Berta Sanchez-Laorden
Berta Sanchez-Laorden
CSIC Scientist, Instituto de Neurociencias CSIC-UMH
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Melanocortin‐1 receptor structure and functional regulation
JC García‐Borrón, BL Sánchez‐Laorden, C Jiménez‐Cervantes
Pigment cell research 18 (6), 393-410, 2005
Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease.
MT Grande, B Sánchez-Laorden, C López-Blau, CA De Frutos, A Boutet, ...
Nat Med 21 (9), 989-97, 2015
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma
MR Girotti, M Pedersen, B Sanchez-Laorden, A Viros, S Turajlic, ...
Cancer discovery 3 (2), 158-167, 2013
Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A
I Arozarena, B Sanchez-Laorden, L Packer, C Hidalgo-Carcedo, ...
Cancer cell 19 (1), 45-57, 2011
Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53
A Viros, B Sanchez-Laorden, M Pedersen, SJ Furney, J Rae, K Hogan, ...
Nature 511 (7510), 478-482, 2014
Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma
MR Girotti, F Lopes, N Preece, D Niculescu-Duvaz, A Zambon, L Davies, ...
Cancer cell 27 (1), 85-96, 2015
The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα
MP Smith, B Sanchez-Laorden, K O'Brien, H Brunton, J Ferguson, ...
Cancer discovery 4 (10), 1214-1229, 2014
Diverse matrix metalloproteinase functions regulate cancer amoeboid migration
JL Orgaz, P Pandya, R Dalmeida, P Karagiannis, B Sanchez-Laorden, ...
Nature communications 5 (1), 1-13, 2014
BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling
B Sanchez-Laorden, A Viros, MR Girotti, M Pedersen, G Saturno, ...
Science signaling 7 (318), ra30-ra30, 2014
Dimerization of the human melanocortin 1 receptor: functional consequences and dominant-negative effects
BL Sánchez-Laorden, J Sánchez-Más, E Martínez-Alonso, ...
Journal of investigative dermatology 126 (1), 172-181, 2006
Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer
BL Sánchez-Laorden, C Jiménez-Cervantes, JC García-Borrón
Journal of Biological Chemistry 282 (5), 3241-3251, 2007
Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady‐state retention of mutant forms in the proximal golgi
BL Sánchez‐Laorden, C Herraiz, JC Valencia, VJ Hearing, ...
Journal of cellular physiology 220 (3), 640-654, 2009
The melanocortin-1 receptor carboxyl terminal pentapeptide is essential for MC1R function and expression on the cell surface
J Sanchez-Mas, BL Sanchez-Laorden, LA Guillo, C Jimenez-Cervantes, ...
Peptides 26 (10), 1848-1857, 2005
Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes
M Pedersen, HVN Küsters-Vandevelde, A Viros, PJTA Groenen, ...
Cancer discovery 3 (4), 458-469, 2013
Mechanism of dimerization of the human melanocortin 1 receptor
PT Zanna, BL Sánchez-Laorden, AB Pérez-Oliva, MC Turpín, C Herraiz, ...
Biochemical and biophysical research communications 368 (2), 211-216, 2008
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma. Cancer Discov. 2013; 3: 158–167. doi: 10.1158/2159-8290
MR Girotti, M Pedersen, B Sanchez-Laorden, A Viros, S Turajlic, ...
CD-12-0386.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
Mind the IQGAP
B Sanchez-Laorden, A Viros, R Marais
Cancer cell 23 (6), 715-717, 2013
Ultraviolet radiation–induced DNA damage is prognostic for outcome in melanoma
LD Trucco, PA Mundra, K Hogan, P Garcia-Martinez, A Viros, AK Mandal, ...
Nature medicine 25 (2), 221-224, 2019
Subcellular localization of antizyme inhibitor 2 in mammalian cells: Influence of intrinsic sequences and interaction with antizymes
AJ López‐Contreras, BL Sánchez‐Laorden, B Ramos‐Molina, ...
Journal of cellular biochemistry 107 (4), 732-740, 2009
Variant amino acids in different domains of the human melanocortin 1 receptor impair cell surface expression.
BL Sanchez-Laorden, J Sanchez-Mas, MC Turpin, JC Garcia-Borron, ...
Cellular and molecular biology (Noisy-le-Grand, France) 52 (2), 39-46, 2006
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