Diane P. Genereux
Diane P. Genereux
Broad Institute of Harvard and MIT
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Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates
J Damas, GM Hughes, KC Keough, CA Painter, NS Persky, M Corbo, ...
Proceedings of the National Academy of Sciences 117 (36), 22311-22322, 2020
Progressive Cactus is a multiple-genome aligner for the thousand-genome era
J Armstrong, G Hickey, M Diekhans, IT Fiddes, AM Novak, A Deran, ...
Nature 587 (7833), 246-251, 2020
A comparative genomics multitool for scientific discovery and conservation
Nature 587 (7833), 240-245, 2020
Errors in the bisulfite conversion of DNA: modulating inappropriate-and failed-conversion frequencies
DP Genereux, WC Johnson, AF Burden, R Stöger, CD Laird
Nucleic acids research 36 (22), e150-e150, 2008
Transient exposure to low levels of insecticide affects metabolic networks of honeybee larvae
K Derecka, MJ Blythe, S Malla, DP Genereux, A Guffanti, P Pavan, ...
PloS one 8 (7), e68191, 2013
Ancestry-inclusive dog genomics challenges popular breed stereotypes
K Morrill, J Hekman, X Li, J McClure, B Logan, L Goodman, M Gao, ...
Science 376 (6592), eabk0639, 2022
A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns
DP Genereux, BE Miner, CT Bergstrom, CD Laird
Proceedings of the National Academy of Sciences 102 (16), 5802-5807, 2005
Evolutionary constraint and innovation across hundreds of placental mammals
MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ...
Science 380 (6643), eabn3943, 2023
Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder
HJ Noh, R Tang, J Flannick, C O’Dushlaine, R Swofford, D Howrigan, ...
Nature communications 8 (1), 774, 2017
Much ado about bacteria-to-vertebrate lateral gene transfer
DP Genereux, JM Logsdon
TRENDS in Genetics 19 (4), 191-195, 2003
A genomic timescale for placental mammal evolution
NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ...
Science 380 (6643), eabl8189, 2023
Integrating gene annotation with orthology inference at scale
BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ...
Science 380 (6643), eabn3107, 2023
Evolution of the ancestral mammalian karyotype and syntenic regions
J Damas, M Corbo, J Kim, J Turner-Maier, M Farré, DM Larkin, OA Ryder, ...
Proceedings of the National Academy of Sciences 119 (40), e2209139119, 2022
Leveraging base-pair mammalian constraint to understand genetic variation and human disease
PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ...
Science 380 (6643), eabn2937, 2023
Testing the FMR1 promoter for mosaicism in DNA methylation among CpG sites, strands, and cells in FMR1-expressing males with fragile X syndrome
R Stöger, DP Genereux, RJ Hagerman, PJ Hagerman, F Tassone, ...
PLoS One 6 (8), e23648, 2011
Statistical inference of transmission fidelity of DNA methylation patterns over somatic cell divisions in mammals
AQ Fu, DP Genereux, R Stöger, CD Laird, M Stephens
The annals of applied statistics 4 (2), 871, 2010
Three-dimensional genome rewiring in loci with human accelerated regions
KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ...
Science 380 (6643), eabm1696, 2023
Analysis of the human mucosal response to cholera reveals sustained activation of innate immune signaling pathways
DL Bourque, TR Bhuiyan, DP Genereux, R Rashu, CN Ellis, F Chowdhury, ...
Infection and immunity 86 (2), 10.1128/iai. 00594-17, 2018
Insights into mammalian TE diversity through the curation of 248 genome assemblies
AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ...
Science 380 (6643), eabn1430, 2023
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites
G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ...
Science 380 (6643), eabn7930, 2023
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