| Phenotype molding of stromal cells in the lung tumor microenvironment D Lambrechts, E Wauters, B Boeckx, S Aibar, D Nittner, O Burton, ... Nature medicine 24 (8), 1277-1289, 2018 | 1235 | 2018 |
| Tumour hypoxia causes DNA hypermethylation by reducing TET activity B Thienpont, J Steinbacher, H Zhao, F D’Anna, A Kuchnio, A Ploumakis, ... Nature 537 (7618), 63-68, 2016 | 579 | 2016 |
| Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ... Cancer cell 30 (6), 968-985, 2016 | 551 | 2016 |
| Self-maintaining gut macrophages are essential for intestinal homeostasis S De Schepper, S Verheijden, J Aguilera-Lizarraga, MF Viola, ... Cell 175 (2), 400-415. e13, 2018 | 464 | 2018 |
| A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling J Qian, S Olbrecht, B Boeckx, H Vos, D Laoui, E Etlioglu, E Wauters, ... Cell research 30 (9), 745-762, 2020 | 429 | 2020 |
| Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer HO Lee, Y Hong, HE Etlioglu, YB Cho, V Pomella, B Van den Bosch, ... Nature genetics 52 (6), 594-603, 2020 | 421 | 2020 |
| p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity C Adriaens, L Standaert, J Barra, M Latil, A Verfaillie, P Kalev, B Boeckx, ... Nature medicine 22 (8), 861-868, 2016 | 413 | 2016 |
| A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer A Bassez, H Vos, L Van Dyck, G Floris, I Arijs, C Desmedt, B Boeckx, ... Nature medicine 27 (5), 820-832, 2021 | 367 | 2021 |
| Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals MS Levine, B Bakker, B Boeckx, J Moyett, J Lu, B Vitre, DC Spierings, ... Developmental cell 40 (3), 313-322. e5, 2017 | 355 | 2017 |
| Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 351 | 2017 |
| An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ... Cancer cell 37 (1), 21-36. e13, 2020 | 332 | 2020 |
| Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening M Boretto, N Maenhoudt, X Luo, A Hennes, B Boeckx, B Bui, R Heremans, ... Nature cell biology 21 (8), 1041-1051, 2019 | 325 | 2019 |
| Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages E Wauters, P Van Mol, AD Garg, S Jansen, Y Van Herck, L Vanderbeke, ... Cell research 31 (3), 272-290, 2021 | 272 | 2021 |
| Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity L Vanderbeke, P Van Mol, Y Van Herck, F De Smet, S Humblet-Baron, ... Nature communications 12 (1), 4117, 2021 | 200 | 2021 |
| Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis C Lange, M Turrero Garcia, I Decimo, F Bifari, G Eelen, A Quaegebeur, ... The EMBO journal 35 (9), 924-941, 2016 | 197 | 2016 |
| Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma D Nassar, M Latil, B Boeckx, D Lambrechts, C Blanpain Nature medicine 21 (8), 946-954, 2015 | 181 | 2015 |
| Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis Ö Serçin, JC Larsimont, AE Karambelas, V Marthiens, V Moers, B Boeckx, ... Nature cell biology 18 (1), 100-110, 2016 | 177 | 2016 |
| Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2 J Baggen, L Persoons, E Vanstreels, S Jansen, D Van Looveren, ... Nature Genetics 53 (4), 435-444, 2021 | 169 | 2021 |
| Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching L De Smedt, S Palmans, D Andel, O Govaere, B Boeckx, D Smeets, ... British journal of cancer 116 (1), 58-65, 2017 | 159 | 2017 |
| Developing organoids from ovarian cancer as experimental and preclinical models N Maenhoudt, C Defraye, M Boretto, Z Jan, R Heremans, B Boeckx, ... Stem Cell Reports 14 (4), 717-729, 2020 | 128 | 2020 |
