Roberto Jun Arai
Roberto Jun Arai
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Thioredoxin-dependent redox regulation of p53-mediated p21 activation
M Ueno, H Masutani, RJ Arai, A Yamauchi, K Hirota, T Sakai, T Inamoto, ...
Journal of Biological Chemistry 274 (50), 35809-35815, 1999
Protein tyrosine phosphorylation and protein tyrosine nitration in redox signaling
HP Monteiro, RJ Arai, LR Travassos
Antioxidants & redox signaling 10 (5), 843-890, 2008
Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells
CJR Oliveira, F Schindler, AM Ventura, MS Morais, RJ Arai, V Debbas, ...
Free Radical Biology and Medicine 35 (4), 381-396, 2003
Nitric oxide induces thioredoxin-1 nuclear translocation: possible association with the p21Ras survival pathway
RJ Arai, H Masutani, J Yodoi, V Debbas, FR Laurindo, A Stern, ...
Biochemical and biophysical research communications 348 (4), 1254-1260, 2006
Thioredoxin-1 promotes survival in cells exposed to S-nitrosoglutathione: correlation with reduction of intracellular levels of nitrosothiols and up-regulation of the ERK1/2 …
RJ Arai, FT Ogata, WL Batista, H Masutani, J Yodoi, V Debbas, O Augusto, ...
Toxicology and applied pharmacology 233 (2), 227-237, 2008
S-nitrosoglutathione and endothelial nitric oxide synthase-derived nitric oxide regulate compartmentalized ras S-nitrosylation and stimulate cell proliferation
WL Batista, FT Ogata, MF Curcio, RB Miguel, RJ Arai, AL Matsuo, ...
Antioxidants & redox signaling 18 (3), 221-238, 2013
Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization
FT Ogata, WL Batista, A Sartori, TF Gesteira, H Masutani, RJ Arai, J Yodoi, ...
PLoS One 8 (12), e84588, 2013
The nitric oxide-sensitive p21Ras–ERK pathway mediates S-nitrosoglutathione-induced apoptosis
M Tsujita, WL Batista, FT Ogata, A Stern, HP Monteiro, RJ Arai
Biochemical and biophysical research communications 369 (4), 1001-1006, 2008
Regulation of p21Waf1 expression and TNFα biosynthesis by glutathione modulators in PMA induced-THP1 differentiation: Involvement of JNK and ERK pathways
V Debbas, RJ Arai, S Ferderbar, F Schindler, A Stern, HP Monteiro
Biochemical and biophysical research communications 363 (4), 965-970, 2007
Sample size calculation in oncology trials
GM Bariani, ACR de Celis Ferrari, M Precivale, R Arai, ED Saad, ...
American journal of clinical oncology 38 (6), 570-574, 2015
Building research capacity and clinical trials in developing countries
RJ Arai, MS Mano, G de Castro Jr, MDPE Diz, PMG Hoff
The Lancet Oncology 11 (8), 712-713, 2010
I Brazilian guideline for cardio-oncology from Sociedade Brasileira de Cardiologia
SB de Oncologia Clínica, ICF de Medicina, R Kalil Filho, LA Hajjar, ...
Arquivos brasileiros de cardiologia 96 (2 Suppl 1), 1-52, 2011
Tyrosine Phosphorylation in Nitric Oxide–Mediated Signaling Events
HP Monteiro, CJR Oliveira, MF Curcio, MS Moraes, RJ Arai
Methods in enzymology 396, 350-358, 2005
Metronomic chemotherapy in the neoadjuvant setting: results of two parallel feasibility trials (TraQme and TAME) in patients with HER2+ and HER2− locally advanced breast cancer
V Petry, DM Gagliato, AIC Leal, RJ Arai, E Longo, F Andrade, MD Ricci, ...
Brazilian Journal of Medical and Biological Research 48 (5), 479-485, 2015
Rare tumors research in emerging countries
MS Mano, RJ Arai, PMG Hoff
Rare tumors 2 (3), 142-143, 2010
Ethical responsibility of phase 0 trials
RJ Arai, PMG Hoff, G de Castro, A Stern
Clinical Cancer Research 15 (3), 1121-1121, 2009
Bringing a humanistic approach to cancer clinical trials
RJ Arai, ES Longo, MH Sponton, MDPE Diz
ecancermedicalscience 11, 2017
Serial review: role of reactive oxygen and nitrogen species (ROS/RNS) in lung injury and diseases
F Tao, B Gonzalez-Flecha, L Kobzik, PJ Lee, AMK Choi, MZ Dieter, ...
Free Radic. Biol. Med 35, 327-340, 2003
Serum levels of VEGF and MCSF in HER2+/HER2-breast cancer patients with metronomic neoadjuvant chemotherapy
RJ Arai, V Petry, PM Hoff, MS Mano
Biomarker research 6 (1), 1-6, 2018
Academic health centers: integration of clinical research with healthcare and education. Comments on a workshop
RJ Arai, IL Noronha, JC Nicolau, C Schmidt, GM de Albuquerque, ...
Clinics 73, 2018
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