Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients M López-Lázaro, N Pastor, SS Azrak, MJ Ayuso, CA Austin, F Cortés Journal of natural products 68 (11), 1642-1645, 2005 | 237 | 2005 |
Roles of DNA topoisomerases in chromosome segregation and mitosis F Cortés, N Pastor, S Mateos, I Domınguez Mutation Research/Reviews in Mutation Research 543 (1), 59-66, 2003 | 112 | 2003 |
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions ML Orta, A Höglund, JM Calderón-Montaño, I Domínguez, ... Nucleic acids research 42 (14), 9108-9120, 2014 | 86 | 2014 |
The coffee constituent chlorogenic acid induces cellular DNA damage and formation of topoisomerase I–and II–DNA complexes in cells E Burgos-Moron, JM Calderón-Montaño, ML Orta, N Pastor, ... Journal of agricultural and food chemistry 60 (30), 7384-7391, 2012 | 84 | 2012 |
5-Aza-2′-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair ML Orta, JM Calderon-Montano, I Dominguez, N Pastor, E Burgos-Moron, ... Nucleic acids research 41 (11), 5827-5836, 2013 | 80 | 2013 |
Evaluation of Genotoxic effects of heavy metals and arsenic in wild nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from southwestern … R Baos, R Jovani, N Pastor, JL Tella, B Jiménez, G Gómez, MJ González, ... Environmental Toxicology and Chemistry: An International Journal 25 (10 …, 2006 | 77 | 2006 |
Assessment of genotoxic damage by the comet assay in white storks (Ciconia ciconia) after the Donana ecological disaster N Pastor, M López-Lázaro, JL Tella, R Baos, F Hiraldo, F Cortés Mutagenesis 16 (3), 219-223, 2001 | 72 | 2001 |
Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii M López-Lázaro, NP De La Peña, N Pastor, C Martín-Cordero, E Navarro, ... Planta medica 69 (08), 701-704, 2003 | 65 | 2003 |
RENEB intercomparison exercises analyzing micronuclei (Cytokinesis-block Micronucleus Assay) J Depuydt, A Baeyens, S Barnard, C Beinke, A Benedek, P Beukes, ... International journal of radiation biology 93 (1), 36-47, 2017 | 64 | 2017 |
Toward a comprehensive model for induced endoreduplication F Cortés, S Mateos, N Pastor, I Domínguez Life sciences 76 (2), 121-135, 2004 | 56 | 2004 |
DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193 N Hajji, N Pastor, S Mateos, I Domınguez, F Cortes Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 530 (1 …, 2003 | 54 | 2003 |
Induction of endoreduplication by topoisomerase II catalytic inhibitors F Cortés, N Pastor Mutagenesis 18 (2), 105-112, 2003 | 54 | 2003 |
A 4 year follow‐up analysis of genotoxic damage in birds of the Doñana area (south west Spain) in the wake of the 1998 mining waste spill N Pastor, R Baos, M López‐Lázaro, R Jovani, JL Tella, N Hajji, F Hiraldo, ... Mutagenesis 19 (1), 61-65, 2004 | 51 | 2004 |
Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor N Hajji, S Mateos, N Pastor, I Dominguez, F Cortes Mutation Research/Genetic Toxicology and Environmental Mutagenesis 583 (1 …, 2005 | 45 | 2005 |
Both bovine and rabbit lymphocytes conditioned with hydrogen peroxide show an adaptive response to radiation damage MJ Flores, J Pinero, T Ortiz, N Pastor, JC Mateos, F Cortes Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 372 (1 …, 1996 | 39 | 1996 |
Tea flavanols inhibit cell growth and DNA topoisomerase II activity and induce endoreduplication in cultured Chinese hamster cells K Neukam, N Pastor, F Cortes Mutation Research/Genetic Toxicology and Environmental Mutagenesis 654 (1), 8-12, 2008 | 37 | 2008 |
Bufalin influences the repair of X-ray-induced DNA breaks in Chinese hamster cells N Pastor, F Cortés DNA repair 2 (12), 1353-1360, 2003 | 33 | 2003 |
Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II G Cantero, N Pastor, S Mateos, C Campanella, F Cortés Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 599 (1 …, 2006 | 31 | 2006 |
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I-and II-DNA complexes and cancer cell death JM Calderón-Montaño, E Burgos-Morón, ML Orta, N Pastor, CA Austin, ... Toxicology Letters 222 (1), 64-71, 2013 | 29 | 2013 |
The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication N Pastor, I Domínguez, ML Orta, C Campanella, S Mateos, F Cortés Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 738, 45-51, 2012 | 28 | 2012 |