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| Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ... Cancer Cell 30 (6), 891-908, 2016 | 224 | 2016 |
| ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells NI Park, P Guilhamon, K Desai, RF McAdam, E Langille, M O’Connor, ... Cell Stem Cell 21 (2), 209-224. e7, 2017 | 216 | 2017 |
| Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2 P Guilhamon, M Eskandarpour, D Halai, GA Wilson, A Feber, ... Nature communications 4, 2166, 2013 | 182 | 2013 |
| Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity LM Richards, OKN Whitley, G MacLeod, FMG Cavalli, FJ Coutinho, ... Nature Cancer 2 (2), 157-173, 2021 | 177 | 2021 |
| Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer Cell 35 (5), 782-797. e8, 2019 | 175 | 2019 |
| Using high-density DNA methylation arrays to profile copy number alterations A Feber, P Guilhamon, M Lechner, T Fenton, GA Wilson, C Thirlwell, ... Genome Biol 15 (2), R30, 2014 | 153 | 2014 |
| Epigenetic switch-induced viral mimicry evasion in chemotherapy resistant breast cancer G Deblois, SAM Tonekaboni, G Grillo, C Martinez, YI Kao, F Tai, I Ettayebi, ... Cancer Discovery, 2020 | 101 | 2020 |
| oxBS-450K: A method for analysing hydroxymethylation using 450K BeadChips SK Stewart, TJ Morris, P Guilhamon, H Bulstrode, M Bachman, ... Methods 72, 9-15, 2015 | 101 | 2015 |
| Metabolic regulation of the epigenome drives lethal infantile ependymoma KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ... Cell 181 (6), 1329-1345. e24, 2020 | 90 | 2020 |
| PRMT5 inhibition disrupts splicing and stemness in glioblastoma P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ... Nature Communications 12 (1), 1-17, 2021 | 86 | 2021 |
| A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, ... Cancer Cell 36 (1), 51-67. e7, 2019 | 82 | 2019 |
| Single-cell chromatin accessibility profiling of glioblastoma identifies an Invasive cancer stem cell population associated with lower survival P Guilhamon, C Chesnelong, MM Kushida, A Nikolic, D Singhal, ... eLife 10, e64090, 2021 | 62 | 2021 |
| Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors P Mazrooei, KJ Kron, Y Zhu, S Zhou, G Grillo, T Mehdi, M Ahmed, ... Cancer Cell, 2019 | 55 | 2019 |
| Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour J Charlton, RD Williams, NJ Sebire, S Popov, G Vujanic, T Chagtai, ... Genome Medicine 7 (1), 1-11, 2015 | 55 | 2015 |
| High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma M Johnston, A Nikolic, N Ninkovic, P Guilhamon, F Cavalli, S Seaman, ... Genome research, gr. 246520.118, 2019 | 54 | 2019 |
| Mucosal Transcriptomics Implicates Under Expression of BRINP3 in the Pathogenesis of Ulcerative Colitis PJ Smith, AP Levine, J Dunne, P Guilhamon, M Turmaine, GW Sewell, ... Inflammatory bowel diseases 20 (10), 1802-1812, 2014 | 40 | 2014 |
| Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing DS Paul, P Guilhamon, A Karpathakis, LM Butcher, C Thirlwell, A Feber, ... Epigenetics 9 (5), 2014 | 37 | 2014 |
| Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma S Badodi, A Dubuc, X Zhang, G Rosser, MDC Jaeger, MM Kameda-Smith, ... Cell Reports 21 (10), 2772-2784, 2017 | 33 | 2017 |
| Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics P Guilhamon, LM Butcher, N Presneau, GA Wilson, A Feber, DS Paul, ... Genome Medicine 6 (12), 116, 2014 | 30 | 2014 |
Mathieu Lupien, Ph.D.Senior Scientist/Professor, Princess Margaret Cancer CentreDirección de correo verificada de uhnresearch.ca
