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Javier García-Cárceles
Javier García-Cárceles
Professor of Chemistry at the Spanish Customs Laboratory
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New synthetic inhibitors of fatty acid synthase with anticancer activity
C Turrado, T Puig, J García-Cárceles, M Artola, B Benhamú, ...
Journal of medicinal chemistry 55 (11), 5013-5023, 2012
792012
Recent Methodologies That Exploit Oxidative Addition of C–N Bonds to Transition Metals
J Garcı́a-Cárceles, KA Bahou, JF Bower
ACS Catalysis 10 (21), 12738-12759, 2020
602020
A new serotonin 5-HT6 receptor antagonist with procognitive activity – Importance of a halogen bond interaction to stabilize the binding
JA González-Vera, RA Medina, M Martín-Fontecha, A Gonzalez, ...
Scientific reports 7 (1), 41293, 2017
472017
Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells
MJ Bueno, V Jimenez-Renard, S Samino, J Capellades, A Junza, ...
Nature communications 10 (1), 5011, 2019
462019
A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity
J Garcia-Carceles, JM Decara, H Vazquez-Villa, R Rodriguez, ...
Journal of Medicinal Chemistry 60 (23), 9575-9584, 2017
402017
Kinase inhibitors as underexplored antiviral agents
J García-Cárceles, E Caballero, C Gil, A Martínez
Journal of medicinal chemistry 65 (2), 935-954, 2021
342021
Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods
T Ginex, U Garaigorta, D Ramírez, V Castro, V Nozal, I Maestro, ...
Pharmaceuticals 14 (4), 332, 2021
262021
Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C–H Functionalization Cascades
BT Jones, J García-Cárceles, L Caiger, IR Hazelden, RJ Lewis, T Langer, ...
Journal of the American Chemical Society 143 (38), 15593-15598, 2021
222021
Discovery of V-0219: a small-molecule positive allosteric modulator of the glucagon-like peptide-1 receptor toward oral treatment for “diabesity”
JM Decara, H Vázquez-Villa, J Brea, M Alonso, RK Srivastava, L Orio, ...
Journal of medicinal chemistry 65 (7), 5449-5461, 2022
72022
2-(fluoromethoxy)-4′-(s-methanesulfonimidoyl)-1, 1′-biphenyl (UCM-1306), an orally bioavailable positive allosteric modulator of the human dopamine D1 receptor for Parkinson …
J García-Cárceles, H Vázquez-Villa, J Brea, ...
Journal of Medicinal Chemistry 65 (18), 12256-12272, 2022
52022
Novel Strategies Targeting G‐Protein‐Coupled Receptors: An Overview
J García‐Cárceles
eLS, 1-9, 2018
2018
A new serotonin 5-HT6 receptor antagonist with procognitive activity
JA González-Vera, RA Medina, M Martín-Fontecha, A Gonzalez, ...
2017
Allosteric modulators of serotonin and dopamine receptors: new drugs on GPCRs
JG Carceles
Universidad Complutense de Madrid, 2017
2017
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