| PD-1 and its ligands in tolerance and immunity ME Keir, MJ Butte, GJ Freeman, AH Sharpe Annu. Rev. Immunol. 26, 677-704, 2008 | 6125 | 2008 |
| Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses MJ Butte, ME Keir, TB Phamduy, AH Sharpe, GJ Freeman Immunity 27 (1), 111-122, 2007 | 2096 | 2007 |
| Tissue expression of PD-L1 mediates peripheral T cell tolerance ME Keir, SC Liang, I Guleria, YE Latchman, A Qipo, LA Albacker, ... The Journal of experimental medicine 203 (4), 883-895, 2006 | 1439 | 2006 |
| PD-1 and its ligands in T-cell immunity ME Keir, LM Francisco, AH Sharpe Current opinion in immunology 19 (3), 309-314, 2007 | 535 | 2007 |
| Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial S Vermeire, S O'Byrne, M Keir, M Williams, TT Lu, JC Mansfield, CA Lamb, ... The Lancet 384 (9940), 309-318, 2014 | 500 | 2014 |
| PD-1 regulates self-reactive CD8+ T cell responses to antigen in lymph nodes and tissues ME Keir, GJ Freeman, AH Sharpe The Journal of Immunology 179 (8), 5064-5070, 2007 | 306 | 2007 |
| Endothelial Programmed Death-1 Ligand 1 (PD-L1) Regulates CD8+ T-Cell–Mediated Injury in the Heart N Grabie, I Gotsman, R DaCosta, H Pang, G Stavrakis, MJ Butte, ME Keir, ... Circulation 116 (18), 2062-2071, 2007 | 284 | 2007 |
| The role of IL-22 in intestinal health and disease ME Keir, T Yi, TT Lu, N Ghilardi Journal of Experimental Medicine 217 (3), 2020 | 281 | 2020 |
| The programmed death-1 ligand 1: B7-1 pathway restrains diabetogenic effector T cells in vivo AM Paterson, KE Brown, ME Keir, VK Vanguri, LV Riella, A Chandraker, ... The Journal of Immunology 187 (3), 1097-1105, 2011 | 238 | 2011 |
| Programmed death-1 (PD-1): PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes ME Keir, YE Latchman, GJ Freeman, AH Sharpe The Journal of Immunology 175 (11), 7372-7379, 2005 | 203 | 2005 |
| The B7/CD28 costimulatory family in autoimmunity ME Keir, AH Sharpe Immunological reviews 204 (1), 128-143, 2005 | 201 | 2005 |
| A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis PJ Rutgeerts, RN Fedorak, DW Hommes, A Sturm, DC Baumgart, ... Gut 62 (8), 1122-1130, 2013 | 172 | 2013 |
| Association between response to etrolizumab and expression of integrin αE and granzyme A in colon biopsies of patients with ulcerative colitis GW Tew, JA Hackney, D Gibbons, CA Lamb, D Luca, JG Egen, L Diehl, ... Gastroenterology 150 (2), 477-487. e9, 2016 | 162 | 2016 |
| PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice SN Mueller, VK Vanguri, SJ Ha, EE West, ME Keir, JN Glickman, ... The Journal of clinical investigation 120 (7), 2508-2515, 2010 | 159 | 2010 |
| Function of CSF1 and IL34 in macrophage homeostasis, inflammation, and cancer WY Lin, D Xu, CD Austin, P Caplazi, K Senger, Y Sun, S Jeet, J Young, ... Frontiers in immunology 10, 2019, 2019 | 147 | 2019 |
| Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC JF Colombel, ME Keir, A Scherl, R Zhao, G de Hertogh, WA Faubion, ... Gut 66 (12), 2063-2068, 2017 | 131 | 2017 |
| EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) study identifies fecal calprotectin, serum MMP9, and serum IL-22 as a novel combination of biomarkers for Crohn's … WA Faubion Jr, JG Fletcher, S O'byrne, BG Feagan, WJ De Villiers, ... Official journal of the American College of Gastroenterology| ACG 108 (12 …, 2013 | 119 | 2013 |
| Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling M Samie, J Lim, E Verschueren, JM Baughman, I Peng, A Wong, Y Kwon, ... Nature immunology 19 (3), 246-254, 2018 | 105 | 2018 |
| IFN-α secretion by type 2 predendritic cells up-regulates MHC class I in the HIV-1-infected thymus ME Keir, CA Stoddart, V Linquist-Stepps, ME Moreno, JM McCune The Journal of Immunology 168 (1), 325-331, 2002 | 104 | 2002 |
| Programmed death 1 ligand (PD-L) 1 and PD-L2 limit autoimmune kidney disease: distinct roles J Menke, JA Lucas, GC Zeller, ME Keir, XR Huang, N Tsuboi, ... The Journal of Immunology 179 (11), 7466-7477, 2007 | 102 | 2007 |
