Bruno Manta

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Gerardo Ferrer-SuetaAssociate Professor, Fisicoquímica Biológica, Facultad de Ciencias,Universidad de la RepúblicaVerified email at fmed.edu.uy
Marcelo CominiPrincipal Investigator, Institut Pasteur de Montevideo, UruguayVerified email at pasteur.edu.uy
Ana DenicolaProfessor of Physical Biochemistry, University of the Republic, UruguayVerified email at fcien.edu.uy
Bernard KnoopsUniversité catholique de LouvainVerified email at uclouvain.be
Massimo BellandaAssistant Professor, Department of Chemical Sciences, University of PadovaVerified email at unipd.it
Vadim GladyshevProfessor of Medicine, Brigham and Women's Hospital, Harvard Medical SchoolVerified email at rics.bwh.harvard.edu
Mattia SturleseDipartimento di Scienze del FarmacoVerified email at unipd.it
Horacio BottiAdjunct Profesor, Integrative Biophysics Laboratory, Depto. de Biofísica, Facultad de MedicinaVerified email at pasteur.edu.uy
Mehmet BerkmenNew England BiolabsVerified email at neb.com
E. Laura CoitiñoProf. de Química Teórica&Computacional, Instituto de Quím. Biológica-Fac.Ciencias, UdelaRVerified email at fcien.edu.uy
Luis Eduardo Soares NettoPorfessor de Genética, Instituto de Biociencias, Universidade de São PauloVerified email at ib.usp.br
Gisele MonteiroProfessor Doutor Tecnologia Bioquímico-Farmacêutica, FCF,USPVerified email at usp.br
Marco MariottiRamón y Cajal Fellow, Group Leader @ Department of Genetics, Microbiology and StatisticsVerified email at ub.edu
Gustavo SalinasFacultad de Química, Universidad de la República - Institut Pasteur de MontevideoVerified email at fq.edu.uy
Magdalena GilInstitut PasteurVerified email at pasteur.fr
Carlos BatthyányInstitut Pasteur de MontevideoVerified email at pasteur.edu.uy
Toni GabaldonGroup Leader, Institute for Research in Biomedicine (IRB), Barcelona Supercomputing Centre (BSC)Verified email at crg.es
Roderic GuigoProfessor of Bioinformatics, Center for Genomic Regulation, Universitat Pompeu FabraVerified email at crg.cat
Didac SantesmassesTome BiosciencesVerified email at bwh.harvard.edu
Moreno LelliDepartment of Chemistry, Univeristy of FlorenceVerified email at unifi.it

Bruno Manta

Institut Pasteur Montevideo / Universidad de la Republica

Verified email at pasteur.edu.uy

Biochemistry Genetics Microbiology Biophysics Enzymes


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Factors affecting protein thiol reactivity and specificity in peroxide reduction G Ferrer-Sueta, B Manta, H Botti, R Radi, M Trujillo, A Denicola Chemical research in toxicology 24 (4), 434-450, 2011	328	2011
SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species X Tian, D Firsanov, Z Zhang, Y Cheng, L Luo, G Tombline, R Tan, ... Cell 177 (3), 622-638. e22, 2019	244	2019
The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2 B Manta, M Hugo, C Ortiz, G Ferrer-Sueta, M Trujillo, A Denicola Archives of biochemistry and biophysics 484 (2), 146-154, 2009	242	2009
Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation M Trujillo, A Clippe, B Manta, G Ferrer-Sueta, A Smeets, JP Declercq, ... Archives of biochemistry and biophysics 467 (1), 95-106, 2007	193	2007
Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids B Manta, M Comini, A Medeiros, M Hugo, M Trujillo, R Radi Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (5), 3199-3216, 2013	141	2013
Thiol and Sulfenic Acid Oxidation of AhpE, the One-Cysteine Peroxiredoxin from Mycobacterium tuberculosis: Kinetics, Acidity Constants, and Conformational … M Hugo, L Turell, B Manta, H Botti, G Monteiro, LES Netto, B Alvarez, ... Biochemistry 48 (40), 9416-9426, 2009	140	2009
Deconstructing the catalytic efficiency of peroxiredoxin-5 peroxidatic cysteine S Portillo-Ledesma, F Sardi, B Manta, MV Tourn, A Clippe, B Knoops, ... Biochemistry 53 (38), 6113-6125, 2014	90	2014
Regulated methionine oxidation by monooxygenases B Manta, VN Gladyshev Free Radical Biology and Medicine 109, 141-155, 2017	78	2017
Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection F Sardi, B Manta, S Portillo-Ledesma, B Knoops, MA Comini, ... Analytical Biochemistry 435 (1), 74-82, 2013	59	2013
Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase LM Randall, B Manta, M Hugo, M Gil, C Batthyàny, M Trujillo, LB Poole, ... Journal of Biological Chemistry 289 (22), 15536-15543, 2014	55	2014
Iron–sulfur cluster binding by mitochondrial monothiol glutaredoxin-1 of Trypanosoma brucei: molecular basis of iron–sulfur cluster coordination and relevance for parasite … B Manta, C Pavan, M Sturlese, A Medeiros, M Crispo, C Berndt, ... Antioxidants & redox signaling 19 (7), 665-682, 2013	48	2013
Disulfide Bond Formation in the Periplasm of Escherichia coli B Manta, D Boyd, M Berkmen EcoSal Plus 8 (2), 10.1128/ecosalplus. ESP-0012-2018, 2019	42	2019
Lokiarchaeota Marks the Transition between the Archaeal and Eukaryotic Selenocysteine Encoding Systems M Mariotti, AV Lobanov, B Manta, D Santesmasses, A Bofill, R Guigó, ... Molecular Biology and Evolution 33 (9), 2441-2453, 2016	42	2016
Polyamine-based thiols in trypanosomatids: evolution, protein structural adaptations, and biological functions B Manta, M Bonilla, L Fiestas, M Sturlese, G Salinas, M Bellanda, ... Antioxidants & Redox Signaling 28 (6), 463-486, 2018	33	2018
Fisiopatología de la enfermedad COVID-19 B Manta, AG Sarkisian, B García-Fontana, V Pereira-Prado Odontoestomatología 24 (39), 2022	31	2022
Tools to evaluate the conformation of protein products B Manta, G Obal, A Ricciardi, O Pritsch, A Denicola Biotechnology Journal 6 (6), 731-741, 2011	30	2011
MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII K Konstantinidis, VJ Bezzerides, L Lai, HM Isbell, AC Wei, Y Wu, ... The Journal of clinical investigation 130 (9), 4663-4678, 2020	28	2020
Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form L Randall, B Manta, KJ Nelson, J Santos, LB Poole, A Denicola Archives of biochemistry and biophysics 590, 101-108, 2016	23	2016
The selenoprotein methionine sulfoxide reductase B1 (MSRB1) L Tarrago, A Kaya, HY Kim, B Manta, BC Lee, VN Gladyshev Free Radical Biology and Medicine 191, 228-240, 2022	19	2022
A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes S Ebersoll, B Musunda, T Schmenger, N Dirdjaja, M Bonilla, B Manta, ... Redox Biology 15, 532-547, 2018	19	2018

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