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Ryan L Kyle
Ryan L Kyle
Sitryx Therapeutics
Dirección de correo verificada de sitryx.com
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Unraveling the complex interplay between T cell metabolism and function
RI Klein Geltink, RL Kyle, EL Pearce
Annual review of immunology 36, 461-488, 2018
6532018
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells
B Roediger, R Kyle, KH Yip, N Sumaria, TV Guy, BS Kim, AJ Mitchell, ...
Nature immunology 14 (6), 564-573, 2013
5032013
Mitochondrial priming by CD28
RIK Geltink, D O’Sullivan, M Corrado, A Bremser, MD Buck, JM Buescher, ...
Cell 171 (2), 385-397. e11, 2017
2762017
Polyamines and eIF5A hypusination modulate mitochondrial respiration and macrophage activation
DJ Puleston, MD Buck, RIK Geltink, RL Kyle, G Caputa, D O’Sullivan, ...
Cell metabolism 30 (2), 352-363. e8, 2019
2592019
Mitochondrial integrity regulated by lipid metabolism is a cell-intrinsic checkpoint for Treg suppressive function
CS Field, F Baixauli, RL Kyle, DJ Puleston, AM Cameron, DE Sanin, ...
Cell metabolism 31 (2), 422-437. e5, 2020
2582020
Acetate promotes T cell effector function during glucose restriction
J Qiu, M Villa, DE Sanin, MD Buck, D O’Sullivan, R Ching, M Matsushita, ...
Cell reports 27 (7), 2063-2074. e5, 2019
2422019
Inflammatory macrophage dependence on NAD+ salvage is a consequence of reactive oxygen species–mediated DNA damage
AM Cameron, A Castoldi, DE Sanin, LJ Flachsmann, CS Field, ...
Nature immunology 20 (4), 420-432, 2019
2072019
ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms
T Bouchery, R Kyle, M Camberis, A Shepherd, K Filbey, A Smith, M Harvie, ...
Nature communications 6 (1), 6970, 2015
1752015
IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation
B Roediger, R Kyle, SS Tay, AJ Mitchell, HA Bolton, TV Guy, SY Tan, ...
Journal of Allergy and Clinical Immunology 136 (6), 1653-1663. e7, 2015
1472015
The differentiation of CD4+ T-helper cell subsets in the context of helminth parasite infection
T Bouchery, R Kyle, F Ronchese, G Le Gros
Frontiers in immunology 5, 112572, 2014
832014
Type II-activated murine macrophages produce IL-4
AC La Flamme, M Kharkrang, S Stone, S Mirmoeini, D Chuluundorj, ...
Public Library of Science 7 (10), e46989, 2012
662012
Thymic stromal lymphopoietin drives the development of IL-13+ Th2 cells
S Ochiai, F Jagot, RL Kyle, E Hyde, RF White, M Prout, AJ Schmidt, ...
Proceedings of the National Academy of Sciences 115 (5), 1033-1038, 2018
652018
Dynamic cardiolipin synthesis is required for CD8+ T cell immunity
M Corrado, J Edwards-Hicks, M Villa, LJ Flachsmann, DE Sanin, ...
Cell metabolism 32 (6), 981-995. e7, 2020
422020
Dermal group 2 innate lymphoid cells in atopic dermatitis and allergy
B Roediger, R Kyle, G Le Gros, W Weninger
Current opinion in immunology 31, 108-114, 2014
372014
Fever supports CD8+ effector T cell responses by promoting mitochondrial translation
D O’Sullivan, MA Stanczak, M Villa, FM Uhl, M Corrado, RI Klein Geltink, ...
Proceedings of the National Academy of Sciences 118 (25), e2023752118, 2021
352021
IL-4 is a key requirement for IL-4-and IL-4/IL-13-expressing CD4 Th2 subsets in lung and skin
MS Prout, RL Kyle, F Ronchese, G Le Gros
Frontiers in immunology 9, 354798, 2018
342018
IL-4 haploinsufficiency specifically impairs IgE responses against allergens in mice
MJ Robinson, M Prout, H Mearns, R Kyle, M Camberis, EE Forbes-Blom, ...
The Journal of Immunology 198 (5), 1815-1822, 2017
322017
Evaluating the in vivo Th2 priming potential among common allergens
M Camberis, M Prout, SC Tang, E Forbes-Blom, M Robinson, R Kyle, ...
Journal of immunological methods 394 (1-2), 62-72, 2013
242013
IL‐25 exhibits disparate roles during Th2‐cell differentiation versus effector function
H Mearns, EE Forbes‐Blom, M Camberis, SC Tang, R Kyle, M Harvie, ...
European Journal of Immunology 44 (7), 1976-1980, 2014
222014
Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection
AM Kabat, A Hackl, DE Sanin, P Zeis, KM Grzes, F Baixauli, R Kyle, ...
Science Immunology 7 (76), eadd3263, 2022
132022
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