ouyang, Y Zhang, J Xu Brain research 1110 (1), 193-200, 2006 | 95 | 2006 |
| Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson’s disease Y Chen, D Zhang, Z Liao, B Wang, S Gong, C Wang, M Zhang, G Wang, ... Molecular neurodegeneration 10, 1-14, 2015 | 92 | 2015 |
| Antidepressant effect of the extracts from Fructus Akebiae D Zhou, H Jin, HB Lin, XM Yang, YF Cheng, FJ Deng, JP Xu Pharmacology Biochemistry and Behavior 94 (3), 488-495, 2010 | 82 | 2010 |
| Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway B Xu, Y Qin, D Li, N Cai, J Wu, L Jiang, L Jie, Z Zhou, J Xu, H Wang Redox biology 28, 101342, 2020 | 80 | 2020 |
| Donepezil improves learning and memory deficits in APP/PS1 mice by inhibition of microglial activation HB Guo, YF Cheng, JG Wu, CM Wang, HT Wang, C Zhang, ZK Qiu, JP Xu Neuroscience 290, 530-542, 2015 | 80 | 2015 |
| RNA Interference-Mediated Knockdown of Long-Form Phosphodiesterase-4D (PDE4D) Enzyme Reverses Amyloid-β 42-Induced Memory Deficits in Mice C Zhang, Y Cheng, H Wang, C Wang, SP Wilson, J Xu, HT Zhang Journal of Alzheimer's Disease 38 (2), 269-280, 2014 | 80 | 2014 |
| Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer’s disease HB Lin, XM Yang, TJ Li, YF Cheng, HT Zhang, JP Xu Psychopharmacology 204, 705-714, 2009 | 71 | 2009 |
| Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats LX Li, YF Cheng, HB Lin, C Wang, JP Xu, HT Zhang Metabolic brain disease 26, 37-47, 2011 | 66 | 2011 |
| Repeated administration of AC-5216, a ligand for the 18 kDa translocator protein, improves behavioral deficits in a mouse model of post-traumatic stress disorder ZK Qiu, LM Zhang, N Zhao, HX Chen, YZ Zhang, YQ Liu, TY Mi, WW Zhou, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 45, 40-46, 2013 | 65 | 2013 |
| Inhibition of phosphodiesterase 4 by FCPR16 protects SH-SY5Y cells against MPP+-induced decline of mitochondrial membrane potential and oxidative stress J Zhong, H Yu, C Huang, Q Zhong, Y Chen, J Xie, Z Zhou, J Xu, H Wang Redox biology 16, 47-58, 2018 | 63 | 2018 |
| Antidepressant-like effects of 071031B, a novel serotonin and norepinephrine reuptake inhibitor R Xue, ZL Jin, HX Chen, L Yuan, XH He, YP Zhang, YG Meng, JP Xu, ... European Neuropsychopharmacology 23 (7), 728-741, 2013 | 62 | 2013 |
| Forkhead box O transcription factors as possible mediators in the development of major depression H Wang, R Quirion, PJ Little, Y Cheng, ZP Feng, HS Sun, J Xu, W Zheng Neuropharmacology 99, 527-537, 2015 | 57 | 2015 |
| Translocator protein 18 kDa (TSPO) deficiency inhibits microglial activation and impairs mitochondrial function R Yao, R Pan, C Shang, X Li, J Cheng, J Xu, Y Li Frontiers in pharmacology 11, 986, 2020 | 56 | 2020 |
Zheng WenHuaFaculty of Health Sciences, University of MacauVerified email at umac.mo
