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Amit Mahindra
Amit Mahindra
Sygnature Discovery
Dirección de correo verificada de sygnaturediscovery.com
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Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target
MM Alam, A Sanchez-Azqueta, O Janha, EL Flannery, A Mahindra, ...
Science 365 (6456), eaau1682, 2019
642019
Palladium-Catalyzed Regioselective C-5 Arylation of Protected l-Histidine: Microwave-Assisted C–H Activation Adjacent to Donor Arm
A Mahindra, N Bagra, R Jain
The Journal of Organic Chemistry 78 (21), 10954-10959, 2013
502013
Rapid microwave-assisted solution-phase peptide synthesis
A Mahindra, KK Sharma, R Jain
Tetrahedron Letters 53 (51), 6931-6935, 2012
412012
Discovery of Short Peptides Exhibiting High Potency against Cryptococcus neoformans
A Mahindra, N Bagra, N Wangoo, SI Khan, MR Jacob, R Jain
ACS medicinal chemistry letters 5 (4), 315-320, 2014
322014
Stapled ACE2 peptidomimetics designed to target the SARS‐CoV‐2 spike protein do not prevent virus internalization
DC Morgan, C Morris, A Mahindra, CM Blair, G Tejeda, I Herbert, ...
Peptide Science 113 (4), e24217, 2021
302021
Microwave-assisted solution phase peptide synthesis in neat water
A Mahindra, K Nooney, S Uraon, KK Sharma, R Jain
RSC advances 3 (37), 16810-16816, 2013
282013
Solvent-free peptide synthesis assisted by microwave irradiation: environmentally benign synthesis of bioactive peptides
A Mahindra, N Patel, N Bagra, R Jain
RSC advances 4 (6), 3065-3069, 2014
272014
Synthesis and antimicrobial activities of His (2-aryl)-Arg and Trp-His (2-aryl) classes of dipeptidomimetics
A Mahindra, KK Sharma, D Rathore, SI Khan, MR Jacob, R Jain
MedChemComm 5 (5), 671-676, 2014
242014
Regiospecific Direct C–H Arylation at the 2-Position of l-Histidine Using Arylboronic Acids
A Mahindra, R Jain
Synlett 23 (12), 1759-1764, 2012
212012
Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials
A Mahindra, O Janha, K Mapesa, A Sanchez-Azqueta, MM Alam, ...
Journal of medicinal chemistry 63 (17), 9300-9315, 2020
192020
Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus
GC Girt, A Mahindra, ZJH Al Jabri, MDS Croix, MR Oggioni, AG Jamieson
Chemical communications 54 (22), 2767-2770, 2018
172018
Regiocontrolled palladium-catalyzed and copper-mediated C–H bond functionalization of protected L-histidine
A Mahindra, R Jain
Organic & Biomolecular Chemistry 12 (23), 3792-3796, 2014
172014
Synthetically modified L-histidine-rich peptidomimetics exhibit potent activity against Cryptococcus neoformans
A Mahindra, N Bagra, N Wangoo, R Jain, SI Khan, MR Jacob, R Jain
Bioorganic & medicinal chemistry letters 24 (14), 3150-3154, 2014
162014
Synthesis of HDAC substrate peptidomimetic inhibitors using fmoc amino acids incorporating zinc-binding groups
A Mahindra, CJ Millard, I Black, LJ Archibald, JWR Schwabe, ...
Organic letters 21 (9), 3178-3182, 2019
152019
Antiplasmodial activity of short peptide-based compounds
A Mahindra, RP Gangwal, S Bansal, NE Goldfarb, BM Dunn, ...
RSC Advances 5 (29), 22674-22684, 2015
82015
Investigating the structure–activity relationship of 1, 2, 4-triazine G-protein-coupled receptor 84 (GPR84) antagonists
A Mahindra, L Jenkins, S Marsango, M Huggett, M Huggett, L Robinson, ...
Journal of medicinal chemistry 65 (16), 11270-11290, 2022
62022
Design, synthesis, and applications of ring‐functionalized histidines in peptide‐based medicinal chemistry and drug discovery
K Sharma, KK Sharma, A Mahindra, N Sehra, N Bagra, S Aaghaz, ...
Medicinal Research Reviews 43 (4), 775-828, 2023
42023
Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction
A Mahindra, G Tejeda, M Rossi, O Janha, I Herbert, C Morris, DC Morgan, ...
Plos one 16 (11), e0260283, 2021
12021
Fmoc protected (2s)-2-amino-8-[(1, 1-dimethylethoxy) amino]-8-oxo-octanoic acid,(s)-2-amino-8-oxononanoic acid and (s)-2-amino-8-oxodecanoic acid for peptide synthesis
A Jamieson, A MAHINDRA, I BLACK
2019
Development of potent and selective PfCLK3 inhibitors based on GSK-TCMDC151 as a new class of antimalarials
A Mahindra, O Janha, K Mapesa, A Sanchez-Azqueta, MM Alam, A Tobin, ...
2019
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