Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors R Linge, L Jiménez-Sánchez, L Campa, F Pilar-Cuéllar, R Vidal, A Pazos, ... Neuropharmacology 103, 16-26, 2016 | 298 | 2016 |
Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome C Martínez-Cué, P Martínez, N Rueda, R Vidal, S García, V Vidal, ... Journal of Neuroscience 33 (9), 3953-3966, 2013 | 188 | 2013 |
Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes A Herrero, A Pinto, P Colón-Bolea, B Casar, M Jones, L Agudo-Ibáñez, ... Cancer cell 28 (2), 170-182, 2015 | 145 | 2015 |
Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome S García-Cerro, P Martínez, V Vidal, A Corrales, J Flórez, R Vidal, ... PloS one 9 (9), e106572, 2014 | 110 | 2014 |
Modulation of neuroplasticity pathways and antidepressant-like behavioural responses following the short-term (3 and 7 days) administration of the 5-HT4 receptor … J Pascual-Brazo, E Castro, Á Díaz, EM Valdizán, F Pilar-Cuéllar, R Vidal, ... International Journal of Neuropsychopharmacology 15 (5), 631-643, 2012 | 109 | 2012 |
Neural plasticity and proliferation in the generation of antidepressant effects: hippocampal implication F Pilar-Cuéllar, R Vidal, A Díaz, E Castro, S dos Anjos, J Pascual-Brazo, ... Neural plasticity 2013, 2013 | 105 | 2013 |
Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine1A receptor … S Mato, R Vidal, E Castro, Á Díaz, Á Pazos, EM Valdizán Molecular pharmacology 77 (3), 424-434, 2010 | 89 | 2010 |
Long‐term treatment with fluoxetine induces desensitization of 5‐HT4 receptor‐dependent signalling and functionality in rat brain R Vidal, EM Valdizán, R Mostany, A Pazos, E Castro Journal of neurochemistry 110 (3), 1120-1127, 2009 | 79 | 2009 |
New strategies in the development of antidepressants: towards the modulation of neuroplasticity pathways R Vidal, F Pilar-Cuéllar, S dos Anjos, R Linge, B Treceno, V Ines Vargas, ... Current pharmaceutical design 17 (5), 521-533, 2011 | 70 | 2011 |
Subchronic treatment with fluoxetine and ketanserin increases hippocampal brain‐derived neurotrophic factor, β‐catenin and antidepressant‐like effects F Pilar‐Cuéllar, R Vidal, A Pazos British journal of pharmacology 165 (4b), 1046-1057, 2012 | 69 | 2012 |
The absence of 5-HT4 receptors modulates depression-and anxiety-like responses and influences the response of fluoxetine in olfactory bulbectomised mice: adaptive changes in … J Amigó, A Díaz, F Pilar-Cuéllar, R Vidal, A Martín, V Compan, A Pazos, ... Neuropharmacology 111, 47-58, 2016 | 65 | 2016 |
Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration A Ferrés-Coy, M Galofré, F Pilar-Cuéllar, R Vidal, V Paz, E Ruiz-Bronchal, ... Molecular psychiatry 21 (3), 328-338, 2016 | 63 | 2016 |
RNAi-mediated serotonin transporter suppression rapidly increases serotonergic neurotransmission and hippocampal neurogenesis A Ferrés-Coy, F Pilar-Cuellar, R Vidal, V Paz, M Masana, R Cortés, ... Translational psychiatry 3 (1), e211-e211, 2013 | 62 | 2013 |
Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of D own syndrome A Corrales, R Vidal, S García, V Vidal, P Martínez, E García, J Flórez, ... Journal of pineal research 56 (1), 51-61, 2014 | 58 | 2014 |
Signaling pathways involved in antidepressant-induced cell proliferation and synaptic plasticity F Pilar-Cuellar, R Vidal, A Diaz, E Castro, S dos Anjos, V Vargas, ... Current Pharmaceutical Design 20 (23), 3776-3794, 2014 | 39 | 2014 |
Serotonin 5-HT4 receptors: A new strategy for developing fast acting antidepressants? R Vidal, E Castro, F Pilar-Cuellar, J Pascual-Brazo, A Diaz, M Luisa Rojo, ... Current pharmaceutical design 20 (23), 3751-3762, 2014 | 36 | 2014 |
Reduced signal transduction by 5‐HT4 receptors after long‐term venlafaxine treatment in rats R Vidal, EM Valdizán, MT Vilaró, A Pazos, E Castro British journal of pharmacology 161 (3), 695-706, 2010 | 35 | 2010 |
Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens P Gimenez-Gomez, M Perez-Hernandez, MD Gutiérrez-López, R Vidal, ... Neuropharmacology 135, 581-591, 2018 | 34 | 2018 |
3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) produces edema due to BBB disruption induced by MMP-9 activation in rat hippocampus M Pérez-Hernández, ME Fernández-Valle, A Rubio-Araiz, R Vidal, ... Neuropharmacology 118, 157-166, 2017 | 33 | 2017 |
Targeting β-catenin in GLAST-expressing cells: impact on anxiety and depression-related behavior and hippocampal proliferation R Vidal, E Garro-Martínez, Á Díaz, E Castro, E Florensa-Zanuy, ... Molecular Neurobiology 56, 553-566, 2019 | 32 | 2019 |