| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13477* | 2021 |
| Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ... Cell 149 (3), 656-670, 2012 | 1958 | 2012 |
| Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function A Viale, P Pettazzoni, CA Lyssiotis, H Ying, N Sánchez, M Marchesini, ... Nature 514 (7524), 628-632, 2014 | 1172 | 2014 |
| Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer A Kapoor, W Yao, H Ying, S Hua, A Liewen, Q Wang, Y Zhong, CJ Wu, ... Cell 158 (1), 185-197, 2014 | 697 | 2014 |
| Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway A Insinga, S Monestiroli, S Ronzoni, V Gelmetti, F Marchesi, A Viale, ... Nature medicine 11 (1), 71-76, 2005 | 669 | 2005 |
| Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells A Viale, F De Franco, A Orleth, V Cambiaghi, V Giuliani, D Bossi, ... Nature 457 (7225), 51-56, 2009 | 383 | 2009 |
| Tumors and mitochondrial respiration: a neglected connection A Viale, D Corti, GF Draetta Cancer research 75 (18), 3687-3691, 2015 | 248 | 2015 |
| Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ... Nature 542 (7639), 119-123, 2017 | 247 | 2017 |
| DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions A Insinga, A Cicalese, M Faretta, B Gallo, L Albano, S Ronzoni, L Furia, ... Proceedings of the National Academy of Sciences 110 (10), 3931-3936, 2013 | 169 | 2013 |
| Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer W Yao, JL Rose, W Wang, S Seth, H Jiang, A Taguchi, J Liu, L Yan, ... Nature 568 (7752), 410-414, 2019 | 151 | 2019 |
| In vivo functional platform targeting patient-derived xenografts identifies WDR5-Myc association as a critical determinant of pancreatic cancer A Carugo, G Genovese, S Seth, L Nezi, JL Rose, D Bossi, A Cicalese, ... Cell reports 16 (1), 133-147, 2016 | 132 | 2016 |
| Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer G Genovese, A Carugo, J Tepper, FS Robinson, L Li, M Svelto, L Nezi, ... Nature 542 (7641), 362-366, 2017 | 122 | 2017 |
| Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis E Del Poggetto, IL Ho, C Balestrieri, EY Yen, S Zhang, F Citron, R Shah, ... Science 373 (6561), eabj0486, 2021 | 119 | 2021 |
| Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice W Piacibello, S Bruno, F Sanavio, S Droetto, M Gunetti, L Ailles, ... Blood, The Journal of the American Society of Hematology 100 (13), 4391-4400, 2002 | 117 | 2002 |
| Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome S Colla, DST Ong, Y Ogoti, M Marchesini, NA Mistry, K Clise-Dwyer, ... Cancer cell 27 (5), 644-657, 2015 | 116 | 2015 |
| Pre-existing functional heterogeneity of tumorigenic compartment as the origin of chemoresistance in pancreatic tumors S Seth, CY Li, IL Ho, D Corti, S Loponte, L Sapio, E Del Poggetto, EY Yen, ... Cell reports 26 (6), 1518-1532. e9, 2019 | 87 | 2019 |
| Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer P Pettazzoni, A Viale, P Shah, A Carugo, H Ying, H Wang, G Genovese, ... Cancer research 75 (6), 1091-1101, 2015 | 85 | 2015 |
| Gorham‐Stout syndrome: a monocyte‐mediated cytokine propelled disease S Colucci, G Taraboletti, L Primo, A Viale, C Roca, D Valdembri, M Geuna, ... Journal of Bone and Mineral Research 21 (2), 207-218, 2006 | 76 | 2006 |
| p53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors A Carugo, R Minelli, L Sapio, M Soeung, F Carbone, FS Robinson, ... Cancer cell 35 (2), 204-220. e9, 2019 | 71 | 2019 |
| NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model M Mallardo, A Caronno, G Pruneri, PR Raviele, A Viale, PG Pelicci, ... Leukemia 27 (11), 2248-2251, 2013 | 53 | 2013 |
