| Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments L Somsak, V Nagy, Z Hadady, T Docsa, P Gergely Current pharmaceutical design 9 (15), 1177-1189, 2003 | 251 | 2003 |
| Synthesis of and a Comparative Study on the Inhibition of Muscle and Liver Glycogen Phosphorylases by Epimeric Pairs of d-Gluco- and d-Xylopyranosylidene-spiro-(thio)hydantoins … L Somsák, L Kovács, M Tóth, E Ősz, L Szilágyi, Z Györgydeák, Z Dinya, ... Journal of medicinal chemistry 44 (17), 2843-2848, 2001 | 183 | 2001 |
| Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin E Ősz, L Somsák, L Szilágyi, L Kovács, T Docsa, B Tóth, P Gergely Bioorganic & medicinal chemistry letters 9 (10), 1385-1390, 1999 | 123 | 1999 |
| Kinetic and crystallographic studies on 2‐(β‐D‐glucopyranosyl)‐5‐methyl‐1, 3, 4‐oxadiazole,‐benzothiazole, and‐benzimidazole, inhibitors of muscle glycogen phosphorylase b … ED Chrysina, MN Kosmopoulou, C Tiraidis, R Kardakaris, N Bischler, ... Protein science 14 (4), 873-888, 2005 | 108 | 2005 |
| Synthesis of 1-(D-glucopyranosyl)-1, 2, 3-triazoles and their evaluation as glycogen phosphorylase inhibitors É Bokor, T Docsa, P Gergely, L Somsák Bioorganic & medicinal chemistry 18 (3), 1171-1180, 2010 | 101 | 2010 |
| Binding of N‐acetyl‐N ′‐β‐d‐glucopyranosyl urea and N‐benzoyl‐N ′‐β‐d‐glucopyranosyl urea to glycogen phosphorylase b Kinetic and … NG Oikonomakos, M Kosmopoulou, SE Zographos, DD Leonidas, ... European journal of biochemistry 269 (6), 1684-1696, 2002 | 97 | 2002 |
| Synthesis and structure–activity relationships of C-glycosylated oxadiazoles as inhibitors of glycogen phosphorylase M Tóth, S Kun, É Bokor, M Benltifa, G Tallec, S Vidal, T Docsa, P Gergely, ... Bioorganic & medicinal chemistry 17 (13), 4773-4785, 2009 | 90 | 2009 |
| Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition D Goyard, B Kónya, AS Chajistamatiou, ED Chrysina, J Leroy, S Balzarin, ... European Journal of Medicinal Chemistry 108, 444-454, 2016 | 88 | 2016 |
| Synthesis of N-(β-D-glucopyranosyl)-and N-(2-acetamido-2-deoxy-β-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase Z Györgydeák, Z Hadady, N Felföldi, A Krakomperger, V Nagy, M Tóth, ... Bioorganic & medicinal chemistry 12 (18), 4861-4870, 2004 | 88 | 2004 |
| Kinetic and crystallographic studies of glucopyranosylidene spirothiohydantoin binding to glycogen phosphorylase b NG Oikonomakos, VT Skamnaki, E Ösz, L Szilágyi, L Somsák, T Docsa, ... Bioorganic & medicinal chemistry 10 (2), 261-268, 2002 | 73 | 2002 |
| Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats T Docsa, K Czifrák, C Hüse, L Somsák, P Gergely Molecular Medicine Reports 4 (3), 477-481, 2011 | 71 | 2011 |
| Synthesis of variously coupled conjugates of D-glucose, 1, 3, 4-oxadiazole, and 1, 2, 3-triazole for inhibition of glycogen phosphorylase S Kun, GZ Nagy, M Tóth, L Czecze, AN Van Nhien, T Docsa, P Gergely, ... Carbohydrate research 346 (12), 1427-1438, 2011 | 68 | 2011 |
| Glycogen phosphorylase inhibitor N-(3, 5-dimethyl-benzoyl)-N’-(β-D-glucopyranosyl) urea improves glucose tolerance under normoglycemic and diabetic conditions and rearranges … L Nagy, T Docsa, M Szanto, A Brunyanszki, C Hegedűs, J Marton, ... PloS one 8 (7), e69420, 2013 | 64 | 2013 |
| New synthesis of 3-(β-D-glucopyranosyl)-5-substituted-1, 2, 4-triazoles, nanomolar inhibitors of glycogen phosphorylase S Kun, É Bokor, G Varga, B Szőcs, A Páhi, K Czifrák, M Tóth, L Juhász, ... European Journal of Medicinal Chemistry 76, 567-579, 2014 | 59 | 2014 |
| C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase E Bokor, T Docsa, P Gergely, L Somsák ACS Medicinal Chemistry Letters 4 (7), 612-615, 2013 | 59 | 2013 |
| Glucose-based spiro-heterocycles as potent inhibitors of glycogen phosphorylase V Nagy, M Benltifa, S Vidal, E Berzsényi, C Teilhet, K Czifrák, G Batta, ... Bioorganic & medicinal chemistry 17 (15), 5696-5707, 2009 | 58 | 2009 |
| Gram-scale synthesis of a glucopyranosylidene-spiro-thiohydantoin and its effect on hepatic glycogen metabolism studied in vitro and in vivo L Somsák, V Nagy, T Docsa, B Tóth, P Gergely Tetrahedron: Asymmetry 11 (2), 405-408, 2000 | 56 | 2000 |
| Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver … AL Kantsadi, É Bokor, S Kun, GA Stravodimos, DSM Chatzileontiadou, ... European Journal of Medicinal Chemistry 123, 737-745, 2016 | 51 | 2016 |
| In Search of Glycogen Phosphorylase Inhibitors: 5‐Substituted 3‐C‐Glucopyranosyl‐1, 2, 4‐oxadiazoles from β‐D‐Glucopyranosyl Cyanides upon Cyclization of O‐Acylamidoxime … M Benltifa, S Vidal, B Fenet, M Msaddek, PG Goekjian, JP Praly, ... European journal of organic chemistry 2006 (18), 4242-4256, 2006 | 48 | 2006 |
| Glycogen phosphorylase inhibition improves beta cell function L Nagy, J Márton, A Vida, G Kis, É Bokor, S Kun, M Gönczi, T Docsa, ... British journal of pharmacology 175 (2), 301-319, 2018 | 46 | 2018 |
Pál GergelyProfessor of Medical Chemistry, University of DebrecenVerified email at unideb.hu
